8UWP
 
 | | Crystal structure of SETDB1 Tudor domain in complex with MR46747 | | 分子名称: | (3S)-N-(4-chloro-3-{[2-(diethylamino)ethyl]carbamoyl}phenyl)-3-(diethylamino)pyrrolidine-1-carboxamide, 1,2-ETHANEDIOL, Histone-lysine N-methyltransferase SETDB1, ... | | 著者 | Shrestha, S, Beldar, S, Dong, A, Ackloo, S, Brown, P.J, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | | 登録日 | 2023-11-07 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal structure of SETDB1 Tudor domain in complex with MR46747
To be published
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8VL7
 | | Co-crystal structure of human TREX1 in complex with an inhibitor | | 分子名称: | (2P)-2-[3-bromo-2-(2-hydroxyethoxy)phenyl]-5-hydroxy-1-methyl-N-(1,2-oxazol-4-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Dehghani-Tafti, S, Dong, A, Li, Y, Ackloo, S, Arrowsmith, C.H, Edwards, A.M, Halabelian, L. | | 登録日 | 2024-01-11 | | 公開日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Co-crystal structure of human TREX1 in complex with an inhibitor
To be published
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6OGN
 | | Crystal structure of mouse protein arginine methyltransferase 7 in complex with SGC8158 chemical probe | | 分子名称: | 5'-S-(4-{[(4'-chloro[1,1'-biphenyl]-3-yl)methyl]amino}butyl)-5'-thioadenosine, Protein arginine N-methyltransferase 7, UNKNOWN ATOM OR ION, ... | | 著者 | Halabelian, L, Dong, A, Zeng, H, Li, Y, Hutchinson, A, Seitova, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | 登録日 | 2019-04-03 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response.
Nat Commun, 11, 2020
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2H01
 | | PY00414- Plasmodium yoelii thioredoxin peroxidase I | | 分子名称: | 2-CYS PEROXIREDOXIN | | 著者 | Artz, J, Qiu, W, Min, J.R, Dong, A, Lew, J, Melone, M, Alam, Z, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC) | | 登録日 | 2006-05-12 | | 公開日 | 2006-05-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of PY00414 - a Plasmodium yoelii thioredoxin peroxidase I
To be Published
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3S8I
 | | The retroviral-like protease (RVP) domain of human DDI1 | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... | | 著者 | Walker, J.R, Asinas, A, Dong, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2011-05-28 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Retropepsin-Like Domain of Human DDI1
To be Published
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2I81
 | | Crystal Structure of Plasmodium vivax 2-Cys Peroxiredoxin, Reduced | | 分子名称: | 2-Cys Peroxiredoxin | | 著者 | Artz, J.D, Qiu, W, Dong, A, Lew, J, Ren, H, Zhao, Y, Kozieradski, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC) | | 登録日 | 2006-08-31 | | 公開日 | 2006-09-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal Structure of Plasmodium vivax 2-Cys Peroxiredoxin, Reduced
To be published
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5UBB
 | | Crystal structure of human alpha N-terminal protein methyltransferase 1B | | 分子名称: | Alpha N-terminal protein methyltransferase 1B, S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION | | 著者 | Dong, C, Zhu, L, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2016-12-20 | | 公開日 | 2017-03-22 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2.
Commun Biol, 1, 2018
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3TYR
 | | Crystal structure of transcriptional regulator VanUg, Form I | | 分子名称: | Transcriptional regulator | | 著者 | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Dong, A, Depardieu, F, Courvalin, P, Shabalin, I, Chruszcz, M, Minor, W, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2011-09-26 | | 公開日 | 2011-10-12 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | | 主引用文献 | Crystal structure of transcriptional regulator VanUg, Form I
TO BE PUBLISHED
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3OI7
 | | Structure of the structure of the H13A mutant of Ykr043C in complex with sedoheptulose-1,7-bisphosphate | | 分子名称: | 1,2-ETHANEDIOL, 1,7-di-O-phosphono-beta-D-altro-hept-2-ulofuranose, GLYCEROL, ... | | 著者 | Singer, A.U, Xu, X, Dong, A, Cui, H, Clasquin, M.F, Caudy, A.A, Edwards, A.M, Savchenko, A, Joachimiak, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-08-18 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Riboneogenesis in yeast.
Cell(Cambridge,Mass.), 145, 2011
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2AYV
 | | Crystal structure of a putative ubiquitin-conjugating enzyme E2 from Toxoplasma gondii | | 分子名称: | UNKNOWN ATOM OR ION, ubiquitin-conjugating enzyme E2 | | 著者 | Tempel, W, Dong, A, Zhao, Y, Lew, J, Alam, Z, Melone, M, Wasney, G, Kozieradzki, I, Vedadi, M, Arrowsmith, C, Sundstrom, M, Weigelt, J, Edwards, A, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC) | | 登録日 | 2005-09-08 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
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3D1R
 | | Structure of E. coli GlpX with its substrate fructose 1,6-bisphosphate | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Singer, A, Skarina, T, Dong, A, Brown, G, Joachimiak, A, Edwards, A.M, Yakunin, A.F, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-05-06 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and Biochemical Characterization of the Type II Fructose-1,6-bisphosphatase GlpX from Escherichia coli.
J.Biol.Chem., 284, 2009
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3N72
 | | Crystal Structure of Aha-1 from plasmodium falciparum, PFC0270w | | 分子名称: | THIOCYANATE ION, putative activator of HSP90 | | 著者 | Wernimont, A.K, Dong, A, Hutchinson, A, Sullivan, H, Mackenzie, F, Kozieradzki, I, Cossar, D, Bochkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC) | | 登録日 | 2010-05-26 | | 公開日 | 2010-07-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal Structure of Aha-1 from plasmodium falciparum, PFC0270w
To be Published
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3NIZ
 | | Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with ADP bound. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rhodanese family protein | | 著者 | Wernimont, A.K, Dong, A, Lew, J, Lin, Y.H, Hassanali, A, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bochkarev, A, Hui, R, Artz, J.D, Structural Genomics Consortium (SGC) | | 登録日 | 2010-06-16 | | 公開日 | 2010-07-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with ADP bound.
To be Published
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4PYZ
 | | Crystal structure of the first two Ubl domains of Deubiquitylase USP7 | | 分子名称: | UNKNOWN ATOM OR ION, Ubiquitin carboxyl-terminal hydrolase 7 | | 著者 | Walker, J.R, Dong, A, Ong, M.S, Dhe-Paganon, S, Kania, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2014-03-28 | | 公開日 | 2014-04-16 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Crystal structure of the first two Ubl domains of Deubiquitylase USP7
to be published
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1YXO
 | | Crystal Structure of pyridoxal phosphate biosynthetic protein PdxA PA0593 | | 分子名称: | 4-hydroxythreonine-4-phosphate dehydrogenase 1, ETHANOL, MAGNESIUM ION | | 著者 | Liu, Y, Xu, X, Dong, A, Kudritskam, M, Savchenko, A, Pai, E.F, Joachimiak, A, Edwards, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-02-22 | | 公開日 | 2005-04-05 | | 最終更新日 | 2011-10-05 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Crystal Structure of pyridoxal phosphate biosynthetic protein PdxA PA0593
To be Published
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4NXJ
 | | Crystal Structure of PF3D7_1475600, a bromodomain from Plasmodium Falciparum | | 分子名称: | Bromodomain protein | | 著者 | Wernimont, A.K, Loppnau, P, Knapp, S, Fonseca, M, Brennan, P.E, Dong, A, Walker, J.R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Hutchinson, A, Structural Genomics Consortium (SGC) | | 登録日 | 2013-12-09 | | 公開日 | 2014-03-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Crystal Structure of PF3D7_1475600, a bromodomain from Plasmodium Falciparum
TO BE PUBLISHED
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3PKJ
 | | Human SIRT6 crystal structure in complex with 2'-N-Acetyl ADP ribose | | 分子名称: | NAD-dependent deacetylase sirtuin-6, SULFATE ION, UNKNOWN ATOM OR ION, ... | | 著者 | Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Walker, J.R, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC) | | 登録日 | 2010-11-11 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structure and biochemical functions of SIRT6.
J.Biol.Chem., 286, 2011
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3PFY
 | | The catalytic domain of human OTUD5 | | 分子名称: | DI(HYDROXYETHYL)ETHER, OTU domain-containing protein 5, SULFATE ION, ... | | 著者 | Walker, J.R, Asinas, A.E, Crombet, L, Dong, A, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2010-10-29 | | 公開日 | 2010-12-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | | 主引用文献 | The catalytic domain of human OTUD5
To be Published
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3PPA
 | | Structure of the Dusp-Ubl domains of Usp15 | | 分子名称: | CITRIC ACID, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 15 | | 著者 | Walker, J.R, Asinas, A.E, Dong, A, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2010-11-24 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure of the Dusp-Ubl Domains of the Ubiquitin-Specific Protease 15
To be Published
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2B0R
 | | Crystal Structure of Cyclase-Associated Protein from Cryptosporidium parvum | | 分子名称: | UNKNOWN ATOM OR ION, possible adenyl cyclase-associated protein | | 著者 | Tempel, W, Dong, A, Zhao, Y, Lew, J, Kozieradzki, I, Alam, Z, Melone, M, Wasney, G, Vedadi, M, Arrowsmith, C, Edwards, A, Weigelt, J, Sundstrom, M, Hui, R, Bochkarev, A, Artz, J, Structural Genomics Consortium (SGC) | | 登録日 | 2005-09-14 | | 公開日 | 2005-09-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure and function of a G-actin sequestering protein with a vital role in malaria oocyst development inside the mosquito vector
J.Biol.Chem., 151, 2010
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4TVR
 | | Tandem Tudor and PHD domains of UHRF2 | | 分子名称: | E3 ubiquitin-protein ligase UHRF2, UNKNOWN ATOM OR ION, ZINC ION | | 著者 | Walker, J.R, Dong, A, Zhang, Q, Ong, M, Duan, S, Li, Y, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2014-06-27 | | 公開日 | 2015-06-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Structure of the Tandem Tudor and PHD domains of UHRF2
To be published
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3PKI
 | | Human SIRT6 crystal structure in complex with ADP ribose | | 分子名称: | NAD-dependent deacetylase sirtuin-6, SULFATE ION, UNKNOWN ATOM OR ION, ... | | 著者 | Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Bochkarev, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC) | | 登録日 | 2010-11-11 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structure and biochemical functions of SIRT6.
J.Biol.Chem., 286, 2011
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3OMB
 | | Crystal structure of extracellular solute-binding protein from Bifidobacterium longum subsp. infantis | | 分子名称: | Extracellular solute-binding protein, family 1, MAGNESIUM ION | | 著者 | Chang, C, Xu, X, Chin, S, Cui, H, Dong, A, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-08-26 | | 公開日 | 2010-09-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of extracellular solute-binding protein from Bifidobacterium longum subsp. infantis
To be Published
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2B25
 | | Human putative tRNA(1-methyladenosine)methyltransferase | | 分子名称: | S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION, hypothetical protein | | 著者 | Tempel, W, Wu, H, Dong, A, Zeng, H, Loppnau, P, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | 登録日 | 2005-09-16 | | 公開日 | 2005-09-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Human putative tRNA(1-methyladenosine)methyltransferase
To be Published
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1YQE
 | | Crystal Structure of Conserved Protein of Unknown Function AF0625 | | 分子名称: | Hypothetical UPF0204 protein AF0625, PYROPHOSPHATE 2- | | 著者 | Liu, Y, Skarina, T, Dong, A, Kudritskam, M, Savchenko, A, Pai, E.F, Edwards, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-02-01 | | 公開日 | 2005-03-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Crystal Structure of Conserved Hypothetical Protein AF0625
To be Published
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