5TVN
Crystal structure of the LSD-bound 5-HT2B receptor
Summary for 5TVN
Entry DOI | 10.2210/pdb5tvn/pdb |
Descriptor | Chimera protein of human 5-hydroxytryptamine receptor 2B and E. Coli soluble cytochrome b562, (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, CHOLESTEROL, ... (7 entities in total) |
Functional Keywords | lsd, gpcr, serotonin receptor, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 46500.73 |
Authors | Wacker, D.,Wang, S.,McCorvy, J.D.,Betz, R.M.,Venkatakrishnan, A.J.,Levit, A.,Lansu, K.,Schools, Z.L.,Che, T.,Nichols, D.E.,Shoichet, B.K.,Dror, R.O.,Roth, B.L. (deposition date: 2016-11-09, release date: 2017-02-01, Last modification date: 2023-10-18) |
Primary citation | Wacker, D.,Wang, S.,McCorvy, J.D.,Betz, R.M.,Venkatakrishnan, A.J.,Levit, A.,Lansu, K.,Schools, Z.L.,Che, T.,Nichols, D.E.,Shoichet, B.K.,Dror, R.O.,Roth, B.L. Crystal Structure of an LSD-Bound Human Serotonin Receptor. Cell, 168:377-389.e12, 2017 Cited by PubMed: 28129538DOI: 10.1016/j.cell.2016.12.033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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