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PDB: 22297 results

3IYQ
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BU of 3iyq by Molmil
tmRNA-SmpB: a journey to the center of the bacterial ribosome
Descriptor: SsrA-binding protein, tmRNA
Authors:Weis, F, Bron, P, Giudice, E, Rolland, J.P, Thomas, D, Felden, B, Gillet, R.
Deposit date:2010-04-16
Release date:2010-10-20
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (13 Å)
Cite:tmRNA-SmpB: a journey to the centre of the bacterial ribosome.
Embo J., 29, 2010
3IV1
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BU of 3iv1 by Molmil
Coiled-coil domain of tumor susceptibility gene 101
Descriptor: CHLORIDE ION, SULFATE ION, Tumor susceptibility gene 101 protein
Authors:Neculai, D, Avvakumov, G.V, Wernimont, A.K, Xue, S, Walker, J.R, Li, Y, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2009-08-31
Release date:2009-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Coiled-Coil Domain of Human Tsg101
To be Published
6FM3
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BU of 6fm3 by Molmil
Deoxyguanylosuccinate synthase (DgsS) structure with ADP at 1.9 Angstrom resolution
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Adenylosuccinate synthetase, CHLORIDE ION
Authors:Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A.
Deposit date:2018-01-30
Release date:2019-06-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP0, dGMP, Magnesium at 2.3 Angstrom resolution
To Be Published
6TM5
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BU of 6tm5 by Molmil
Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Nek2A substrate at 3.9 angstrom resolution
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:Alfieri, C, Barford, D.
Deposit date:2019-12-03
Release date:2020-02-19
Last modified:2020-06-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase.
Embo Rep., 21, 2020
6FZO
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BU of 6fzo by Molmil
SMURFP-Y56F mutant
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ...
Authors:Janowski, R, Fuenzalida-Wernera, J.P, Mishra, K, Vetschera, P, Weidenfeld, I, Richter, K, Niessing, D, Ntziachristos, V, Stiel, A.C.
Deposit date:2018-03-15
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a biliverdin-bound phycobiliprotein: Interdependence of oligomerization and chromophorylation.
J. Struct. Biol., 204, 2018
6FOX
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BU of 6fox by Molmil
The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with kynurenine
Descriptor: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Levy, C.W, Leys, D.
Deposit date:2018-02-08
Release date:2019-08-21
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites.
Commun Biol, 2, 2019
3IYS
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BU of 3iys by Molmil
Homology model of avian polyomavirus asymmetric unit
Descriptor: Major capsid protein VP1
Authors:Shen, P.S, Enderlein, D, Nelson, C.D.S, Carter, W.S, Kawano, M, Xing, L, Swenson, R.D, Olson, N.H, Baker, T.S, Cheng, R.H, Atwood, W.J, Johne, R, Belnap, D.M.
Deposit date:2010-04-19
Release date:2011-01-26
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (11.3 Å)
Cite:The structure of avian polyomavirus reveals variably sized capsids, non-conserved inter-capsomere interactions, and a possible location of the minor capsid protein VP4.
Virology, 411, 2011
6FPB
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BU of 6fpb by Molmil
Crystal structure of anti-mTFP1 DARPin 1238_G01 in space group I4
Descriptor: CHLORIDE ION, DARPin 1238_G01
Authors:Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T.
Deposit date:2018-02-09
Release date:2018-10-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.617 Å)
Cite:DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
6RW3
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BU of 6rw3 by Molmil
The molecular basis for sugar import in malaria parasites.
Descriptor: Hexose transporter 1, alpha-D-glucopyranose, beta-D-glucopyranose
Authors:Qureshi, A, Matsuoka, R, Brock, J, Drew, D.
Deposit date:2019-06-03
Release date:2020-01-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:The molecular basis for sugar import in malaria parasites.
Nature, 578, 2020
3J02
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BU of 3j02 by Molmil
Lidless D386A Mm-cpn in the pre-hydrolysis ATP-bound state
Descriptor: Lidless D386A Mm-cpn variant
Authors:Zhang, J, Ma, B, DiMaio, F, Douglas, N.R, Joachimiak, L, Baker, D, Frydman, J, Levitt, M, Chiu, W.
Deposit date:2011-02-10
Release date:2011-05-18
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure.
Structure, 19, 2011
6FQH
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BU of 6fqh by Molmil
GluA2(flop) S729C ligand binding core dimer bound to NBQX at 1.76 Angstrom resolution
Descriptor: 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, Glutamate receptor 2,Glutamate receptor 2
Authors:Coombs, I.D, Soto, D, Gold, M.G, Farrant, M.F, Cull-Candy, S.G.
Deposit date:2018-02-14
Release date:2019-03-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.75940013 Å)
Cite:Homomeric GluA2(R) AMPA receptors can conduct when desensitized.
Nat Commun, 10, 2019
6FS0
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BU of 6fs0 by Molmil
INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN FABCOMPLEX IN COMPLEX WITH AZD5991
Descriptor: AZD5991, Fab Heavy Chain, Fab Light Chain, ...
Authors:Hargreaves, D.
Deposit date:2018-02-18
Release date:2018-12-26
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia.
Nat Commun, 9, 2018
6FSA
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BU of 6fsa by Molmil
Beta-Cardiac myosin post-rigor
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, FORMIC ACID, ...
Authors:Robert-Paganin, J, Auguin, D, Houdusse, A.
Deposit date:2018-02-19
Release date:2018-07-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Hypertrophic cardiomyopathy disease results from disparate impairments of cardiac myosin function and auto-inhibition.
Nat Commun, 9, 2018
3IXV
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BU of 3ixv by Molmil
Scorpion Hemocyanin resting state pseudo atomic model built based on cryo-EM density map
Descriptor: Hemocyanin AA6 chain
Authors:Cong, Y, Zhang, Q, Woolford, D, Schweikardt, T, Khant, H, Ludtke, S, Chiu, W, Decker, H.
Deposit date:2009-02-13
Release date:2009-06-02
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Structural Mechanism of SDS-Induced Enzyme Activity of Scorpion Hemocyanin Revealed by Electron Cryomicroscopy.
Structure, 17, 2009
6RH5
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BU of 6rh5 by Molmil
Solution structure and 1H, 13C and 15N chemical shift assignments for NECAP1 PHear domain
Descriptor: Adaptin ear-binding coat-associated protein 1
Authors:Owen, D.J, Neuhaus, D, Yang, J.-C, Herrmann, T.
Deposit date:2019-04-18
Release date:2019-09-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
3IW1
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BU of 3iw1 by Molmil
Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125 in complex with androstenedione
Descriptor: 4-ANDROSTENE-3-17-DIONE, Cytochrome P450 CYP125, PROTOPORPHYRIN IX CONTAINING FE
Authors:McLean, K.J, Levy, C, Munro, A.W, Leys, D.
Deposit date:2009-09-02
Release date:2009-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection.
J.Biol.Chem., 284, 2009
3IWK
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BU of 3iwk by Molmil
Crystal structure of aminoaldehyde dehydrogenase 1 from Pisum sativum (PsAMADH1)
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, Aminoaldehyde dehydrogenase, GLYCEROL, ...
Authors:Kopecny, D, Morera, S, Briozzo, P.
Deposit date:2009-09-02
Release date:2010-01-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional characterization of plant aminoaldehyde dehydrogenase from Pisum sativum with a broad specificity for natural and synthetic aminoaldehydes.
J.Mol.Biol., 396, 2010
3IXW
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BU of 3ixw by Molmil
Scorpion Hemocyanin activated state pseudo atomic model built based on cryo-EM density map
Descriptor: Hemocyanin AA6 chain
Authors:Cong, Y, Zhang, Q, Woolford, D, Schweikardt, T, Khant, H, Ludtke, S, Chiu, W, Decker, H.
Deposit date:2009-02-13
Release date:2009-06-02
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structural Mechanism of SDS-Induced Enzyme Activity of Scorpion Hemocyanin Revealed by Electron Cryomicroscopy.
Structure, 17, 2009
6FNH
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BU of 6fnh by Molmil
Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with a pyrazolo[3,4-d]pyrimidine fragment of NVP-BHG712
Descriptor: 1,2-ETHANEDIOL, 1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-amine, Ephrin type-A receptor 2
Authors:Kudlinzki, D, Troester, A, Witt, K, Linhard, V.L, Gande, S.L, Saxena, K, Schwalbe, H.
Deposit date:2018-02-04
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.379 Å)
Cite:NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
ChemMedChem, 13, 2018
6FNW
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BU of 6fnw by Molmil
Structure of a volume-regulated anion channel of the LRRC8 family
Descriptor: 1,2-ETHANEDIOL, Volume-regulated anion channel subunit LRRC8A
Authors:Deneka, D, Sawicka, M, Lam, A.K.M, Paulino, C, Dutzler, R.
Deposit date:2018-02-05
Release date:2018-05-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018
6FOZ
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BU of 6foz by Molmil
The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 13
Descriptor: 5-(3,4-dichlorophenyl)furan-2-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
Authors:Levy, C.W, Leys, D.
Deposit date:2018-02-08
Release date:2019-08-21
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites.
Commun Biol, 2, 2019
6FQB
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BU of 6fqb by Molmil
MurT/GatD peptidoglycan amidotransferase complex from Streptococcus pneumoniae R6
Descriptor: Cobyric acid synthase, GLUTAMINE, Mur ligase family protein
Authors:Morlot, C, Contreras-Martel, C, Leisico, F, Straume, D, Peters, K, Hegnar, O.A, Simon, N, Villard, A.M, Breukink, E, Gravier-Pelletier, C, Le Corre, L, Vollmer, W, Pietrancosta, N, Havarstein, L.S, Zapun, A.
Deposit date:2018-02-13
Release date:2018-08-22
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae.
Nat Commun, 9, 2018
6RKC
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BU of 6rkc by Molmil
Inter-dimeric interface controls function and stability of S-methionine adenosyltransferase from U. urealiticum
Descriptor: (DIPHOSPHONO)AMINOPHOSPHONIC ACID, MAGNESIUM ION, Methionine adenosyltransferase, ...
Authors:Shahar, A, Zarivach, R, Bershtein, S, Kleiner, D, Shmulevich, F.
Deposit date:2019-04-30
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:The interdimeric interface controls function and stability of Ureaplasma urealiticum methionine S-adenosyltransferase.
J.Mol.Biol., 431, 2019
3L8P
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BU of 3l8p by Molmil
Crystal structure of cytoplasmic kinase domain of Tie2 complexed with inhibitor CEP11207
Descriptor: 2-methyl-11-(1-methylethyl)-8-[(2S)-tetrahydro-2H-pyran-2-yl]-2,11,12,13-tetrahydro-4H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, Angiopoietin-1 receptor
Authors:Fedorov, A.A, Fedorov, E.V, Pauletti, D, Meyer, S.L, Hudkins, R.L, Almo, S.C.
Deposit date:2010-01-03
Release date:2010-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of cytoplasmic kinase domain of Tie2 complexed with inhibitor CEP11207
To be Published
3L8Y
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BU of 3l8y by Molmil
Complex of Ras with cyclen
Descriptor: 1,4,7,10-tetraazacyclododecane, CALCIUM ION, GTPase HRas, ...
Authors:Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R.
Deposit date:2010-01-04
Release date:2011-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes
Angew.Chem.Int.Ed.Engl., 49, 2010

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