5U79
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![BU of 5u79 by Molmil](/molmil-images/mine/5u79) | Crystal structure of a complex formed between MerB and Dimethyltin | Descriptor: | ACETATE ION, Alkylmercury lyase, BROMIDE ION, ... | Authors: | Wahba, H.M, Stevenson, M, Mansour, A, Sygusch, J, Wilcox, D.E, Omichinski, J.G. | Deposit date: | 2016-12-12 | Release date: | 2017-01-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.604 Å) | Cite: | Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon-Metal Bond Cleavage. J. Am. Chem. Soc., 139, 2017
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5TVN
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![BU of 5tvn by Molmil](/molmil-images/mine/5tvn) | Crystal structure of the LSD-bound 5-HT2B receptor | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, CHOLESTEROL, ... | Authors: | Wacker, D, Wang, S, McCorvy, J.D, Betz, R.M, Venkatakrishnan, A.J, Levit, A, Lansu, K, Schools, Z.L, Che, T, Nichols, D.E, Shoichet, B.K, Dror, R.O, Roth, B.L. | Deposit date: | 2016-11-09 | Release date: | 2017-02-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of an LSD-Bound Human Serotonin Receptor. Cell, 168, 2017
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5U83
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![BU of 5u83 by Molmil](/molmil-images/mine/5u83) | Crystal structure of a MerB-trimethytin complex. | Descriptor: | ACETATE ION, Alkylmercury lyase, BROMIDE ION, ... | Authors: | Wahba, H.M, Stevenson, M, Mansour, A, Sygusch, J, Wilcox, D.E, Omichinski, J.G. | Deposit date: | 2016-12-13 | Release date: | 2017-01-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.609 Å) | Cite: | Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon-Metal Bond Cleavage. J. Am. Chem. Soc., 139, 2017
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3HFN
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![BU of 3hfn by Molmil](/molmil-images/mine/3hfn) | |
3RN8
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![BU of 3rn8 by Molmil](/molmil-images/mine/3rn8) | |
5W87
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![BU of 5w87 by Molmil](/molmil-images/mine/5w87) | |
3REF
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![BU of 3ref by Molmil](/molmil-images/mine/3ref) | Crystal structure of EhRho1 bound to GDP and Magnesium | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho-like small GTPase, ... | Authors: | Bosch, D.E, Qiu, C, Siderovski, D.P. | Deposit date: | 2011-04-04 | Release date: | 2011-09-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Unique structural and nucleotide exchange features of the Rho1 GTPase of Entamoeba histolytica. J.Biol.Chem., 286, 2011
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3RNN
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![BU of 3rnn by Molmil](/molmil-images/mine/3rnn) | |
3IOC
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![BU of 3ioc by Molmil](/molmil-images/mine/3ioc) | Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 2.50 Ang resolution in complex with 5'-deoxy-5'-(benzyldisulfanyl)-adenosine | Descriptor: | (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(benzyldisulfanyl)methyl]tetrahydrofuran-3,4-diol, GLYCEROL, Pantothenate synthetase | Authors: | Ciulli, A, Scott, D.E, Abell, C. | Deposit date: | 2009-08-14 | Release date: | 2009-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A Fragment-Based Approach to Probing Adenosine Recognition Sites by Using Dynamic Combinatorial Chemistry Chembiochem, 10, 2009
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3HFO
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3R7L
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![BU of 3r7l by Molmil](/molmil-images/mine/3r7l) | Crystal Structure of PALA-bound Aspartate Transcarbamoylase from Bacillus subtilis | Descriptor: | Aspartate carbamoyltransferase, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, PHOSPHATE ION | Authors: | Harris, K.M, Cockrell, G.M, Puleo, D.E, Kantrowitz, E.R. | Deposit date: | 2011-03-22 | Release date: | 2011-06-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.585 Å) | Cite: | Crystallographic Snapshots of the Complete Catalytic Cycle of the Unregulated Aspartate Transcarbamoylase from Bacillus subtilis. J.Mol.Biol., 411, 2011
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3R7D
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![BU of 3r7d by Molmil](/molmil-images/mine/3r7d) | Crystal Structure of Unliganded Aspartate Transcarbamoylase from Bacillus subtilis | Descriptor: | Aspartate carbamoyltransferase, PHOSPHATE ION | Authors: | Puleo, D.E, Harris, K.M, Cockrell, G.M, Kantrowitz, E.R. | Deposit date: | 2011-03-22 | Release date: | 2011-06-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.196 Å) | Cite: | Crystallographic Snapshots of the Complete Catalytic Cycle of the Unregulated Aspartate Transcarbamoylase from Bacillus subtilis. J.Mol.Biol., 411, 2011
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3PDS
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![BU of 3pds by Molmil](/molmil-images/mine/3pds) | Irreversible Agonist-Beta2 Adrenoceptor Complex | Descriptor: | 8-hydroxy-5-[(1R)-1-hydroxy-2-({2-[3-methoxy-4-(3-sulfanylpropoxy)phenyl]ethyl}amino)ethyl]quinolin-2(1H)-one, CHOLESTEROL, Fusion protein Beta-2 adrenergic receptor/Lysozyme, ... | Authors: | Rosenbaum, D.M, Zhang, C, Lyons, J.A, Holl, R, Aragao, D, Arlow, D.H, Rasmussen, S.G.F, Choi, H.-J, DeVree, B.T, Sunahara, R.K, Chae, P.S, Gellman, S.H, Dror, R.O, Shaw, D.E, Weis, W.I, Caffrey, M, Gmeiner, P, Kobilka, B.K. | Deposit date: | 2010-10-24 | Release date: | 2011-01-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure and function of an irreversible agonist-beta(2) adrenoceptor complex Nature, 469, 2011
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3FBN
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![BU of 3fbn by Molmil](/molmil-images/mine/3fbn) | Structure of the Mediator submodule Med7N/31 | Descriptor: | Mediator of RNA polymerase II transcription subunit 31, Mediator of RNA polymerase II transcription subunit 7 | Authors: | Koschubs, T, Seizl, M, Lariviere, L, Kurth, F, Baumli, S, Martin, D.E, Cramer, P. | Deposit date: | 2008-11-19 | Release date: | 2008-12-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.007 Å) | Cite: | Identification, structure, and functional requirement of the Mediator submodule Med7N/31 Embo J., 28, 2009
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3PO7
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![BU of 3po7 by Molmil](/molmil-images/mine/3po7) | Human monoamine oxidase B in complex with zonisamide | Descriptor: | 1-(1,2-benzoxazol-3-yl)methanesulfonamide, Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Binda, C, Aldeco, M, Mattevi, A, Edmondson, D.E. | Deposit date: | 2010-11-22 | Release date: | 2011-01-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Interactions of monoamine oxidases with the antiepileptic drug zonisamide: specificity of inhibition and structure of the human monoamine oxidase B complex J.Med.Chem., 54, 2011
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3IOD
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![BU of 3iod by Molmil](/molmil-images/mine/3iod) | Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.75 Ang resolution in complex with 5'-deoxy-5'-((3-nitrobenzyl)disulfanyl)-adenosine | Descriptor: | (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-{[(3-nitrobenzyl)disulfanyl]methyl}tetrahydrofuran-3,4-diol, ETHANOL, GLYCEROL, ... | Authors: | Ciulli, A, Scott, D.E, Abell, C. | Deposit date: | 2009-08-14 | Release date: | 2009-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A Fragment-Based Approach to Probing Adenosine Recognition Sites by Using Dynamic Combinatorial Chemistry Chembiochem, 10, 2009
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3RBH
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![BU of 3rbh by Molmil](/molmil-images/mine/3rbh) | Structure of alginate export protein AlgE from Pseudomonas aeruginosa | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,2-ETHANEDIOL, Alginate production protein AlgE, ... | Authors: | Whitney, J.C, Hay, I.D, Li, C, Eckford, P.D, Robinson, H, Amaya, M.F, Wood, L.F, Ohman, D.E, Bear, C.E, Rehm, B.H, Howell, P.L. | Deposit date: | 2011-03-29 | Release date: | 2011-07-27 | Last modified: | 2011-08-24 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structural basis for alginate secretion across the bacterial outer membrane. Proc.Natl.Acad.Sci.USA, 108, 2011
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3RV1
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![BU of 3rv1 by Molmil](/molmil-images/mine/3rv1) | Crystal structure of the N-terminal and RNase III domains of K. polysporus Dcr1 E224Q mutant | Descriptor: | K. polysporus Dcr1 | Authors: | Nakanishi, K, Weinberg, D.E, Bartel, D.P, Patel, D.J. | Deposit date: | 2011-05-05 | Release date: | 2011-08-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.975 Å) | Cite: | The inside-out mechanism of dicers from budding yeasts. Cell(Cambridge,Mass.), 146, 2011
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3RW9
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![BU of 3rw9 by Molmil](/molmil-images/mine/3rw9) | Crystal Structure of human Spermidine Synthase in Complex with decarboxylated S-adenosylhomocysteine | Descriptor: | 5'-S-(3-aminopropyl)-5'-thioadenosine, Spermidine synthase | Authors: | Seckute, J, McCloskey, D.E, Thomas, H.J, Secrist III, J.A, Pegg, A.E, Ealick, S.E. | Deposit date: | 2011-05-08 | Release date: | 2011-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Binding and inhibition of human spermidine synthase by decarboxylated S-adenosylhomocysteine. Protein Sci., 20, 2011
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3IYP
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![BU of 3iyp by Molmil](/molmil-images/mine/3iyp) | The Interaction of Decay-accelerating Factor with Echovirus 7 | Descriptor: | Capsid protein, Complement decay-accelerating factor, LAURIC ACID, ... | Authors: | Plevka, P, Hafenstein, S, Zhang, Y, Harris, K.G, Cifuente, J.O, Bowman, V.D, Chipman, P.R, Lin, F, Medof, D.E, Bator, C.M, Rossmann, M.G. | Deposit date: | 2010-04-07 | Release date: | 2010-11-24 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (7.2 Å) | Cite: | Interaction of decay-accelerating factor with echovirus 7. J.Virol., 84, 2010
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3JCR
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![BU of 3jcr by Molmil](/molmil-images/mine/3jcr) | 3D structure determination of the human*U4/U6.U5* tri-snRNP complex | Descriptor: | LSm2, LSm3, LSm4, ... | Authors: | Agafonov, D.E, Kastner, B, Dybkov, O, Hofele, R.V, Liu, W.T, Urlaub, H, Luhrmann, R, Stark, H. | Deposit date: | 2016-01-21 | Release date: | 2016-03-09 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Molecular architecture of the human U4/U6.U5 tri-snRNP. Science, 351, 2016
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3RV0
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![BU of 3rv0 by Molmil](/molmil-images/mine/3rv0) | Crystal structure of K. polysporus Dcr1 without the C-terminal dsRBD | Descriptor: | K. polysporus Dcr1, MAGNESIUM ION | Authors: | Nakanishi, K, Weinberg, D.E, Bartel, D.P, Patel, D.J. | Deposit date: | 2011-05-05 | Release date: | 2011-08-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | The inside-out mechanism of dicers from budding yeasts. Cell(Cambridge,Mass.), 146, 2011
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2YM1
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![BU of 2ym1 by Molmil](/molmil-images/mine/2ym1) | SNAPSHOTS OF ENZYMATIC BAEYER-VILLIGER CATALYSIS: OXYGEN ACTIVATION AND INTERMEDIATE STABILIZATION: Arg337Lys MUTANT IN COMPLEX WITH NADP | Descriptor: | DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Orru, R, Dudek, H.M, Martinoli, C, Torres Pazmino, D.E, Royant, A, Weik, M, Fraaije, M.W, Mattevi, A. | Deposit date: | 2011-06-06 | Release date: | 2011-06-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Snapshots of Enzymatic Baeyer-Villiger Catalysis: Oxygen Activation and Intermediate Stabilization. J.Biol.Chem., 286, 2011
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2Y7X
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![BU of 2y7x by Molmil](/molmil-images/mine/2y7x) | The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs | Descriptor: | 6-CHLORO-N-[(3S)-1-(5-FLUORO-1,2,3,4-TETRAHYDROISOQUINOLIN-6-YL)-2-OXO-PYRROLIDIN-3-YL]NAPHTHALENE-2-SULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ... | Authors: | Watson, N.S, Adams, C, Belton, D, Brown, D, Burns-Kurtis, C.L, Chaudry, L, Chan, C, Convery, M.A, Davies, D.E, Exall, A.M, Harling, J.D, Irving, W.R, Irvine, S, Kleanthous, S, McLay, I.M, Pateman, A.J, Patikis, A.N, Roethka, T.J, Senger, S, Stelman, G.J, Toomey, J.R, West, R.I, Whittaker, C, Zhou, P, Young, R.J. | Deposit date: | 2011-02-02 | Release date: | 2011-03-16 | Last modified: | 2017-06-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Discovery of Potent and Long-Acting Oral Factor Xa Inhibitors with Tetrahydroisoquinoline and Benzazepine P4 Motifs. Bioorg.Med.Chem.Lett., 21, 2011
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2YLS
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![BU of 2yls by Molmil](/molmil-images/mine/2yls) | SNAPSHOTS OF ENZYMATIC BAEYER-VILLIGER CATALYSIS: OXYGEN ACTIVATION AND INTERMEDIATE STABILIZATION: REDUCED ENZYME BOUND TO NADP | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHENYLACETONE MONOOXYGENASE | Authors: | Orru, R, Dudek, H.M, Martinoli, C, Torres Pazmino, D.E, Royant, A, Weik, M, Fraaije, M.W, Mattevi, A. | Deposit date: | 2011-06-06 | Release date: | 2011-06-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Snapshots of Enzymatic Baeyer-Villiger Catalysis: Oxygen Activation and Intermediate Stabilization. J.Biol.Chem., 286, 2011
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