6TAY
Mouse RNF213 mutant R4753K modeling the Moyamoya-disease-related Human variant R4810K
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue ATP A 5201 |
| Chain | Residue |
| A | ALA1956 |
| A | ASP2116 |
| A | GLU2119 |
| A | TRP2173 |
| A | ARG2177 |
| A | LYS2460 |
| A | SER2535 |
| A | MG5202 |
| A | GLY1957 |
| A | VAL1958 |
| A | GLY1959 |
| A | LYS1960 |
| A | SER1961 |
| A | LEU1962 |
| A | GLU2060 |
| A | ALA2114 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 5202 |
| Chain | Residue |
| A | SER1961 |
| A | GLU2060 |
| A | ATP5201 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 5203 |
| Chain | Residue |
| A | CYS3962 |
| A | HIS3964 |
| A | CYS3982 |
| A | CYS3985 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 5204 |
| Chain | Residue |
| A | CYS3947 |
| A | CYS3950 |
| A | CYS3967 |
| A | CYS3970 |
Functional Information from PROSITE/UniProt
| site_id | PS00518 |
| Number of Residues | 10 |
| Details | ZF_RING_1 Zinc finger RING-type signature. CdHvYClrCI |
| Chain | Residue | Details |
| A | CYS3962-ILE3971 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 39 |
| Details | Zinc finger: {"description":"RING-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00175","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 72 |
| Details | Zinc finger: {"description":"RZ-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01325","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 30 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile; for E3 ubiquitin-lipopolysaccharide ligase activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU01325","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32573437","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TAX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6TAY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32573437","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TAY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32573437","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TAX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01325","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q63HN8","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"UniProtKB","id":"Q63HN8","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
