8C1R
Resting state homomeric GluA2 F231A mutant AMPA receptor in complex with TARP gamma-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutamate receptor 2 | polymer | 891 | 99880.9 | 4 | UniProt (P19491) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
| 2 | E, F, G, H (E, F, G, H) | Voltage-dependent calcium channel gamma-2 subunit | polymer | 322 | 35807.6 | 4 | UniProt (Q71RJ2) Pfam (PF00822) | Rattus norvegicus (Norway rat) | Neuronal voltage-gated calcium channel gamma-2 subunit,Stargazin,Transmembrane AMPAR regulatory protein gamma-2,TARP gamma-2 |
| 3 | I, M, Q, T (A, B, C, D) | {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | non-polymer | 409.3 | 4 | Chemie (ZK1) | |||
| 4 | J, L, N, S, U... (A, B, C, D, F...) | PALMITIC ACID | non-polymer | 256.4 | 7 | Chemie (PLM) | |||
| 5 | K, O, R, V (A, B, C, D) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 4 | Chemie (OLC) | |||
| 6 | AA, BA, P, W, X (G, B, D, E) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 5 | Chemie (POV) | |||
| 7 | CA, DA, EA, FA (A, C, D, G) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A, B, C, D: -28 - 862 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Asp -7 | - | insertion |
| Tyr -6 | - | insertion |
| Lys -5 | - | insertion |
| Asp -4 | - | insertion |
| Asp -3 | - | insertion |
| Asp -2 | - | insertion |
| Asp -1 | - | insertion |
| Lys 0 | - | insertion |
| Arg 586 | Gln 607 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 542753.8 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 8658.5 | |
| All* | Total formula weight | 551412.3 |
