3IW1
Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125 in complex with androstenedione
Summary for 3IW1
Entry DOI | 10.2210/pdb3iw1/pdb |
Related | 2IW2 3IVY 3IW0 |
Descriptor | Cytochrome P450 CYP125, 4-ANDROSTENE-3-17-DIONE, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total) |
Functional Keywords | androstenedione, cholesterol, monoxygenase, tuberculosis, cytochrome p450, heme, iron, metal-binding, monooxygenase, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 49394.39 |
Authors | McLean, K.J.,Levy, C.,Munro, A.W.,Leys, D. (deposition date: 2009-09-02, release date: 2009-11-03, Last modification date: 2023-09-06) |
Primary citation | McLean, K.J.,Lafite, P.,Levy, C.,Cheesman, M.R.,Mast, N.,Pikuleva, I.A.,Leys, D.,Munro, A.W. The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection. J.Biol.Chem., 284:35524-35533, 2009 Cited by PubMed: 19846552DOI: 10.1074/jbc.M109.032706 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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