3USV
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2HXC
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3FWB
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![BU of 3fwb by Molmil](/molmil-images/mine/3fwb) | Sac3:Sus1:Cdc31 complex | 分子名称: | Cell division control protein 31, Nuclear mRNA export protein SAC3, Protein SUS1 | 著者 | Stewart, M, Jani, D. | 登録日 | 2009-01-17 | 公開日 | 2009-04-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export. Mol.Cell, 33, 2009
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3FWK
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2HZI
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![BU of 2hzi by Molmil](/molmil-images/mine/2hzi) | Abl kinase domain in complex with PD180970 | 分子名称: | 6-(2,6-DICHLOROPHENYL)-2-[(4-FLUORO-3-METHYLPHENYL)AMINO]-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, Proto-oncogene tyrosine-protein kinase ABL1 | 著者 | Cowan-Jacob, S.W, Fendrich, G, Liebetanz, J, Fabbro, D, Manley, P. | 登録日 | 2006-08-09 | 公開日 | 2007-01-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia. ACTA CRYSTALLOGR.,SECT.D, 63, 2007
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3UWV
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![BU of 3uwv by Molmil](/molmil-images/mine/3uwv) | Crystal structure of Staphylococcus Aureus triosephosphate isomerase complexed with 2-phosphoglyceric acid | 分子名称: | 2-PHOSPHOGLYCERIC ACID, SODIUM ION, Triosephosphate isomerase | 著者 | Mukherjee, S, Roychowdhury, A, Dutta, D, Das, A.K. | 登録日 | 2011-12-03 | 公開日 | 2012-10-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Crystal structures of triosephosphate isomerase from methicillin resistant Staphylococcus aureus MRSA252 provide structural insights into novel modes of ligand binding and unique conformations of catalytic loop Biochimie, 94, 2012
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2I0R
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3UC9
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2I5N
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![BU of 2i5n by Molmil](/molmil-images/mine/2i5n) | 1.96 A X-ray structure of photosynthetic reaction center from Rhodopseudomonas viridis:Crystals grown by microfluidic technique | 分子名称: | 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, ... | 著者 | Li, L, Mustafi, D, Fu, Q, Tereshko, V, Chen, D.L, Tice, J.D, Ismagilov, R.F. | 登録日 | 2006-08-25 | 公開日 | 2006-09-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins. Proc.Natl.Acad.Sci.Usa, 103, 2006
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8A8F
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![BU of 8a8f by Molmil](/molmil-images/mine/8a8f) | Crystal structure of Glc7 phosphatase in complex with the regulatory region of Ref2 | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, RNA end formation protein 2, ... | 著者 | Carminati, M, Manav, C.M, Bellini, D, Passmore, L.A. | 登録日 | 2022-06-22 | 公開日 | 2023-11-29 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A direct interaction between CPF and RNA Pol II links RNA 3' end processing to transcription. Mol.Cell, 83, 2023
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5TUB
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![BU of 5tub by Molmil](/molmil-images/mine/5tub) | Crystal Structure of the Shark TBC1D15 GAP Domain | 分子名称: | Shark TBC1D15 GTPase-activating Protein | 著者 | Chen, Y.-N, Wang, W, Cheng, D, Ge, Y, Gu, X, Zhou, X.E, Ye, F, Xu, H.E, Lv, Z. | 登録日 | 2016-11-05 | 公開日 | 2017-02-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal structure of TBC1D15 GTPase-activating protein (GAP) domain and its activity on Rab GTPases. Protein Sci., 26, 2017
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2I3P
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![BU of 2i3p by Molmil](/molmil-images/mine/2i3p) | K28R mutant of Homing Endonuclease I-CreI | 分子名称: | 5'-D(*CP*GP*AP*AP*AP*TP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*AP*TP*TP*TP*GP*C)-3', 5'-D(*GP*CP*AP*AP*AP*TP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*AP*TP*TP*TP*CP*G)-3', CALCIUM ION, ... | 著者 | Sussman, D, Rosen, L. | 登録日 | 2006-08-20 | 公開日 | 2006-09-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Homing endonuclease I-CreI derivatives with novel DNA target specificities. Nucleic Acids Res., 34, 2006
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7ZVF
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![BU of 7zvf by Molmil](/molmil-images/mine/7zvf) | Crystal structure of human cathepsin L in complex with covalently bound CLIK148 | 分子名称: | (2S)-N-[(2S)-1-(dimethylamino)-1-oxidanylidene-3-phenyl-propan-2-yl]-2-oxidanyl-N'-(2-pyridin-2-ylethyl)butanediamide, 1,2-ETHANEDIOL, Cathepsin L, ... | 著者 | Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Tsuge, H, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. | 登録日 | 2022-05-15 | 公開日 | 2023-11-29 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
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2I72
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![BU of 2i72 by Molmil](/molmil-images/mine/2i72) | AmpC beta-lactamase in complex with 5-diformylaminomethyl-benzo[b]thiophen-2-boronic acid | 分子名称: | Beta-lactamase, {5-[(DIFORMYLAMINO)METHYL]-1-BENZOTHIEN-2-YL}BORONIC ACID | 著者 | Venturelli, A, Cancian, L, Tondi, D, Morandi, F, Cannazza, G, Segatore, B, Prati, F, Amicosante, G, Shoichet, B.K, Costi, M.P. | 登録日 | 2006-08-30 | 公開日 | 2007-09-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Optimizing Cell Permeation of an Antibiotic Resistance Inhibitor for Improved Efficacy J.Med.Chem., 50, 2007
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3UE7
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![BU of 3ue7 by Molmil](/molmil-images/mine/3ue7) | X-ray crystal structure of a novel topological analogue of crambin | 分子名称: | Crambin, D-Crambin | 著者 | Mandal, K, Pentelute, B.L, Bang, D, Gates, Z.P, Torbeev, V.Y, Kent, S.B.H. | 登録日 | 2011-10-28 | 公開日 | 2012-02-08 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | Design, total chemical synthesis, and x-ray structure of a protein having a novel linear-loop polypeptide chain topology. Angew.Chem.Int.Ed.Engl., 51, 2012
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5U9G
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![BU of 5u9g by Molmil](/molmil-images/mine/5u9g) | 3.2 A cryo-EM ArfA-RF2 ribosome rescue complex (Structure I) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Demo, G, Svidritskiy, E, Madireddy, R, Diaz-Avalos, R, Grant, T, Grigorieff, N, Sousa, D, Korostelev, A.A. | 登録日 | 2016-12-16 | 公開日 | 2017-03-22 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mechanism of ribosome rescue by ArfA and RF2. Elife, 6, 2017
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3URJ
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![BU of 3urj by Molmil](/molmil-images/mine/3urj) | Type IV native endothiapepsin | 分子名称: | Endothiapepsin, SULFATE ION | 著者 | Bailey, D, Cooper, J.B. | 登録日 | 2011-11-22 | 公開日 | 2012-04-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases. Acta Crystallogr.,Sect.D, 68, 2012
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8B0H
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![BU of 8b0h by Molmil](/molmil-images/mine/8b0h) | 2C9, C5b9-CD59 cryoEM structure | 分子名称: | CD59 glycoprotein, Complement C5, Complement component C6, ... | 著者 | Couves, E.C, Gardner, S, Bubeck, D. | 登録日 | 2022-09-07 | 公開日 | 2023-02-22 | 最終更新日 | 2023-03-01 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for membrane attack complex inhibition by CD59. Nat Commun, 14, 2023
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2IB0
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![BU of 2ib0 by Molmil](/molmil-images/mine/2ib0) | Crystal structure of a conserved hypothetical protein, rv2844, from Mycobacterium tuberculosis | 分子名称: | CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN | 著者 | Yu, M, Bursey, E.H, Radhakannan, T, Kim, C.Y, Kaviratne, T, Woodruff, T, Segelke, B.W, Lekin, T, Toppani, D, Terwilliger, T.C, Hung, L.W, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI) | 登録日 | 2006-09-08 | 公開日 | 2006-09-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a conserved hypothetical protein, rv2844, from Mycobacterium tuberculosis To be Published
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8AMZ
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![BU of 8amz by Molmil](/molmil-images/mine/8amz) | Spinach 19S proteasome | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1 homolog, 26S proteasome non-ATPase regulatory subunit 2 homolog, 26S proteasome regulatory subunit 7, ... | 著者 | Kandolf, S, Grishkovskaya, I, Meinhart, A, Haselbach, D. | 登録日 | 2022-08-04 | 公開日 | 2022-08-24 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structure of the plant 26S proteasome Plant Communications, 3, 2022
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5TPQ
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![BU of 5tpq by Molmil](/molmil-images/mine/5tpq) | E. coli alkaline phosphatase D101A, D153A, R166S, E322A, K328A mutant | 分子名称: | Alkaline phosphatase, PHOSPHATE ION, ZINC ION | 著者 | Sunden, F, AlSadhan, I, Lyubimov, A.Y, Doukov, T, Swan, J, Herschlag, D. | 登録日 | 2016-10-20 | 公開日 | 2017-11-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Differential catalytic promiscuity of the alkaline phosphatase superfamily bimetallo core reveals mechanistic features underlying enzyme evolution. J. Biol. Chem., 292, 2017
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3UE6
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2GA6
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![BU of 2ga6 by Molmil](/molmil-images/mine/2ga6) | The crystal structure of SARS nsp10 without zinc ion as additive | 分子名称: | ZINC ION, orf1a polyprotein | 著者 | Su, D, Lou, Z, Sun, F, Zhai, Y, Yang, H, Rao, Z. | 登録日 | 2006-03-08 | 公開日 | 2006-08-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Dodecamer Structure of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein nsp10 J.Virol., 80, 2006
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3GA2
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![BU of 3ga2 by Molmil](/molmil-images/mine/3ga2) | Crystal structure of the Endonuclease_V (BSU36170) from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR624 | 分子名称: | Endonuclease V | 著者 | Forouhar, F, Abashidze, M, Hussain, M, Seetharaman, J, Janjua, H, Fang, Y, Xiao, R, Cunningham, K, Ma, L.-C, Owens, L, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-02-16 | 公開日 | 2009-02-24 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of the Endonuclease_V (BSU36170) from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR624 To be Published
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5TPH
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![BU of 5tph by Molmil](/molmil-images/mine/5tph) | Crystal structure of a de novo designed protein homodimer with curved beta-sheet | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, de novo NTF2 homodimer | 著者 | Basanta, B, Marcos, E, Oberdorfer, G, Chidyausiku, T.M, Sankaran, B, Baker, D. | 登録日 | 2016-10-20 | 公開日 | 2017-01-25 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Principles for designing proteins with cavities formed by curved beta sheets. Science, 355, 2017
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