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PDB: 1599 件
5ER8
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BU of 5er8 by Molmil
Crystal structure of cyclization domain of Phomopsis amygdali fusicoccadiene synthase complexed with manganese ions and neridronate
分子名称: (6-azanyl-1-oxidanyl-1-phosphono-hexyl)phosphonic acid, CHLORIDE ION, Fusicoccadiene synthase, ...
著者Chen, M, Christianson, D.W.
登録日2015-11-13
公開日2016-01-20
最終更新日2016-04-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase.
Acs Chem.Biol., 11, 2016
4Q42
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BU of 4q42 by Molmil
Crystal structure of Schistosoma mansoni arginase in complex with L-ornithine
分子名称: Arginase, GLYCEROL, L-ornithine, ...
著者Hai, Y, Edwards, J.E, Van Zandt, M.C, Hoffmann, K.F, Christianson, D.W.
登録日2014-04-12
公開日2014-07-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.051 Å)
主引用文献Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
Biochemistry, 53, 2014
4QA4
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BU of 4qa4 by Molmil
Crystal structure of H334R HDAC8 in complex with M344
分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, GLYCEROL, Histone deacetylase 8, ...
著者Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W.
登録日2014-05-02
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders.
Acs Chem.Biol., 9, 2014
4QNJ
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BU of 4qnj by Molmil
The structure of wt A. thaliana IGPD2 in complex with Mn2+ and formate at 1.3A resolution
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, FORMIC ACID, ...
著者Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R, Hawkes, T.R, Baker, P.J, Rice, D.W.
登録日2014-06-18
公開日2015-06-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
Structure, 23, 2015
3MFW
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BU of 3mfw by Molmil
Crystal structure of human arginase I in complex with L-2-aminohistidine and sulphate
分子名称: 2-amino-L-histidine, Arginase-1, MANGANESE (II) ION, ...
著者Di Costanzo, L, Christianson, D.W.
登録日2010-04-04
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I.
J.Med.Chem., 53, 2010
3MMR
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BU of 3mmr by Molmil
Structure of Plasmodium falciparum Arginase in complex with ABH
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase, BETA-MERCAPTOETHANOL, ...
著者Dowling, D.P, Ilies, M, Olszewski, K.L, Portugal, S, Mota, M.M, Llinas, M, Christianson, D.W.
登録日2010-04-20
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystal structure of arginase from Plasmodium falciparum and implications for L-arginine depletion in malarial infection .
Biochemistry, 49, 2010
4QA0
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BU of 4qa0 by Molmil
Crystal structure of C153F HDAC8 in complex with SAHA
分子名称: GLYCEROL, Histone deacetylase 8, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ...
著者Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W.
登録日2014-05-02
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.242 Å)
主引用文献Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders.
Acs Chem.Biol., 9, 2014
4QA3
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BU of 4qa3 by Molmil
Crystal structure of T311M HDAC8 in complex with Trichostatin A (TSA)
分子名称: GLYCEROL, Histone deacetylase 8, POTASSIUM ION, ...
著者Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W.
登録日2014-05-02
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.876 Å)
主引用文献Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders.
Acs Chem.Biol., 9, 2014
3NH9
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BU of 3nh9 by Molmil
Nucleotide Binding Domain of Human ABCB6 (ATP bound structure)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family B member 6, mitochondrial, ...
著者Haffke, M, Menzel, A, Carius, Y, Jahn, D, Heinz, D.W.
登録日2010-06-14
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides.
Acta Crystallogr.,Sect.D, 66, 2010
4QA7
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BU of 4qa7 by Molmil
Crystal structure of H334R/Y306F HDAC8 in complex with a tetrapeptide substrate
分子名称: 7-AMINO-4-METHYL-CHROMEN-2-ONE, GLYCEROL, Histone deacetylase 8, ...
著者Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W.
登録日2014-05-02
公開日2014-08-06
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders.
Acs Chem.Biol., 9, 2014
3L25
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BU of 3l25 by Molmil
Crystal structure of Zaire Ebola VP35 interferon inhibitory domain bound to 8 bp dsRNA
分子名称: CHLORIDE ION, FORMIC ACID, GLYCEROL, ...
著者Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K.
登録日2009-12-14
公開日2010-01-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Nat.Struct.Mol.Biol., 17, 2010
3KV2
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BU of 3kv2 by Molmil
HIGH RESOLUTION STRUCTURE OF HUMAN ARGINASE I IN COMPLEX WITH THE STRONG INHIBITOR N(omega)-hydroxy-nor-L-arginine (nor-NOHA)
分子名称: Arginase-1, MANGANESE (II) ION, NOR-N-OMEGA-HYDROXY-L-ARGININE
著者Di Costanzo, L, Christianson, D.W.
登録日2009-11-28
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Inhibition of human arginase I by substrate and product analogues.
Arch.Biochem.Biophys., 496, 2010
4PS0
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BU of 4ps0 by Molmil
Caspase-8 specific unnatural amino acid peptides
分子名称: (BAL)LQ(HYP)(1U8) PEPTIDE, Caspase-3
著者Wolan, D.W, Vickers, C.J, Gonzalez-Paez, G.E.
登録日2014-03-06
公開日2015-01-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids.
Acs Chem.Biol., 9, 2014
3MJL
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BU of 3mjl by Molmil
Crystal structure of human arginase I in complex with 2-aminoimidazole. Resolution 1.90 A.
分子名称: 1H-imidazol-2-amine, Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2010-04-13
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human arginase I in complex with 2-aminoimidazole. Resolution 1.90 A.
To be Published
3NJ8
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BU of 3nj8 by Molmil
Crystal structure of T. gondii enoyl acyl carrier protein reductase with bound triclosan like inhibitor
分子名称: 3-chloro-4-(2-hydroxy-4-propylphenoxy)benzonitrile, Enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Muench, S.P, Ruzheinikov, S.N, Rice, D.W.
登録日2010-06-17
公開日2010-09-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Identification and development of novel inhibitors of Toxoplasma gondii enoyl reductase.
J.Med.Chem., 53, 2010
3NH6
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BU of 3nh6 by Molmil
Nucleotide Binding Domain of human ABCB6 (apo structure)
分子名称: ATP-binding cassette sub-family B member 6, mitochondrial, BETA-MERCAPTOETHANOL
著者Haffke, M, Menzel, A, Carius, Y, Jahn, D, Heinz, D.W.
登録日2010-06-14
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides.
Acta Crystallogr.,Sect.D, 66, 2010
4QNK
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BU of 4qnk by Molmil
The structure of wt A. thaliana IGPD2 in complex with Mn2+ and phosphate
分子名称: 1,2-ETHANEDIOL, Imidazoleglycerol-phosphate dehydratase 2, chloroplastic, ...
著者Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R, Hawkes, T.R, Baker, P.J, Rice, D.W.
登録日2014-06-18
公開日2015-06-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
Structure, 23, 2015
3NWT
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BU of 3nwt by Molmil
Crystal structure of the N-terminal domain of the yeast telomere-binding and telomerase regulatory protein Cdc13
分子名称: Cell division control protein 13
著者Mitchell, M.T, Smith, J.S, Mason, M, Harper, S, Speicher, D.W, Johnson, F.B, Skordalakes, E.
登録日2010-07-10
公開日2010-09-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cdc13 N-terminal dimerization, DNA binding, and telomere length regulation.
Mol.Cell.Biol., 30, 2010
3NQW
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BU of 3nqw by Molmil
A metazoan ortholog of SpoT hydrolyzes ppGpp and plays a role in starvation responses
分子名称: CG11900, MANGANESE (II) ION, SULFATE ION
著者Sun, D.W, Kim, H.Y, Kim, K.J, Jeon, Y.H, Chung, J.
登録日2010-06-30
公開日2010-09-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses
Nat.Struct.Mol.Biol., 17, 2010
4R1Q
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BU of 4r1q by Molmil
Crystal Structure of Thermophilic Geobacillus kaustophilus L-Arabinose isomerase in complex with L-arabitol
分子名称: L-arabinitol, L-arabinose isomerase, MANGANESE (II) ION
著者Choi, J.M, Lee, Y.J, Lee, D.W, Lee, S.H.
登録日2014-08-07
公開日2015-08-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.248 Å)
主引用文献Crystal Structure of Thermophilic L-Arabinose Isomerase with L-Arabitol from Geobacillus kaustophilus
to be published
4R0V
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BU of 4r0v by Molmil
[FeFe]-hydrogenase Oxygen Inactivation is Initiated by the Modification and Degradation of the H cluster 2Fe Subcluster
分子名称: ARSENIC, CHLORIDE ION, Fe-hydrogenase, ...
著者Swanson, S.D, Ratzloff, M.W, Mulder, D.W, Artz, J.H, Ghose, S, Hoffman, A, White, S, Zadvornyy, O.A, Broderick, J.B, Bothner, B, King, P.W, Peters, J.W.
登録日2014-08-01
公開日2015-01-28
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献[FeFe]-Hydrogenase Oxygen Inactivation Is Initiated at the H Cluster 2Fe Subcluster.
J.Am.Chem.Soc., 137, 2015
4R0E
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BU of 4r0e by Molmil
Crystal Structure of the Poliovirus RNA-Dependent RNA Polymerase Low-Fidelity Mutant 3Dpol H273R
分子名称: RNA-directed RNA polymerase
著者Marcotte, L.L, Gohara, D.W, Filman, D.J, Hogle, J.M.
登録日2014-07-30
公開日2014-11-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Dynamics as a Contributor to Error-prone Replication by an RNA-dependent RNA Polymerase.
J.Biol.Chem., 289, 2014
4R1O
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BU of 4r1o by Molmil
Crystal Structure of Thermophilic Geobacillus kaustophilus L-Arabinose isomerase
分子名称: L-arabinose isomerase
著者Choi, J.M, Lee, Y.J, Lee, D.W, Lee, S.H.
登録日2014-08-07
公開日2015-08-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Crystal Structure of Thermophilic apo L-Arabinose Isomerase from Geobacillus kaustophilus
to be published
1URW
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BU of 1urw by Molmil
CDK2 IN COMPLEX WITH AN IMIDAZO[1,2-b]PYRIDAZINE
分子名称: 2-[4-(N-(3-DIMETHYLAMINOPROPYL)SULPHAMOYL)ANILINO]-, CELL DIVISION PROTEIN KINASE 2
著者Byth, K.F, Cooper, N, Culshaw, J.D, Heaton, D.W, Oakes, S.E, Minshull, C.A, Norman, R.A, Pauptit, R.A, Tucker, J.A, Breed, J, Pannifer, A, Rowsell, S, Stanway, J.J, Valentine, A.L, Thomas, A.P.
登録日2003-11-11
公開日2004-04-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Imidazo[1,2-B]Pyridazines: A Potent and Selective Class of Cyclin-Dependent Kinase Inhibitors
Bioorg.Med.Chem.Lett., 14, 2004
1WVA
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BU of 1wva by Molmil
Crystal structure of human arginase I from twinned crystal
分子名称: Arginase 1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE
著者Di Costanzo, L, Sabio, G, Mora, A, Rodriguez, P.C, Ochoa, A.C, Centeno, F, Christianson, D.W.
登録日2004-12-14
公開日2005-09-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in the immune response
Proc.Natl.Acad.Sci.Usa, 102, 2005

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件を2024-08-28に公開中

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