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PDB: 22297 件

4AAQ
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ATP-triggered molecular mechanics of the chaperonin GroEL
分子名称: 60 KDA CHAPERONIN, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Clare, D.K, Vasishtan, D, Stagg, S, Quispe, J, Farr, G.W, Topf, M, Horwich, A.L, Saibil, H.R.
登録日2011-12-05
公開日2012-12-12
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the Groel Chaperonin.
Cell(Cambridge,Mass.), 149, 2012
4A93
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RNA Polymerase II elongation complex containing a CPD Lesion
分子名称: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*T*TTP*TP*TP*CP*C BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP*AP)-3', ...
著者Walmacq, C, Cheung, A.C.M, Kireeva, M.L, Lubkowska, L, Ye, C, Gotte, D, Strathern, J.N, Carell, T, Cramer, P, Kashlev, M.
登録日2011-11-23
公開日2012-03-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
Mol.Cell, 46, 2012
2KG4
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Three-dimensional structure of human Gadd45alpha in solution by NMR
分子名称: Growth arrest and DNA-damage-inducible protein GADD45 alpha
著者Sanchez, R, Pantoja-Uceda, D, Prieto, J, Diercks, T, Campos-Olivas, R, Blanco, F.J.
登録日2009-03-04
公開日2009-03-31
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase
J.Biol.Chem., 285, 2010
3DWC
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Trypanosoma Cruzi Metallocarboxypeptidase 1
分子名称: ALANINE, COBALT (II) ION, GLYCEROL, ...
著者Niemirowicz, G, Fernandez, D, Sola, M, Cazzulo, J.J, Aviles, F.X, Gomis-Ruth, F.X.
登録日2008-07-22
公開日2008-09-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The molecular analysis of Trypanosoma cruzi metallocarboxypeptidase 1 provides insight into fold and substrate specificity
Mol.Microbiol., 70, 2008
4AOJ
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Human TrkA in complex with the inhibitor AZ-23
分子名称: 5-chloranyl-N2-[(1S)-1-(5-fluoranylpyridin-2-yl)ethyl]-N4-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyrimidine-2,4-diamine, HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR, ZINC ION
著者Wang, T, Lamb, M.L, Block, M.H, Davies, A.M, Han, Y, Hoffmann, E, Ioannidis, S, Josey, J.A, Liu, Z, Lyne, P.D, MacIntyre, T, Mohr, P.J, Omer, C.A, Sjogren, T, Thress, K, Wang, B, Wang, H, Yu, D, Zhang, H.
登録日2012-03-28
公開日2012-08-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Discovery of Disubstituted Imidazo[4,5-B]Pyridines and Purines as Potent Trka Inhibitors
Acs Med.Chem.Lett., 3, 2012
5UJG
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ovGRN12-35_3s
分子名称: Granulin
著者Bansal, P, Smout, M, Wilson, D, Caceres, C.C, Dastpeyman, M, Sotillo, J, Seifert, J, Brindley, P, Loukas, A, Daly, N.
登録日2017-01-17
公開日2018-01-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Development of a Potent Wound Healing Agent Based on the Liver Fluke Granulin Structural Fold.
J. Med. Chem., 60, 2017
3SI2
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Structure of glycosylated murine glutaminyl cyclase in presence of the inhibitor PQ50 (PDBD150)
分子名称: 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Parthier, C, Carrillo, D, Stubbs, M.T.
登録日2011-06-17
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of Glycosylated Mammalian Glutaminyl Cyclases Reveal Conformational Variability near the Active Center.
Biochemistry, 50, 2011
5UJN
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Representative 2-conformer ensembles of K27-linked Ub2 from RDC data
分子名称: Ubiquitin
著者Castaneda, C.A, Fushman, D.
登録日2017-01-18
公開日2018-08-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Linkage via K27 Bestows Ubiquitin Chains with Unique Properties among Polyubiquitins.
Structure, 24, 2016
4AR7
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X-ray structure of the cyan fluorescent protein mTurquoise
分子名称: GREEN FLUORESCENT PROTEIN
著者von Stetten, D, Noirclerc-Savoye, M, Goedhart, J, Gadella, T.W.J, Royant, A.
登録日2012-04-21
公開日2012-08-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Structure of a Fluorescent Protein from Aequorea Victoria Bearing the Obligate-Monomer Mutation A206K.
Acta Crystallogr.,Sect.F, 68, 2012
2K71
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Structure and dynamics of a DNA GNRA hairpin solved vy high-sensitivity NMR with two independent converging methods, simulated annealing (DYANA) and mesoscopic molecular modelling (BCE/AMBER)
分子名称: 5'-D(*DGP*DCP*DGP*DAP*DAP*DAP*DGP*DC)-3'
著者Santini, G.P.H, Cognet, J.A.H, Xu, D, Singarapu, K.K, Herve du Penhoat, C.L.M.
登録日2008-07-29
公開日2009-07-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Nucleic acid folding determined by mesoscale modeling and NMR spectroscopy: solution structure of d(GCGAAAGC).
J.Phys.Chem.B, 113, 2009
4A4G
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Solution structure of SMN Tudor domain in complex with asymmetrically dimethylated arginine
分子名称: NG,NG-DIMETHYL-L-ARGININE, SURVIVAL MOTOR NEURON PROTEIN
著者Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M.
登録日2011-10-12
公開日2011-11-30
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins
Nat.Struct.Mol.Biol., 18, 2011
5UP1
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Solution structure of the de novo mini protein EEHEE_rd3_1049
分子名称: EEHEE_rd3_1049
著者Houliston, S, Rocklin, G.J, Lemak, A, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H.
登録日2017-02-01
公開日2017-07-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Global analysis of protein folding using massively parallel design, synthesis, and testing.
Science, 357, 2017
3WXZ
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BU of 3wxz by Molmil
The structure of the I375F mutant of CsyB
分子名称: Putative uncharacterized protein csyB
著者Mori, T, Yang, D, Matsui, T, Morita, H, Fujii, I, Abe, I.
登録日2014-08-13
公開日2015-01-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Structural basis for the formation of acylalkylpyrones from two beta-ketoacyl units by the fungal type III polyketide synthase CsyB.
J.Biol.Chem., 290, 2015
2KBF
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solution structure of carboxyl-terminal domain of Dbp5p
分子名称: ATP-dependent RNA helicase DBP5
著者Fan, J.S, Zhang, J, Yang, D.
登録日2008-11-28
公開日2009-10-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution and crystal structures of mRNA exporter Dbp5p and its interaction with nucleotides.
J.Mol.Biol., 388, 2009
2H3S
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BU of 2h3s by Molmil
cis-Azobenzene-avian pancreatic polypeptide bound to DPC micelles
分子名称: (3-{(Z)-[3-(AMINOMETHYL)PHENYL]DIAZENYL}PHENYL)ACETIC ACID, Pancreatic hormone
著者Jurt, S, Aemissegger, A, Guentert, P, Zerbe, O, Hilvert, D.
登録日2006-05-23
公開日2006-09-12
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献A Photoswitchable Miniprotein Based on the Sequence of Avian Pancreatic Polypeptide
Angew.Chem.Int.Ed.Engl., 45, 2006
2HAF
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Crystal structure of a putative translation repressor from Vibrio cholerae
分子名称: Putative translation repressor
著者Sugadev, R, Seetharaman, J, Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-06-12
公開日2006-07-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Crystal structure of a putative translation repressor from Vibrio cholerae
To be Published
8AY5
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Human rhinovirus 2 empty particle in situ
分子名称: Capsid protein VP1, Capsid protein VP2, VP3
著者Ishemgulova, A, Mukhamedova, L, Trebichalska, Z, Payne, P, Smerdova, L, Moravcova, J, Hrebik, D, Buchta, D, Skubnik, K, Fuzik, T, Novacek, J, Plevka, P.
登録日2022-09-01
公開日2023-09-13
実験手法ELECTRON MICROSCOPY (7.1 Å)
主引用文献Endosome rupture enables enteroviruses to infect cells.
To Be Published
8AY4
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Human rhinovirus 2 virion in situ
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Ishemgulova, A, Mukhamedova, L, Trebichalska, Z, Payne, P, Smerdova, L, Moravcova, J, Hrebik, D, Buchta, D, Skubnik, K, Fuzik, T, Novacek, J, Plevka, P.
登録日2022-09-01
公開日2023-09-13
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Endosome rupture enables enteroviruses to infect cells.
To Be Published
2HAM
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BU of 2ham by Molmil
Crystal structure of VDR LBD complexed to 2alpha-propyl-calcitriol
分子名称: 2ALPHA-PROPYL-1ALPHA,25-DIHYDROXYVITAMIN D3, Vitamin D3 receptor
著者Hourai, S, Rochel, N, Moras, D.
登録日2006-06-13
公開日2006-08-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Probing a Water Channel near the A-Ring of Receptor-Bound 1alpha,25-Dihydroxyvitamin D3 with Selected 2alpha-Substituted Analogues
J.Med.Chem., 49, 2006
5VJO
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Complex between HyHEL10 Fab fragment heavy chain mutant I29F and Pekin duck egg lysozyme isoform I (DEL-I)
分子名称: CHLORIDE ION, HyHEL10 heavy chain Fab fragment carrying I29F mutation., HyHEL10 light chain Fab fragment, ...
著者Langley, D.B, Christ, D.
登録日2017-04-19
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.
Science, 360, 2018
3DKZ
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Crystal structure of the Q7W9W5_BORPA protein from Bordetella parapertussis. Northeast Structural Genomics Consortium target BpR208C.
分子名称: Thioesterase superfamily protein
著者Vorobiev, S.M, Su, M, Seetharaman, J, Wang, D, Ciccosanti, C, Foote, E.L, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2008-06-26
公開日2008-08-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the Q7W9W5_BORPA protein from Bordetella parapertussis.
To be Published
5VKZ
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Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies
分子名称: Mitochondrial distribution and morphology protein 12
著者Egea, P.F, AhYoung, A.P, Lu, B, Tan, H.R, Cascio, D.
登録日2017-04-24
公開日2017-07-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies.
Biochem. Biophys. Res. Commun., 488, 2017
3DRF
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Lactococcal OppA complexed with an endogenous peptide in the closed conformation
分子名称: Oligopeptide-binding protein oppA, endogenous peptide
著者Berntsson, R.P.-A, Doeven, M.K, Duurkens, R.H, Sengupta, D, Marrink, S.-J, Thunnissen, A.-M, Poolman, B, Slotboom, D.-J.
登録日2008-07-11
公開日2009-03-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The structural basis for peptide selection by the transport receptor OppA
Embo J., 28, 2009
2GK3
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Cytoplasmic Protein STM3548 from Salmonella typhimurium
分子名称: GLYCEROL, putative cytoplasmic protein
著者Petrova, T, Cuff, M.E, Wu, R.Y, Holzle, D, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2006-03-31
公開日2006-05-02
最終更新日2011-08-03
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Novel hexamerization motif is discovered in a conserved cytoplasmic protein from Salmonella typhimurium.
J.Struct.Funct.Genom., 8, 2007
3X1I
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hPPARgamma Ligand binding domain in complex with 6-oxo-tetracosahexaenoic acid
分子名称: (8E,12Z,15Z,18Z,21Z)-6-oxotetracosa-8,12,15,18,21-pentaenoic acid, Peroxisome proliferator-activated receptor gamma
著者Egawa, D, Itoh, T, Yamamoto, K.
登録日2014-11-18
公開日2015-04-08
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Characterization of covalent bond formation between PPAR gamma and oxo-fatty acids.
Bioconjug.Chem., 26, 2015

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