8C1R

Resting state homomeric GluA2 F231A mutant AMPA receptor in complex with TARP gamma-2

Summary for 8C1R

• Entry DOI: 10.2210/pdb8c1r/pdb
• EMDB information: 16381
• Descriptor: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, ... (7 entities in total)
• Functional Keywords: ampar, ion channels, neurotransmission, membrane protein
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 8
• Total formula weight: 551412.31

Authors

Zhang, D.,Ivica, J.,Krieger, J.M.,Ho, H.,Yamashita, K.,Cais, O.,Greger, I. (deposition date: 2022-12-21, release date: 2023-08-30, Last modification date: 2023-10-11)

• Primary citation: Zhang, D.,Ivica, J.,Krieger, J.M.,Ho, H.,Yamashita, K.,Stockwell, I.,Baradaran, R.,Cais, O.,Greger, I.H.; Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.; Nature, 621:877-882, 2023; PubMed: 37704721; DOI: 10.1038/s41586-023-06528-0

Experimental method

ELECTRON MICROSCOPY (3.2 Å)