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PDB: 1599 results

5BWZ
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BU of 5bwz by Molmil
Crystal structure of S39E HDAC8 in complex with Droxinostat
Descriptor: Droxinostat, GLYCEROL, Histone deacetylase 8, ...
Authors:Decroos, C, Christianson, D.W.
Deposit date:2015-06-08
Release date:2016-06-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Phosphorylation of Histone Deacetylase 8: Structural and Mechanistic Analysis of the Phosphomimetic S39E Mutant.
Biochemistry, 58, 2019
4OFS
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BU of 4ofs by Molmil
Crystal structure of a truncated catalytic core of the 2-oxoacid dehydrogenase multienzyme complex from Thermoplasma acidophilum
Descriptor: Probable lipoamide acyltransferase
Authors:Marrot, N.L, Marshall, J.J.T, Svergun, D.I, Crennell, S.J, Hough, D.W, van den Elsen, J.M.H, Danson, M.J.
Deposit date:2014-01-15
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Why are the 2-oxoacid dehydrogenase complexes so large? Generation of an active trimeric complex.
Biochem.J., 463, 2014
3LW8
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BU of 3lw8 by Molmil
Shigella IpgB2 in complex with human RhoA, GDP and Mg2+ (complex A)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, IpgB2, MAGNESIUM ION, ...
Authors:Klink, B.U, Barden, S, Heidler, T.V, Borchers, C, Ladwein, M, Stradal, T.E.B, Rottner, K, Heinz, D.W.
Deposit date:2010-02-23
Release date:2010-03-31
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry
J.Biol.Chem., 285, 2010
8EAX
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BU of 8eax by Molmil
Octameric prenyltransferase domain of fusicoccadiene Synthase with C2 symmetry sans transiently associating cyclase domains
Descriptor: Fusicoccadiene synthase
Authors:Faylo, J.L, van Eeuwen, T, Christianson, D.W.
Deposit date:2022-08-29
Release date:2022-11-02
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Transient Prenyltransferase-Cyclase Association in Fusicoccadiene Synthase, an Assembly-Line Terpene Synthase.
Biochemistry, 61, 2022
5CIS
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BU of 5cis by Molmil
The CUB1-EGF-CUB2 domains of rat MBL-associated serine protease-2 (MASP-2) bound to Ca2+
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mannan-binding lectin serine peptidase 2
Authors:Nan, R, Furze, C.M, Wright, D.W, Gor, J, Wallis, R, Perkins, S.J.
Deposit date:2015-07-13
Release date:2017-01-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25, 2017
5CKM
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BU of 5ckm by Molmil
The CUB1-EGF-CUB2 domains of rat MBL-associated serine protease-2 (MASP-2) bound to Ca2+
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mannan-binding lectin serine peptidase 2
Authors:Nan, R, Furze, C.M, Wright, D.W, Gor, J, Wallis, R, Perkins, S.J.
Deposit date:2015-07-15
Release date:2017-01-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25, 2017
8SU4
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BU of 8su4 by Molmil
F198S epi-Isozizaene Synthase: complex with 3 Mg2+, inorganic pyrophosphate, and benzyl triethyl ammonium cation
Descriptor: Epi-isozizaene synthase, GLYCEROL, MAGNESIUM ION, ...
Authors:Eaton, S.A, Christianson, D.W.
Deposit date:2023-05-11
Release date:2023-07-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Reprogramming the Cyclization Cascade of epi -Isozizaene Synthase to Generate Alternative Terpene Products.
Biochemistry, 62, 2023
8SU0
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BU of 8su0 by Molmil
Unliganded F96H epi-Isozizaene Synthase
Descriptor: Epi-isozizaene synthase, SULFATE ION
Authors:Eaton, S.A, Christianson, D.W.
Deposit date:2023-05-11
Release date:2023-07-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Reprogramming the Cyclization Cascade of epi -Isozizaene Synthase to Generate Alternative Terpene Products.
Biochemistry, 62, 2023
8SW1
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BU of 8sw1 by Molmil
Puromycin-sensitive aminopeptidase with bound peptide
Descriptor: Polyglutamine peptide, Puromycin-sensitive aminopeptidase, ZINC ION
Authors:Rodgers, D.W, Madabushi, S.
Deposit date:2023-05-17
Release date:2023-07-26
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structure of puromycin-sensitive aminopeptidase and polyglutamine binding.
Plos One, 18, 2023
8SU1
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BU of 8su1 by Molmil
F96H epi-Isozizaene Synthase: complex with 3 Mg2+ and pamidronate
Descriptor: Epi-isozizaene synthase, MAGNESIUM ION, PAMIDRONATE, ...
Authors:Eaton, S.A, Christianson, D.W.
Deposit date:2023-05-11
Release date:2023-07-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Reprogramming the Cyclization Cascade of epi -Isozizaene Synthase to Generate Alternative Terpene Products.
Biochemistry, 62, 2023
8SU3
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BU of 8su3 by Molmil
F95S epi-Isozizaene Synthase: complex with 3 Mg2+, inorganic pyrophosphate, and benzyl triethyl ammonium cation
Descriptor: Epi-isozizaene synthase, GLYCEROL, MAGNESIUM ION, ...
Authors:Eaton, S.A, Christianson, D.W.
Deposit date:2023-05-11
Release date:2023-07-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Reprogramming the Cyclization Cascade of epi -Isozizaene Synthase to Generate Alternative Terpene Products.
Biochemistry, 62, 2023
3LGK
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BU of 3lgk by Molmil
D99N Epi-isozizaene synthase
Descriptor: Epi-isozizaene synthase, SULFATE ION
Authors:Aaron, J.A, Lin, X, Cane, D.E, Christianson, D.W.
Deposit date:2010-01-20
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.892 Å)
Cite:Structure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates
Biochemistry, 49, 2010
8SU5
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BU of 8su5 by Molmil
F198T epi-Isozizaene Synthase: complex with 3 Mg2+, inorganic pyrophosphate, and benzyl triethyl ammonium cation
Descriptor: Epi-isozizaene synthase, GLYCEROL, MAGNESIUM ION, ...
Authors:Eaton, S.A, Christianson, D.W.
Deposit date:2023-05-11
Release date:2023-07-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Reprogramming the Cyclization Cascade of epi -Isozizaene Synthase to Generate Alternative Terpene Products.
Biochemistry, 62, 2023
8SU2
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BU of 8su2 by Molmil
F96H epi-Isozizaene Synthase: complex with 3 Mg2+ and risedronate
Descriptor: 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, Epi-isozizaene synthase, GLYCEROL, ...
Authors:Eaton, S.A, Christianson, D.W.
Deposit date:2023-05-11
Release date:2023-07-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Reprogramming the Cyclization Cascade of epi -Isozizaene Synthase to Generate Alternative Terpene Products.
Biochemistry, 62, 2023
8SW0
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BU of 8sw0 by Molmil
Puromycin sensitive aminopeptidase
Descriptor: 1,4-DIETHYLENE DIOXIDE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Puromycin-sensitive aminopeptidase, ...
Authors:Rodgers, D.W, Sampath, S.
Deposit date:2023-05-17
Release date:2023-07-26
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structure of puromycin-sensitive aminopeptidase and polyglutamine binding.
Plos One, 18, 2023
3LP7
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BU of 3lp7 by Molmil
Crystal structure of Human Arginase I in complex with inhibitor N(omega)-hydroxy-L-arginine (NOHA), 2.04A Resolution
Descriptor: Arginase-1, MANGANESE (II) ION, N-OMEGA-HYDROXY-L-ARGININE
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2010-02-04
Release date:2010-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Inhibition of human arginase I by substrate and product analogues.
Arch.Biochem.Biophys., 496, 2010
8E4R
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BU of 8e4r by Molmil
Room-temperature X-ray structure of SARS-CoV-2 main protease H41A miniprecursor mutant in complex with GC373
Descriptor: (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, Replicase polyprotein 1ab
Authors:Coates, L, Kneller, D.W, Kovalevsky, A.
Deposit date:2022-08-18
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Unmasking the Conformational Stability and Inhibitor Binding to SARS-CoV-2 Main Protease Active Site Mutants and Miniprecursor.
J.Mol.Biol., 434, 2022
8E4J
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BU of 8e4j by Molmil
Room-temperature X-ray structure of SARS-CoV-2 main protease H41A miniprecursor mutant
Descriptor: Replicase polyprotein 1ab
Authors:Coates, L, Kneller, D.W, Kovalevsky, A.
Deposit date:2022-08-18
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Unmasking the Conformational Stability and Inhibitor Binding to SARS-CoV-2 Main Protease Active Site Mutants and Miniprecursor.
J.Mol.Biol., 434, 2022
5CKN
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BU of 5ckn by Molmil
The CUB1-EGF-CUB2 domains of rat MBL-associated serine protease-2 (MASP-2) bound to Ca2+
Descriptor: CALCIUM ION, Mannan-binding lectin serine peptidase 2
Authors:Nan, R, Furze, C.M, Wright, D.W, Gor, J, Wallis, R, Perkins, S.J.
Deposit date:2015-07-15
Release date:2017-01-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25, 2017
8SWA
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BU of 8swa by Molmil
Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with SAM and PPNP
Descriptor: (DIPHOSPHONO)AMINOPHOSPHONIC ACID, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Bruemmer, K.J, Pham, V.N, Toh, J.D.W.
Deposit date:2023-05-18
Release date:2023-11-15
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Formaldehyde regulates S -adenosylmethionine biosynthesis and one-carbon metabolism.
Science, 382, 2023
4PHB
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BU of 4phb by Molmil
Structure of the polysaccharide lyase-like protein Cthe_2159 from C. thermocellum, Gadolinium derivative
Descriptor: GADOLINIUM ATOM, Uncharacterized protein
Authors:Close, D.W, D'Angelo, S, Bradbury, A.R.M.
Deposit date:2014-05-06
Release date:2014-08-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1781 Å)
Cite:A new family of beta-helix proteins with similarities to the polysaccharide lyases.
Acta Crystallogr.,Sect.D, 70, 2014
3LBX
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BU of 3lbx by Molmil
Crystal Structure of the Erythrocyte Spectrin Tetramerization Domain Complex
Descriptor: Spectrin alpha chain, erythrocyte, Spectrin beta chain
Authors:Ipsaro, J.J, Harper, S.L, Messick, T.E, Marmorstein, R, Mondragon, A, Speicher, D.W.
Deposit date:2010-01-08
Release date:2010-03-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex.
Blood, 115, 2010
3LP4
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BU of 3lp4 by Molmil
Crystal structure of human arginase I in complex with L-LYSINE, 1.90A Resolution.
Descriptor: Arginase-1, LYSINE, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2010-02-04
Release date:2010-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Inhibition of human arginase I by substrate and product analogues.
Arch.Biochem.Biophys., 496, 2010
4PCS
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BU of 4pcs by Molmil
Crystal structure of a bacterial fucosidase with iminosugar (2S,3S,4R,5S)-3,4-dihydroxy-2-[2'-phenyl]ethynyl-5-methylpyrrolidine
Descriptor: (2S,3R,4S,5S)-2-methyl-5-(phenylethynyl)pyrrolidine-3,4-diol, Alpha-L-fucosidase, IMIDAZOLE, ...
Authors:Davies, G.J, Wright, D.W, Behr, J.B.
Deposit date:2014-04-16
Release date:2014-07-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Exploiting the Hydrophobic Terrain in Fucosidases with Aryl-Substituted Pyrrolidine Iminosugars.
Chembiochem, 16, 2015
3LG5
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BU of 3lg5 by Molmil
F198A Epi-isozizaene synthase: Complex with Mg, inorganic pyrophosphate and benzyl triethyl ammonium cation
Descriptor: Epi-isozizaene synthase, MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, ...
Authors:Aaron, J.A, Lin, X, Cane, D.E, Christianson, D.W.
Deposit date:2010-01-19
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.641 Å)
Cite:Structure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates
Biochemistry, 49, 2010

224201

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