8UWP

Crystal structure of SETDB1 Tudor domain in complex with MR46747

Summary for 8UWP

• Entry DOI: 10.2210/pdb8uwp/pdb
• Descriptor: Histone-lysine N-methyltransferase SETDB1, (3S)-N-(4-chloro-3-{[2-(diethylamino)ethyl]carbamoyl}phenyl)-3-(diethylamino)pyrrolidine-1-carboxamide, SULFATE ION, ... (6 entities in total)
• Functional Keywords: setdb1, epigenetics, methyllysine reader, sgc, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 54747.77

Authors

Shrestha, S.,Beldar, S.,Dong, A.,Ackloo, S.,Brown, P.J.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (deposition date: 2023-11-07, release date: 2023-11-22, Last modification date: 2024-01-17)

• Primary citation: Shrestha, S.,Beldar, S.,Dong, A.,Ackloo, S.,Brown, P.J.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC); Crystal structure of SETDB1 Tudor domain in complex with MR46747; To be published,

Experimental method

X-RAY DIFFRACTION (1.77 Å)