3FV6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fv6 by Molmil](/molmil-images/mine/3fv6) | |
3G7S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g7s by Molmil](/molmil-images/mine/3g7s) | |
5TJ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5tj3 by Molmil](/molmil-images/mine/5tj3) | Crystal structure of wild type alkaline phosphatase PafA to 1.7A resolution | Descriptor: | Alkaline phosphatase PafA, ZINC ION | Authors: | Lyubimov, A.Y, Sunden, F, Ressl, S, Herschlag, D. | Deposit date: | 2016-10-03 | Release date: | 2016-11-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mechanistic and Evolutionary Insights from Comparative Enzymology of Phosphomonoesterases and Phosphodiesterases across the Alkaline Phosphatase Superfamily. J.Am.Chem.Soc., 138, 2016
|
|
2KLU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2klu by Molmil](/molmil-images/mine/2klu) | |
2KMP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kmp by Molmil](/molmil-images/mine/2kmp) | |
3FZ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fz7 by Molmil](/molmil-images/mine/3fz7) | |
2KK1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kk1 by Molmil](/molmil-images/mine/2kk1) | Solution structure of C-terminal Domain of Tyrosine-protein kinase ABL2 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) target HR5537A | Descriptor: | Tyrosine-protein kinase ABL2 | Authors: | Liu, G, Wang, D, Nwosu, C, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-06-14 | Release date: | 2009-08-11 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR structure of F-actin-binding domain of Arg/Abl2 from Homo sapiens. Proteins, 78, 2010
|
|
2KR0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kr0 by Molmil](/molmil-images/mine/2kr0) | |
3GCV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gcv by Molmil](/molmil-images/mine/3gcv) | Human P38 MAP Kinase in Complex with RL62 | Descriptor: | 1-{3-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(3-methylphenyl)-1H-pyrazol-5-yl]urea, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | Authors: | Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. | Deposit date: | 2009-02-22 | Release date: | 2009-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors. J.Am.Chem.Soc., 131, 2009
|
|
2K67
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2k67 by Molmil](/molmil-images/mine/2k67) | |
4A2O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4a2o by Molmil](/molmil-images/mine/4a2o) | STRUCTURE OF THE HUMAN EOSINOPHIL CATIONIC PROTEIN IN COMPLEX WITH SULFATE ANIONS | Descriptor: | EOSINOPHIL CATIONIC PROTEIN, SULFATE ION | Authors: | Boix, E, Pulido, D, Moussaoui, M, Nogues, V, Russi, S. | Deposit date: | 2011-09-28 | Release date: | 2012-06-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | The Sulfate-Binding Site Structure of the Human Eosinophil Cationic Protein as Revealed by a New Crystal Form. J.Struct.Biol., 179, 2012
|
|
4A38
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4a38 by Molmil](/molmil-images/mine/4a38) | METALLO-CARBOXYPEPTIDASE FROM PSEUDOMONAS AUREGINOSA IN COMPLEX WITH L-BENZYLSUCCINIC ACID | Descriptor: | L-BENZYLSUCCINIC ACID, METALLO-CARBOXYPEPTIDASE, ZINC ION | Authors: | Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D. | Deposit date: | 2011-09-30 | Release date: | 2012-05-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps. Faseb J., 26, 2012
|
|
3RK2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rk2 by Molmil](/molmil-images/mine/3rk2) | Truncated SNARE complex | Descriptor: | CALCIUM ION, Synaptosomal-associated protein 25, Syntaxin-1A, ... | Authors: | Kuemmel, D, Reinisch, K.M. | Deposit date: | 2011-04-17 | Release date: | 2011-07-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Complexin cross-links prefusion SNAREs into a zigzag array. Nat.Struct.Mol.Biol., 18, 2011
|
|
3G70
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g70 by Molmil](/molmil-images/mine/3g70) | Design and Preparation of Potent, Non-Peptidic, Bioavailable Renin Inhibitors | Descriptor: | (1R,5S)-7-{4-[3-(2-chloro-3,6-difluorophenoxy)propyl]phenyl}-N-cyclopropyl-N-(2,3-dichlorobenzyl)-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | Authors: | Bezencon, O, Bur, D, Prade, L, Weller, T, Boss, C, Fischli, W. | Deposit date: | 2009-02-09 | Release date: | 2009-06-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Design and Preparation of Potent, Nonpeptidic, Bioavailable Renin Inhibitors J.Med.Chem., 52, 2009
|
|
2HOR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hor by Molmil](/molmil-images/mine/2hor) | Crystal structure of alliinase from garlic- apo form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Alliin lyase 1, ... | Authors: | Shimon, L.J.W, Rabinkov, A, Wilcheck, M, Mirelman, D, Frolow, F. | Deposit date: | 2006-07-16 | Release date: | 2007-02-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Two Structures of Alliinase from Alliium sativum L.: Apo Form and Ternary Complex with Aminoacrylate Reaction Intermediate Covalently Bound to the PLP Cofactor. J.Mol.Biol., 366, 2007
|
|
417D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 417d by Molmil](/molmil-images/mine/417d) | A THYMINE-LIKE BASE ANALOGUE FORMS WOBBLE PAIRS WITH ADENINE | Descriptor: | DNA (5'-D(*CP*AP*CP*GP*(C46)P*G)-3') | Authors: | Lin, P.K.T, Schuerman, M.H, Moore, G.S, Van Meervelt, L, Loakes, D, Brown, D.M, Moore, M.H. | Deposit date: | 1998-07-15 | Release date: | 1998-09-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A thymine-like base analogue forms wobble pairs with adenine in a Z-DNA duplex. J.Mol.Biol., 282, 1998
|
|
3G9V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g9v by Molmil](/molmil-images/mine/3g9v) | Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22 | Descriptor: | Interleukin 22 receptor, alpha 2, Interleukin-22 | Authors: | de Moura, P.R, Watanabe, L, Bleicher, L, Colau, D, Renauld, J.-C, Polikarpov, I. | Deposit date: | 2009-02-14 | Release date: | 2009-04-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.756 Å) | Cite: | Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22 FEBS Lett., 583, 2009
|
|
425D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 425d by Molmil](/molmil-images/mine/425d) | 5'-D(*AP*CP*CP*GP*GP*TP*AP*CP*CP*GP*GP*T)-3' | Descriptor: | DNA (5'-D(*AP*CP*CP*GP*GP*TP*AP*CP*CP*GP*GP*T)-3') | Authors: | Rozenberg, H, Rabinovich, D, Frolow, F, Hegde, R.S, Shakked, Z. | Deposit date: | 1998-09-14 | Release date: | 1999-10-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural code for DNA recognition revealed in crystal structures of papillomavirus E2-DNA targets. Proc.Natl.Acad.Sci.USA, 95, 1998
|
|
3GAD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gad by Molmil](/molmil-images/mine/3gad) | Structure of apomif | Descriptor: | ACETIC ACID, Macrophage migration inhibitory factor-like protein, SULFATE ION | Authors: | Zhou, Y.-F, Su, X.-D, Shao, D, Wang, H. | Deposit date: | 2009-02-17 | Release date: | 2009-12-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and functional comparison of MIF ortholog from Plasmodium yoelii with MIF from its rodent host Mol.Immunol., 47, 2010
|
|
432D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 432d by Molmil](/molmil-images/mine/432d) | D(GGCCAATTGG) COMPLEXED WITH DAPI | Descriptor: | 6-AMIDINE-2-(4-AMIDINO-PHENYL)INDOLE, DNA (5'-D(*GP*GP*CP*CP*AP*AP*TP*TP*GP*G)-3') | Authors: | Vlieghe, D, Van Meervelt, L. | Deposit date: | 1998-10-14 | Release date: | 1999-12-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Crystal structure of d(GGCCAATTGG) complexed with DAPI reveals novel binding mode. Biochemistry, 38, 1999
|
|
3R36
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3r36 by Molmil](/molmil-images/mine/3r36) | Crystal structure of Arthrobacter sp. strain SU 4-hydroxybenzoyl CoA thioesterase mutant E73Q complexed with 4-hydroxybenzoic acid | Descriptor: | 4-hydroxybenzoyl-CoA thioesterase, P-HYDROXYBENZOIC ACID | Authors: | Holden, H.M, Thoden, J.B, Song, F, Zhuang, Z, Trujillo, M, Dunaway-Mariano, D. | Deposit date: | 2011-03-15 | Release date: | 2012-03-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Catalytic Mechanism of the Hotdog-fold Enzyme Superfamily 4-Hydroxybenzoyl-CoA Thioesterase from Arthrobacter sp. Strain SU. Biochemistry, 51, 2012
|
|
8BBW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bbw by Molmil](/molmil-images/mine/8bbw) | Crystal structure of medical leech destabilase (low salt) | Descriptor: | CHLORIDE ION, GLYCEROL, Lysozyme | Authors: | Marin, E, Bukhdruker, S, Manuvera, V, Kornilov, D, Zinovev, E, Bobrovsky, P, Lazarev, V, Borshchevskiy, V. | Deposit date: | 2022-10-14 | Release date: | 2023-02-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis for inhibition of thrombolytic destabilase
from medical leech by physiological sodium concentrations To Be Published
|
|
4A94
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4a94 by Molmil](/molmil-images/mine/4a94) | Structure of the carboxypeptidase inhibitor from Nerita versicolor in complex with human CPA4 | Descriptor: | CARBOXYPEPTIDASE A4, CARBOXYPEPTIDASE INHIBITOR, NITRATE ION, ... | Authors: | Covaleda, G, Alonso, M, Chavez, M.A, Aviles, F.X, Reverter, D. | Deposit date: | 2011-11-23 | Release date: | 2011-12-28 | Last modified: | 2012-03-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of a Novel Metallo-Carboxypeptidase Inhibitor from the Marine Mollusk Nerita Versicolor in Complex with Human Carboxypeptidase A4. J.Biol.Chem., 287, 2012
|
|
5TJA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5tja by Molmil](/molmil-images/mine/5tja) | I-II linker of TRPML1 channel at pH 6 | Descriptor: | Mucolipin-1 | Authors: | Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J. | Deposit date: | 2016-10-04 | Release date: | 2017-01-25 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel. Nat. Struct. Mol. Biol., 24, 2017
|
|
5TJC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5tjc by Molmil](/molmil-images/mine/5tjc) | I-II linker of TRPML1 channel at pH 7.5 | Descriptor: | Mucolipin-1 | Authors: | Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J. | Deposit date: | 2016-10-04 | Release date: | 2017-01-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel. Nat. Struct. Mol. Biol., 24, 2017
|
|