6E12
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e12 by Molmil](/molmil-images/mine/6e12) | Crystal Structure of the Alr8543 protein in complex with Oleic Acid and magnesium ion from Nostoc sp. PCC 7120, Northeast Structural Genomics Consortium Target NsR141 | 分子名称: | Alr8543 protein, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Forouhar, F, Neely, H, Seetharaman, J, Xiao, R, Ciccosanti, C, Patel, D, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2018-07-09 | 公開日 | 2018-07-25 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure of the Alr8543 protein in complex with Oleic Acid and magnesium ion from Nostoc sp. PCC 7120, Northeast Structural Genomics Consortium Target NsR141 To Be Published
|
|
6TGI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tgi by Molmil](/molmil-images/mine/6tgi) | Crystal structure of VIM-2 in complex with triazole-based inhibitor OP24 | 分子名称: | 5-(4-chloranyl-1,5-dimethyl-pyrazol-3-yl)-4-ethyl-1,2,4-triazole-3-thiol, FORMIC ACID, Vim-1, ... | 著者 | Maso, L, Spirakis, F, Santucci, M, Simon, C, Docquier, J.D, Cruciani, G, Costi, M.P, Tondi, D, Cendron, L. | 登録日 | 2019-11-15 | 公開日 | 2020-10-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Virtual screening identifies broad-spectrum beta-lactamase inhibitors with activity on clinically relevant serine- and metallo-carbapenemases. Sci Rep, 10, 2020
|
|
6TAY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tay by Molmil](/molmil-images/mine/6tay) | Mouse RNF213 mutant R4753K modeling the Moyamoya-disease-related Human variant R4810K | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNF213,E3 ubiquitin-protein ligase RNF213,E3 ubiquitin-protein ligase RNF213, ... | 著者 | Ahel, J, Meinhart, A, Haselbach, D, Clausen, T. | 登録日 | 2019-10-31 | 公開日 | 2020-07-01 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism. Elife, 9, 2020
|
|
6TKG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tkg by Molmil](/molmil-images/mine/6tkg) | Tsetse thrombin inhibitor in complex with human alpha-thrombin - orthorhombic form at 12keV | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Prothrombin, ... | 著者 | Calisto, B.M, Ripoll-Rozada, J, de Sanctis, D, Pereira, P.J.B. | 登録日 | 2019-11-28 | 公開日 | 2020-11-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Sulfotyrosine-Mediated Recognition of Human Thrombin by a Tsetse Fly Anticoagulant Mimics Physiological Substrates. Cell Chem Biol, 28, 2021
|
|
6TC2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tc2 by Molmil](/molmil-images/mine/6tc2) | Monoclinic human insulin in complex with p-coumaric acid | 分子名称: | 4'-HYDROXYCINNAMIC ACID, Insulin, PHOSPHATE ION, ... | 著者 | Triandafillidis, D.-P, Parthenios, N, Spiliopoulou, M, Valmas, A, Kosinas, C, Gozzo, F, Reinle-Schmitt, M, Beckers, D, Degen, T, Pop, M, Fitch, A, Wollenhaupt, J, Weiss, M.S, Karavassili, F, Margiolaki, I. | 登録日 | 2019-11-04 | 公開日 | 2020-11-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Insulin polymorphism induced by two polyphenols: new crystal forms and advances in macromolecular powder diffraction. Acta Crystallogr D Struct Biol, 76, 2020
|
|
6TD7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6td7 by Molmil](/molmil-images/mine/6td7) | Structure of truncated hemoglobin THB11 from Chlamydomonas reinhardtii | 分子名称: | CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE, THB11 | 著者 | Huwald, D, Gasper, R, Hemschemeier, A, Hofmann, E. | 登録日 | 2019-11-08 | 公開日 | 2020-02-26 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Distinctive structural properties of THB11, a pentacoordinate Chlamydomonas reinhardtii truncated hemoglobin with N- and C-terminal extensions. J.Biol.Inorg.Chem., 25, 2020
|
|
6S09
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s09 by Molmil](/molmil-images/mine/6s09) | C-terminally extended and N-terminally truncated variant of FimA E. coli at 1.5 Angstrom resolution | 分子名称: | ACETIC ACID, FimA, SODIUM ION, ... | 著者 | Zyla, D, Echeverria, B, Glockshuber, R. | 登録日 | 2019-06-14 | 公開日 | 2020-07-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.502 Å) | 主引用文献 | Donor strand sequence, rather than donor strand orientation, determines the stability and non-equilibrium folding of the type 1 pilus subunit FimA. J.Biol.Chem., 295, 2020
|
|
6E5C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e5c by Molmil](/molmil-images/mine/6e5c) | Solution NMR structure of a de novo designed double-stranded beta-helix | 分子名称: | De novo beta protein | 著者 | Marcos, E, Chidyausiku, T.M, McShan, A, Evangelidis, T, Nerli, S, Sgourakis, N, Tripsianes, K, Baker, D. | 登録日 | 2018-07-19 | 公開日 | 2018-11-07 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | De novo design of a non-local beta-sheet protein with high stability and accuracy. Nat. Struct. Mol. Biol., 25, 2018
|
|
3HOW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3how by Molmil](/molmil-images/mine/3how) | Complete RNA polymerase II elongation complex III with a T-U mismatch and a frayed RNA 3'-uridine | 分子名称: | 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3', ... | 著者 | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | 登録日 | 2009-06-03 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
|
|
6E88
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e88 by Molmil](/molmil-images/mine/6e88) | Cryo-EM structure of C. elegans GDP-microtubule | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Tubulin alpha-2 chain, ... | 著者 | Chaaban, S, Jariwala, S, Chieh-Ting, H, Redemann, S, Kollman, J, Muller-Reichert, T, Sept, D, Bui, K.H, Brouhard, G.J. | 登録日 | 2018-07-27 | 公開日 | 2018-10-10 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | The Structure and Dynamics of C. elegans Tubulin Reveals the Mechanistic Basis of Microtubule Growth. Dev. Cell, 47, 2018
|
|
6E9R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e9r by Molmil](/molmil-images/mine/6e9r) | DHF46 filament | 分子名称: | DHF46 filament | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | 登録日 | 2018-08-01 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | 主引用文献 | De novo design of self-assembling helical protein filaments. Science, 362, 2018
|
|
6GDH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gdh by Molmil](/molmil-images/mine/6gdh) | Holliday Junctions formed from Telomeric DNA | 分子名称: | DNA (5'-D(*CP*TP*AP*AP*CP*CP*CP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3') | 著者 | Parkinson, G.N, Haider, S, Li, P, Khiali, S, Munnur, D, Ramanathan, A. | 登録日 | 2018-04-23 | 公開日 | 2018-11-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Holliday Junctions Formed from Human Telomeric DNA. J. Am. Chem. Soc., 140, 2018
|
|
6RV3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rv3 by Molmil](/molmil-images/mine/6rv3) | Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation with a bound inhibitor BAY 1000493 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DECYL-BETA-D-MALTOPYRANOSIDE, ... | 著者 | Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2019-05-30 | 公開日 | 2019-08-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature, 582, 2020
|
|
6GDN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gdn by Molmil](/molmil-images/mine/6gdn) | Holliday Junctions formed from Telomeric DNA | 分子名称: | MAGNESIUM ION, Telomere DNA (42-MER) | 著者 | Parkinson, G.N, Haider, S, Li, P, Khiali, S, Munnur, D, Ramanathan, A. | 登録日 | 2018-04-24 | 公開日 | 2018-11-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Holliday Junctions Formed from Human Telomeric DNA. J. Am. Chem. Soc., 140, 2018
|
|
3HY6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hy6 by Molmil](/molmil-images/mine/3hy6) | Structure of human MTHFS with ADP | 分子名称: | 5-formyltetrahydrofolate cyclo-ligase, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Wu, D, Li, Y, Song, G, Cheng, C, Shaw, N, Liu, Z.-J. | 登録日 | 2009-06-22 | 公開日 | 2009-07-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues Cancer Res., 69, 2009
|
|
6G5K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g5k by Molmil](/molmil-images/mine/6g5k) | Crystal structure of the binding domain of Botulinum Neurotoxin type B in complex with human synaptotagmin 1 | 分子名称: | Botulinum neurotoxin type B, Synaptotagmin-1 | 著者 | Masuyer, G, Elliot, M, Favre-Guilmard, C, Liu, S.M, Maignel, J, Beard, M, Carre, D, Kalinichev, M, Lezmi, S, Mir, I, Nicoleau, C, Palan, S, Perier, C, Raban, E, Dong, M, Krupp, J, Stenmark, P. | 登録日 | 2018-03-29 | 公開日 | 2019-01-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models. Sci Adv, 5, 2019
|
|
6S35
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s35 by Molmil](/molmil-images/mine/6s35) | |
6GFN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gfn by Molmil](/molmil-images/mine/6gfn) | METTL16 MTase domain | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase | 著者 | Chen, K.M, Mendel, M, Homolka, D, McCarthy, A.A, Pillai, R.S. | 登録日 | 2018-05-01 | 公開日 | 2018-09-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development. Mol. Cell, 71, 2018
|
|
6S46
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s46 by Molmil](/molmil-images/mine/6s46) | Room temperature structure of the LOV2 domain of phototropin-2 from Arabidopsis thaliana 4158 ms after initiation of illumination, determined with a serial crystallography approach | 分子名称: | FLAVIN MONONUCLEOTIDE, Phototropin-2 | 著者 | Aumonier, S, Santoni, G, Gotthard, G, von Stetten, D, Leonard, G, Royant, A. | 登録日 | 2019-06-26 | 公開日 | 2020-07-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Millisecond time-resolved serial oscillation crystallography of a blue-light photoreceptor at a synchrotron. Iucrj, 7, 2020
|
|
6R3F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r3f by Molmil](/molmil-images/mine/6r3f) | |
6GND
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gnd by Molmil](/molmil-images/mine/6gnd) | Crystal structure of the complex of a Ferredoxin-Flavin Thioredoxin Reductase and a Thioredoxin from Clostridium acetobutylicum at 2.9 A resolution | 分子名称: | 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin, ... | 著者 | Buey, R.M, Fernandez-Justel, D, Balsera, M. | 登録日 | 2018-05-30 | 公開日 | 2018-12-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.889 Å) | 主引用文献 | Ferredoxin-linked flavoenzyme defines a family of pyridine nucleotide-independent thioredoxin reductases. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6RAF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6raf by Molmil](/molmil-images/mine/6raf) | Heterodimeric ABC exporter TmrAB in inward-facing narrow conformation under turnover conditions | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Anti-vesicular stomatitis virus N VHH, ... | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | 登録日 | 2019-04-06 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
|
|
6GP2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gp2 by Molmil](/molmil-images/mine/6gp2) | Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, DOPA-active form | 分子名称: | CALCIUM ION, Ribonucleoside-diphosphate reductase beta chain | 著者 | Srinivas, V, Lebrette, H, Lundin, D, Kutin, Y, Sahlin, M, Lerche, M, Enrich, J, Branca, R.M.M, Cox, N, Sjoberg, B.M, Hogbom, M. | 登録日 | 2018-06-05 | 公開日 | 2018-08-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens. Nature, 563, 2018
|
|
6RAL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ral by Molmil](/molmil-images/mine/6ral) | Heterodimeric ABC exporter TmrAB under turnover conditions in asymmetric unlocked return conformation | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | 登録日 | 2019-04-06 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
|
|
6R43
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r43 by Molmil](/molmil-images/mine/6r43) | |