7ZYX

Dimeric i-motif from 2'Farabinocytidine-modified TC5

Summary for 7ZYX

• Entry DOI: 10.2210/pdb7zyx/pdb
• NMR Information: BMRB: 34735
• Descriptor: DNA (5'-D(*TP*(CFL)P*(CFL)P*(CFL)P*(CFL)P*(CFL))-3') (1 entity in total)
• Functional Keywords: i-motif, fana, 2'farabinocytidine, dna
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 3590.20

Authors

Garavis, M.,El Khoury, R.,Damha, M.J.,Gonzalez, C. (deposition date: 2022-05-25, release date: 2023-03-01)

• Primary citation: El-Khoury, R.,Macaluso, V.,Hennecker, C.,Mittermaier, A.K.,Orozco, M.,Gonzalez, C.,Garavis, M.,Damha, M.J.; i-Motif folding intermediates with zero-nucleotide loops are trapped by 2'-fluoroarabinocytidine via F···H and O···H hydrogen bonds.; Commun Chem, 6:31-31, 2023; PubMed: 36797370; DOI: 10.1038/s42004-023-00831-7

Experimental method

SOLUTION NMR