2PMD
 
 | | The structures of aIF2gamma subunit from the archaeon Sulfolobus solfataricus in the GDP-bound form. | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, PYROPHOSPHATE, ... | | 著者 | Nikonov, O.S, Stolboushkina, E.A, Nikulin, A.D, Hasenohrl, D, Blaesi, U, Manstein, D.J, Fedorov, R.V, Garber, M.B, Nikonov, S.V. | | 登録日 | 2007-04-21 | | 公開日 | 2007-11-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | New Insights into the Interactions of the Translation Initiation Factor 2 from Archaea with Guanine Nucleotides and Initiator tRNA.
J.Mol.Biol., 373, 2007
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7SCI
 | | AM0627 metallopeptidase from Akkermansia muciniphila | | 分子名称: | CHLORIDE ION, FORMIC ACID, Peptidase M60 domain-containing protein, ... | | 著者 | Fernandez, D, Bertozzi, C.R, Shon, D.J. | | 登録日 | 2021-09-28 | | 公開日 | 2022-04-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences.
J.Biol.Chem., 298, 2022
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5M7U
 | | Structure of human O-GlcNAc hydrolase with new iminocyclitol type inhibitor | | 分子名称: | 2-[(2~{R},3~{S},4~{R},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)-1-[3-[3-(trifluoromethyl)phenyl]propyl]pyrrolidin-2-yl]-~{N}-methyl-ethanamide, Protein O-GlcNAcase | | 著者 | Roth, C, Chan, S, Offen, W.A, Hemsworth, G.R, Willems, L.I, King, D, Varghese, V, Britton, R, Vocadlo, D.J, Davies, G.J. | | 登録日 | 2016-10-28 | | 公開日 | 2017-03-29 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and functional insight into human O-GlcNAcase.
Nat. Chem. Biol., 13, 2017
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5MBT
 | | CeuE (H227L, Y288F variant) a periplasmic protein from Campylobacter jejuni | | 分子名称: | Enterochelin uptake periplasmic binding protein | | 著者 | Wilde, E.J, Blagova, E.V, Hughes, A, Raines, D.J, Moroz, O.V, Turkenburg, J.P, Duhme-Klair, A.-K, Wilson, K.S. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length.
Sci Rep, 7, 2017
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5MEK
 | | Sulphotransferase-18 from Arabidopsis thaliana in complex with 3'-phosphoadenosine 5'-phosphate (PAP) | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-3'-5'-DIPHOSPHATE, Cytosolic sulfotransferase 18, ... | | 著者 | Hirschmann, F, Krause, F, Baruch, P, Chizhov, I, Mueller, J.W, Manstein, D.J, Papenbrock, J, Fedorov, R. | | 登録日 | 2016-11-15 | | 公開日 | 2017-07-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structural and biochemical studies of sulphotransferase 18 from Arabidopsis thaliana explain its substrate specificity and reaction mechanism.
Sci Rep, 7, 2017
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8QRO
 | | ASCT2 trimer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS) | | 分子名称: | GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION | | 著者 | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | | 登録日 | 2023-10-09 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2.
Nat Commun, 15, 2024
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7WRN
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8QRU
 | | ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the intermediate outward-facing state (iOFS-down) | | 分子名称: | GLUTAMINE, Neutral amino acid transporter B(0) | | 著者 | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | | 登録日 | 2023-10-09 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2.
Nat Commun, 15, 2024
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8QRV
 | | ASCT2 protomer in lipid nanodiscs under low Na+ concentration in the outward-facing state (OFS) | | 分子名称: | Neutral amino acid transporter B(0), SODIUM ION | | 著者 | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | | 登録日 | 2023-10-09 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2.
Nat Commun, 15, 2024
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8QRP
 | | ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.1) | | 分子名称: | GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION | | 著者 | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | | 登録日 | 2023-10-09 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2.
Nat Commun, 15, 2024
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8QRQ
 | | ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.2) | | 分子名称: | GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION | | 著者 | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | | 登録日 | 2023-10-09 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | | 主引用文献 | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2.
Nat Commun, 15, 2024
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8QRR
 | | ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.3) | | 分子名称: | GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION | | 著者 | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | | 登録日 | 2023-10-09 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | | 主引用文献 | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2.
Nat Commun, 15, 2024
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8QRW
 | | ASCT2 protomer in lipid nanodiscs under low Na+ concentration in the intermediate outward-facing state (iOFS-up) | | 分子名称: | Neutral amino acid transporter B(0), SODIUM ION | | 著者 | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | | 登録日 | 2023-10-09 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2.
Nat Commun, 15, 2024
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5MY1
 | | E. coli expressome | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Kohler, R, Mooney, R.A, Mills, D.J, Kostrewa, D, Landick, R, Cramer, P. | | 登録日 | 2017-01-25 | | 公開日 | 2017-04-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | | 主引用文献 | Architecture of a transcribing-translating expressome.
Science, 356, 2017
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8QRS
 | | ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the intermediate outward-facing state (iOFS-up) | | 分子名称: | GLUTAMINE, Neutral amino acid transporter B(0) | | 著者 | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | | 登録日 | 2023-10-09 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | | 主引用文献 | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2.
Nat Commun, 15, 2024
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5N9Y
 | | The full-length structure of ZntB | | 分子名称: | Zinc transport protein ZntB | | 著者 | Cornelius, G, Stetsenko, A, Scheres, S.H.W, Slotboom, D.J, Guskov, A. | | 登録日 | 2017-02-27 | | 公開日 | 2017-11-15 | | 最終更新日 | 2019-10-23 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | The structural basis of proton driven zinc transport by ZntB.
Nat Commun, 8, 2017
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1DWX
 | | MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER N-hydroxyarginine and tetrahydrobiopterin | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, N-OMEGA-HYDROXY-L-ARGININE, NITRIC OXIDE SYNTHASE, ... | | 著者 | Crane, B.R, Arvai, A.S, Getzoff, E.D, Stuehr, D.J, Tainer, J.A. | | 登録日 | 1999-12-14 | | 公開日 | 2000-02-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of the N(Omega)-Hydroxy-L-Arginine Complex of Inducible Nitric Oxide Synthase Oxygenase Dimer with Active Andinactive Pterins
Biochemistry, 39, 2000
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5NO4
 | | RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate with uS3) | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R. | | 登録日 | 2017-04-10 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (5.16 Å) | | 主引用文献 | RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
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5NO2
 | | RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate) | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R. | | 登録日 | 2017-04-10 | | 公開日 | 2017-05-24 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (5.16 Å) | | 主引用文献 | RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
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7UNX
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1DWV
 | | MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER N-hydroxyarginine and 4-amino tetrahydrobiopterin | | 分子名称: | 2,4-DIAMINO-6-[2,3-DIHYDROXY-PROP-3-YL]-5,6,7,8-TETRAHYDROPTERIDINE, N-OMEGA-HYDROXY-L-ARGININE, NITRIC OXIDE SYNTHASE, ... | | 著者 | Crane, B.R, Arvai, A.S, Getzoff, E.D, Stuehr, D.J, Tainer, J.A. | | 登録日 | 1999-12-14 | | 公開日 | 2000-02-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structures of the N(Omega)-Hydroxy-L-Arginine Complex of Inducible Nitric Oxide Synthase Oxygenase Dimer with Active Andinactive Pterins
Biochemistry, 39, 2000
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8SVP
 | | Crystal structure of pregnane X receptor ligand binding domain in complex with SJPYT-278 | | 分子名称: | (1P)-N-(5-tert-butyl-2-{[(3R)-hexan-3-yl]oxy}phenyl)-1-(2,5-dimethoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide, (1P)-N-(5-tert-butyl-2-{[(3S)-hexan-3-yl]oxy}phenyl)-1-(2,5-dimethoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide, Pregnane X receptor ligand binding domain fused to SRC-1 coactivator peptide | | 著者 | Garcia-Maldonado, E, Huber, A.D, Nithianantham, S, Miller, D.J, Chen, T. | | 登録日 | 2023-05-17 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | | 主引用文献 | Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR.
Nat Commun, 15, 2024
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8SVU
 | | Crystal structure of the L428V mutant of pregnane X receptor ligand binding domain in apo form | | 分子名称: | GLYCEROL, Nuclear receptor subfamily 1 group I member 2, Nuclear receptor coactivator 1 fusion protein,Nuclear receptor coactivator 1 | | 著者 | Garcia-Maldonado, E, Huber, A.D, Nithianantham, S, Miller, D.J, Chen, T. | | 登録日 | 2023-05-17 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR.
Nat Commun, 15, 2024
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7W5N
 | | The crystal structure of the reduced form of Gluconobacter oxydans WSH-004 SNDH | | 分子名称: | L-sorbosone dehydrogenase, NAD(P) dependent, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Li, D, Hou, X.D, Rao, Y.J, Yin, D.J, Zhou, J.W, Chen, J. | | 登録日 | 2021-11-30 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.988 Å) | | 主引用文献 | Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase.
Adv Sci, 10, 2023
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8SVR
 | | Crystal structure of pregnane X receptor ligand binding domain in complex with SJPYT-326 | | 分子名称: | (1P)-N-(5-tert-butyl-2-{[(3S)-hexan-3-yl]oxy}phenyl)-5-methyl-1-(2,4,5-trimethoxyphenyl)-1H-1,2,3-triazole-4-carboxamide, DIMETHYL SULFOXIDE, Pregnane X receptor ligand binding domain fused to SRC-1 coactivator peptide | | 著者 | Garcia-Maldonado, E, Huber, A.D, Nithianantham, S, Miller, D.J, Chen, T. | | 登録日 | 2023-05-17 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR.
Nat Commun, 15, 2024
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