4AAQ
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![BU of 4aaq by Molmil](/molmil-images/mine/4aaq) | ATP-triggered molecular mechanics of the chaperonin GroEL | Descriptor: | 60 KDA CHAPERONIN, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Clare, D.K, Vasishtan, D, Stagg, S, Quispe, J, Farr, G.W, Topf, M, Horwich, A.L, Saibil, H.R. | Deposit date: | 2011-12-05 | Release date: | 2012-12-12 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the Groel Chaperonin. Cell(Cambridge,Mass.), 149, 2012
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4A93
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![BU of 4a93 by Molmil](/molmil-images/mine/4a93) | RNA Polymerase II elongation complex containing a CPD Lesion | Descriptor: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*T*TTP*TP*TP*CP*C BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP*AP)-3', ... | Authors: | Walmacq, C, Cheung, A.C.M, Kireeva, M.L, Lubkowska, L, Ye, C, Gotte, D, Strathern, J.N, Carell, T, Cramer, P, Kashlev, M. | Deposit date: | 2011-11-23 | Release date: | 2012-03-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage. Mol.Cell, 46, 2012
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2KG4
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![BU of 2kg4 by Molmil](/molmil-images/mine/2kg4) | Three-dimensional structure of human Gadd45alpha in solution by NMR | Descriptor: | Growth arrest and DNA-damage-inducible protein GADD45 alpha | Authors: | Sanchez, R, Pantoja-Uceda, D, Prieto, J, Diercks, T, Campos-Olivas, R, Blanco, F.J. | Deposit date: | 2009-03-04 | Release date: | 2009-03-31 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase J.Biol.Chem., 285, 2010
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3DWC
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![BU of 3dwc by Molmil](/molmil-images/mine/3dwc) | Trypanosoma Cruzi Metallocarboxypeptidase 1 | Descriptor: | ALANINE, COBALT (II) ION, GLYCEROL, ... | Authors: | Niemirowicz, G, Fernandez, D, Sola, M, Cazzulo, J.J, Aviles, F.X, Gomis-Ruth, F.X. | Deposit date: | 2008-07-22 | Release date: | 2008-09-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The molecular analysis of Trypanosoma cruzi metallocarboxypeptidase 1 provides insight into fold and substrate specificity Mol.Microbiol., 70, 2008
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4AOJ
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![BU of 4aoj by Molmil](/molmil-images/mine/4aoj) | Human TrkA in complex with the inhibitor AZ-23 | Descriptor: | 5-chloranyl-N2-[(1S)-1-(5-fluoranylpyridin-2-yl)ethyl]-N4-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyrimidine-2,4-diamine, HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR, ZINC ION | Authors: | Wang, T, Lamb, M.L, Block, M.H, Davies, A.M, Han, Y, Hoffmann, E, Ioannidis, S, Josey, J.A, Liu, Z, Lyne, P.D, MacIntyre, T, Mohr, P.J, Omer, C.A, Sjogren, T, Thress, K, Wang, B, Wang, H, Yu, D, Zhang, H. | Deposit date: | 2012-03-28 | Release date: | 2012-08-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Discovery of Disubstituted Imidazo[4,5-B]Pyridines and Purines as Potent Trka Inhibitors Acs Med.Chem.Lett., 3, 2012
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5UJG
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![BU of 5ujg by Molmil](/molmil-images/mine/5ujg) | ovGRN12-35_3s | Descriptor: | Granulin | Authors: | Bansal, P, Smout, M, Wilson, D, Caceres, C.C, Dastpeyman, M, Sotillo, J, Seifert, J, Brindley, P, Loukas, A, Daly, N. | Deposit date: | 2017-01-17 | Release date: | 2018-01-24 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Development of a Potent Wound Healing Agent Based on the Liver Fluke Granulin Structural Fold. J. Med. Chem., 60, 2017
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3SI2
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![BU of 3si2 by Molmil](/molmil-images/mine/3si2) | Structure of glycosylated murine glutaminyl cyclase in presence of the inhibitor PQ50 (PDBD150) | Descriptor: | 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Parthier, C, Carrillo, D, Stubbs, M.T. | Deposit date: | 2011-06-17 | Release date: | 2011-06-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of Glycosylated Mammalian Glutaminyl Cyclases Reveal Conformational Variability near the Active Center. Biochemistry, 50, 2011
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5UJN
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4AR7
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![BU of 4ar7 by Molmil](/molmil-images/mine/4ar7) | X-ray structure of the cyan fluorescent protein mTurquoise | Descriptor: | GREEN FLUORESCENT PROTEIN | Authors: | von Stetten, D, Noirclerc-Savoye, M, Goedhart, J, Gadella, T.W.J, Royant, A. | Deposit date: | 2012-04-21 | Release date: | 2012-08-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | Structure of a Fluorescent Protein from Aequorea Victoria Bearing the Obligate-Monomer Mutation A206K. Acta Crystallogr.,Sect.F, 68, 2012
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2K71
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![BU of 2k71 by Molmil](/molmil-images/mine/2k71) | Structure and dynamics of a DNA GNRA hairpin solved vy high-sensitivity NMR with two independent converging methods, simulated annealing (DYANA) and mesoscopic molecular modelling (BCE/AMBER) | Descriptor: | 5'-D(*DGP*DCP*DGP*DAP*DAP*DAP*DGP*DC)-3' | Authors: | Santini, G.P.H, Cognet, J.A.H, Xu, D, Singarapu, K.K, Herve du Penhoat, C.L.M. | Deposit date: | 2008-07-29 | Release date: | 2009-07-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Nucleic acid folding determined by mesoscale modeling and NMR spectroscopy: solution structure of d(GCGAAAGC). J.Phys.Chem.B, 113, 2009
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4A4G
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![BU of 4a4g by Molmil](/molmil-images/mine/4a4g) | Solution structure of SMN Tudor domain in complex with asymmetrically dimethylated arginine | Descriptor: | NG,NG-DIMETHYL-L-ARGININE, SURVIVAL MOTOR NEURON PROTEIN | Authors: | Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M. | Deposit date: | 2011-10-12 | Release date: | 2011-11-30 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins Nat.Struct.Mol.Biol., 18, 2011
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5UP1
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![BU of 5up1 by Molmil](/molmil-images/mine/5up1) | Solution structure of the de novo mini protein EEHEE_rd3_1049 | Descriptor: | EEHEE_rd3_1049 | Authors: | Houliston, S, Rocklin, G.J, Lemak, A, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H. | Deposit date: | 2017-02-01 | Release date: | 2017-07-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Global analysis of protein folding using massively parallel design, synthesis, and testing. Science, 357, 2017
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3WXZ
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![BU of 3wxz by Molmil](/molmil-images/mine/3wxz) | The structure of the I375F mutant of CsyB | Descriptor: | Putative uncharacterized protein csyB | Authors: | Mori, T, Yang, D, Matsui, T, Morita, H, Fujii, I, Abe, I. | Deposit date: | 2014-08-13 | Release date: | 2015-01-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.303 Å) | Cite: | Structural basis for the formation of acylalkylpyrones from two beta-ketoacyl units by the fungal type III polyketide synthase CsyB. J.Biol.Chem., 290, 2015
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2KBF
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2H3S
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![BU of 2h3s by Molmil](/molmil-images/mine/2h3s) | cis-Azobenzene-avian pancreatic polypeptide bound to DPC micelles | Descriptor: | (3-{(Z)-[3-(AMINOMETHYL)PHENYL]DIAZENYL}PHENYL)ACETIC ACID, Pancreatic hormone | Authors: | Jurt, S, Aemissegger, A, Guentert, P, Zerbe, O, Hilvert, D. | Deposit date: | 2006-05-23 | Release date: | 2006-09-12 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | A Photoswitchable Miniprotein Based on the Sequence of Avian Pancreatic Polypeptide Angew.Chem.Int.Ed.Engl., 45, 2006
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8AY5
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![BU of 8ay5 by Molmil](/molmil-images/mine/8ay5) | Human rhinovirus 2 empty particle in situ | Descriptor: | Capsid protein VP1, Capsid protein VP2, VP3 | Authors: | Ishemgulova, A, Mukhamedova, L, Trebichalska, Z, Payne, P, Smerdova, L, Moravcova, J, Hrebik, D, Buchta, D, Skubnik, K, Fuzik, T, Novacek, J, Plevka, P. | Deposit date: | 2022-09-01 | Release date: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (7.1 Å) | Cite: | Endosome rupture enables enteroviruses to infect cells. To Be Published
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2HAF
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![BU of 2haf by Molmil](/molmil-images/mine/2haf) | Crystal structure of a putative translation repressor from Vibrio cholerae | Descriptor: | Putative translation repressor | Authors: | Sugadev, R, Seetharaman, J, Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2006-06-12 | Release date: | 2006-07-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Crystal structure of a putative translation repressor from Vibrio cholerae To be Published
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2HAM
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![BU of 2ham by Molmil](/molmil-images/mine/2ham) | Crystal structure of VDR LBD complexed to 2alpha-propyl-calcitriol | Descriptor: | 2ALPHA-PROPYL-1ALPHA,25-DIHYDROXYVITAMIN D3, Vitamin D3 receptor | Authors: | Hourai, S, Rochel, N, Moras, D. | Deposit date: | 2006-06-13 | Release date: | 2006-08-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing a Water Channel near the A-Ring of Receptor-Bound 1alpha,25-Dihydroxyvitamin D3 with Selected 2alpha-Substituted Analogues J.Med.Chem., 49, 2006
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8AY4
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![BU of 8ay4 by Molmil](/molmil-images/mine/8ay4) | Human rhinovirus 2 virion in situ | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Ishemgulova, A, Mukhamedova, L, Trebichalska, Z, Payne, P, Smerdova, L, Moravcova, J, Hrebik, D, Buchta, D, Skubnik, K, Fuzik, T, Novacek, J, Plevka, P. | Deposit date: | 2022-09-01 | Release date: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Endosome rupture enables enteroviruses to infect cells. To Be Published
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5VJO
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3DKZ
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![BU of 3dkz by Molmil](/molmil-images/mine/3dkz) | Crystal structure of the Q7W9W5_BORPA protein from Bordetella parapertussis. Northeast Structural Genomics Consortium target BpR208C. | Descriptor: | Thioesterase superfamily protein | Authors: | Vorobiev, S.M, Su, M, Seetharaman, J, Wang, D, Ciccosanti, C, Foote, E.L, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-06-26 | Release date: | 2008-08-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the Q7W9W5_BORPA protein from Bordetella parapertussis. To be Published
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5VKZ
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![BU of 5vkz by Molmil](/molmil-images/mine/5vkz) | Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies | Descriptor: | Mitochondrial distribution and morphology protein 12 | Authors: | Egea, P.F, AhYoung, A.P, Lu, B, Tan, H.R, Cascio, D. | Deposit date: | 2017-04-24 | Release date: | 2017-07-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies. Biochem. Biophys. Res. Commun., 488, 2017
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3DRF
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![BU of 3drf by Molmil](/molmil-images/mine/3drf) | Lactococcal OppA complexed with an endogenous peptide in the closed conformation | Descriptor: | Oligopeptide-binding protein oppA, endogenous peptide | Authors: | Berntsson, R.P.-A, Doeven, M.K, Duurkens, R.H, Sengupta, D, Marrink, S.-J, Thunnissen, A.-M, Poolman, B, Slotboom, D.-J. | Deposit date: | 2008-07-11 | Release date: | 2009-03-31 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | The structural basis for peptide selection by the transport receptor OppA Embo J., 28, 2009
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2GK3
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![BU of 2gk3 by Molmil](/molmil-images/mine/2gk3) | Cytoplasmic Protein STM3548 from Salmonella typhimurium | Descriptor: | GLYCEROL, putative cytoplasmic protein | Authors: | Petrova, T, Cuff, M.E, Wu, R.Y, Holzle, D, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-03-31 | Release date: | 2006-05-02 | Last modified: | 2011-08-03 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Novel hexamerization motif is discovered in a conserved cytoplasmic protein from Salmonella typhimurium. J.Struct.Funct.Genom., 8, 2007
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3X1I
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![BU of 3x1i by Molmil](/molmil-images/mine/3x1i) | hPPARgamma Ligand binding domain in complex with 6-oxo-tetracosahexaenoic acid | Descriptor: | (8E,12Z,15Z,18Z,21Z)-6-oxotetracosa-8,12,15,18,21-pentaenoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Egawa, D, Itoh, T, Yamamoto, K. | Deposit date: | 2014-11-18 | Release date: | 2015-04-08 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Characterization of covalent bond formation between PPAR gamma and oxo-fatty acids. Bioconjug.Chem., 26, 2015
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