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PDB: 22297 results

8CGG
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BU of 8cgg by Molmil
Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 2)
Descriptor: TAR DNA-binding protein 43
Authors:Arseni, D, Ryskeldi-Falcon, B.
Deposit date:2023-02-04
Release date:2023-08-02
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Nature, 620, 2023
5MQO
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BU of 5mqo by Molmil
Glycoside hydrolase BT_1003
Descriptor: Non-reducing end beta-L-arabinofuranosidase
Authors:Basle, A, Ndeh, D, Rogowski, A, Cartmell, A, Luis, A.S, Venditto, I, Labourel, A, Gilbert, H.J.
Deposit date:2016-12-20
Release date:2017-03-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Complex pectin metabolism by gut bacteria reveals novel catalytic functions.
Nature, 544, 2017
8CGH
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Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 3)
Descriptor: TAR DNA-binding protein 43
Authors:Arseni, D, Ryskeldi-Falcon, B.
Deposit date:2023-02-04
Release date:2023-08-02
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Nature, 620, 2023
7A0R
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BU of 7a0r by Molmil
50S Deinococcus radiodurans ribosome bounded with mycinamicin I
Descriptor: 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, ...
Authors:Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A.
Deposit date:2020-08-10
Release date:2021-08-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.
Nucleic Acids Res., 49, 2021
7A18
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BU of 7a18 by Molmil
50S Deinococcus radiodurans ribosome bounded with mycinamicin IV
Descriptor: 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, ...
Authors:Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A.
Deposit date:2020-08-12
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.
Nucleic Acids Res., 49, 2021
8CEF
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BU of 8cef by Molmil
Asymmetric Dimerization in a Transcription Factor Superfamily is Promoted by Allosteric Interactions with DNA
Descriptor: DNA (26-MER), Nuclear receptor DNA binding domain, ZINC ION
Authors:Patel, A.K.M, Shaik, T.B, McEwen, A.G, Moras, D, Klaholz, B.P, Billas, I.M.L.
Deposit date:2023-02-01
Release date:2023-08-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.486 Å)
Cite:Asymmetric dimerization in a transcription factor superfamily is promoted by allosteric interactions with DNA.
Nucleic Acids Res., 51, 2023
5MN8
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BU of 5mn8 by Molmil
S. aureus FtsZ 12-316 F138A GTP Closed form (5FCm)
Descriptor: Cell division protein FtsZ, GUANOSINE-5'-TRIPHOSPHATE
Authors:Wagstaff, J.M, Tsim, M, Kureisaite-Ciziene, D, Lowe, J.
Deposit date:2016-12-12
Release date:2017-01-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:A Polymerization-Associated Structural Switch in FtsZ That Enables Treadmilling of Model Filaments.
MBio, 8, 2017
6ZSN
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BU of 6zsn by Molmil
Crystal structure of rsGCaMP double mutant Ile80His/Val116Ile in the OFF state (illuminated)
Descriptor: CALCIUM ION, FORMIC ACID, Green fluorescent protein,Green fluorescent protein,Calmodulin, ...
Authors:Janowski, R, Fuenzalida-Werner, J.P, Mishra, K, Stiel, A.C, Niessing, D.
Deposit date:2020-07-16
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Genetically encoded photo-switchable molecular sensors for optoacoustic and super-resolution imaging.
Nat.Biotechnol., 40, 2022
6ZSM
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BU of 6zsm by Molmil
Crystal structure of rsGCaMP double mutant Ile80His/Val116Ile in the ON state (non-illuminated)
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, FORMIC ACID, ...
Authors:Janowski, R, Fuenzalida-Werner, J.P, Mishra, K, Stiel, A.C, Niessing, D.
Deposit date:2020-07-16
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Genetically encoded photo-switchable molecular sensors for optoacoustic and super-resolution imaging.
Nat.Biotechnol., 40, 2022
5MBS
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BU of 5mbs by Molmil
Crystal structure of Bacillus subtilis EngA in space group P21
Descriptor: GTPase Der, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION
Authors:da Silveira Tome, C, Foucher, A.E, Jault, J.M, Housset, D.
Deposit date:2016-11-08
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of Bacillus subtilis EngA in space group P21
To Be Published
8C2H
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BU of 8c2h by Molmil
Transmembrane domain of active state homomeric GluA1 AMPA receptor in tandem with TARP gamma 3
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Glutamate receptor 1 flip isoform, ...
Authors:Zhang, D, Ivica, J, Krieger, J.M, Ho, H, Yamashita, K, Cais, O, Greger, I.
Deposit date:2022-12-22
Release date:2023-08-30
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8C1P
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BU of 8c1p by Molmil
Active state homomeric GluA1 AMPA receptor in complex with TARP gamma 3
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CYCLOTHIAZIDE, ...
Authors:Zhang, D, Ivica, J, Krieger, J.M, Ho, H, Yamashita, K, Cais, O, Greger, I.
Deposit date:2022-12-21
Release date:2023-08-30
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
5MPZ
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BU of 5mpz by Molmil
Crystal structure of CREBBP bromodomain complexed with CBP007
Descriptor: CREB-binding protein, methyl 2-oxidanylidene-3~{H}-1,3-benzoxazole-6-carboxylate
Authors:Zhu, J, Spiliotopoulos, D, Caflisch, A.
Deposit date:2016-12-19
Release date:2017-05-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain.
Bioorg. Med. Chem. Lett., 27, 2017
8CIJ
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BU of 8cij by Molmil
CRYSTAL STRUCTURE OF HUMAN HPK1 (MAP4K1) COMPLEX WITH 2-[8-Amino-7-fluoro-6-(8-methyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-7-yl)-isoquinolin-3-ylamino]-6-isopropyl-5,6-dihydro-4H-1,6,8a-triaza-azulen-7-one
Descriptor: 2-[[8-azanyl-7-fluoranyl-6-(8-methyl-2,3-dihydro-1~{H}-pyrido[2,3-b][1,4]oxazin-7-yl)isoquinolin-3-yl]amino]-6-propan-2-yl-5,8-dihydro-4~{H}-pyrazolo[1,5-d][1,4]diazepin-7-one, Mitogen-activated protein kinase kinase kinase kinase 1
Authors:Musil, D, Toure, M.
Deposit date:2023-02-09
Release date:2023-08-16
Method:X-RAY DIFFRACTION (2.821 Å)
Cite:Discovery of quinazoline HPK1 inhibitors with high cellular potency.
Bioorg.Med.Chem., 92, 2023
8C36
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BU of 8c36 by Molmil
Light-adapted 2.0 Angstrom crystal structure of H132A variant of cobalamin binding domain belonging to a light-dependent transcription regulator TtCarH obtained under aerobic conditions
Descriptor: COBALAMIN, Probable transcriptional regulator
Authors:Poddar, H, Leys, D.
Deposit date:2022-12-23
Release date:2023-08-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Redox driven B 12 -ligand switch drives CarH photoresponse.
Nat Commun, 14, 2023
8C1S
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BU of 8c1s by Molmil
Transmembrane domain of resting state homomeric GluA2 F231A mutant AMPA receptor in complex with TARP gamma 2
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Glutamate receptor 2, ...
Authors:Zhang, D, Ivica, J, Krieger, J.M, Ho, H, Yamashita, K, Cais, O, Greger, I.
Deposit date:2022-12-21
Release date:2023-08-30
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8C2I
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BU of 8c2i by Molmil
Transmembrane domain of resting state homomeric GluA1 AMPA receptor in complex with TARP gamma 3
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Glutamate receptor 1 flip isoform, ...
Authors:Zhang, D, Ivica, J, Krieger, J.M, Ho, H, Yamashita, K, Cais, O, Greger, I.
Deposit date:2022-12-22
Release date:2023-08-30
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
5MGK
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BU of 5mgk by Molmil
Crystal Structure of BAZ2A bromodomain in complex with 4-propionyl-pyrrole derivative 2
Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, methyl 4-propanoyl-1~{H}-pyrrole-2-carboxylate
Authors:Lolli, G, Spiliotopoulos, D, Caflisch, A.
Deposit date:2016-11-21
Release date:2017-04-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Discovery of BAZ2A bromodomain ligands.
Eur J Med Chem, 139, 2017
8C1R
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BU of 8c1r by Molmil
Resting state homomeric GluA2 F231A mutant AMPA receptor in complex with TARP gamma-2
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Glutamate receptor 2, ...
Authors:Zhang, D, Ivica, J, Krieger, J.M, Ho, H, Yamashita, K, Cais, O, Greger, I.
Deposit date:2022-12-21
Release date:2023-08-30
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8C34
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BU of 8c34 by Molmil
Aerobic light exposed 1.8 Angstrom crystal structure of cobalamin binding domain belonging to a light-dependent transcription regulator TtCarH
Descriptor: COBALAMIN, DI(HYDROXYETHYL)ETHER, Probable transcriptional regulator, ...
Authors:Poddar, H, Leys, D.
Deposit date:2022-12-23
Release date:2023-08-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Redox driven B 12 -ligand switch drives CarH photoresponse.
Nat Commun, 14, 2023
8C1Q
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BU of 8c1q by Molmil
Resting state homomeric GluA1 AMPA receptor in complex with TARP gamma 3
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Glutamate receptor 1 flip isoform, ...
Authors:Zhang, D, Ivica, J, Krieger, J.M, Ho, H, Yamashita, K, Cais, O, Greger, I.
Deposit date:2022-12-21
Release date:2023-08-30
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8C35
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BU of 8c35 by Molmil
Dark state 2.1 Angstrom crystal structure of H132A variant of cobalamin binding domain belonging to a light-dependent transcription regulator TtCarH
Descriptor: 5'-DEOXYADENOSINE, COBALAMIN, Probable transcriptional regulator
Authors:Poddar, H, Leys, D.
Deposit date:2022-12-23
Release date:2023-08-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Redox driven B 12 -ligand switch drives CarH photoresponse.
Nat Commun, 14, 2023
4Q9B
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BU of 4q9b by Molmil
IgNAR antibody domain C2
Descriptor: Novel antigen receptor
Authors:Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J.
Deposit date:2014-04-30
Release date:2014-07-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
Proc.Natl.Acad.Sci.USA, 111, 2014
5MK1
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BU of 5mk1 by Molmil
Crystal structure of the His Domain Protein Tyrosine Phosphatase (HD-PTP/PTPN23) Bro1 domain (CHMP4A peptide complex structure)
Descriptor: Charged multivesicular body protein 4a, Tyrosine-protein phosphatase non-receptor type 23
Authors:Levy, C, Gahloth, D.
Deposit date:2016-12-02
Release date:2017-08-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Specific Interaction of TGF beta Signaling Regulators SARA/Endofin with HD-PTP.
Structure, 25, 2017
8C32
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BU of 8c32 by Molmil
Dark state 2.2 Angstrom crystal structure of cobalamin binding domain belonging to a light-dependent transcription regulator TtCarH obtained under anaerobic condition
Descriptor: 5'-DEOXYADENOSINE, BROMIDE ION, COBALAMIN, ...
Authors:Poddar, H, Leys, D.
Deposit date:2022-12-23
Release date:2023-08-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Redox driven B 12 -ligand switch drives CarH photoresponse.
Nat Commun, 14, 2023

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