6TAY

Mouse RNF213 mutant R4753K modeling the Moyamoya-disease-related Human variant R4810K

Summary for 6TAY

Entry DOI	10.2210/pdb6tay/pdb
Related	6TAX
EMDB information	10430
Descriptor	RNF213,E3 ubiquitin-protein ligase RNF213,E3 ubiquitin-protein ligase RNF213, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	rnf213, e3 ligase, aaa-protein, signaling protein
Biological source	Mus musculus (House mouse) More
Total number of polymer chains	1
Total formula weight	528312.62
Authors	Ahel, J.,Meinhart, A.,Haselbach, D.,Clausen, T. (deposition date: 2019-10-31, release date: 2020-07-01, Last modification date: 2021-01-13)
Primary citation	Ahel, J.,Lehner, A.,Vogel, A.,Schleiffer, A.,Meinhart, A.,Haselbach, D.,Clausen, T. Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism. Elife, 9:-, 2020 Cited by PubMed: 32573437 DOI: 10.7554/eLife.56185 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation