6TAY

Mouse RNF213 mutant R4753K modeling the Moyamoya-disease-related Human variant R4810K

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RNF213,E3 ubiquitin-protein ligase RNF213,E3 ubiquitin-protein ligase RNF213	polymer	4638	527650.3	1	UniProt (E9Q555) Pfam (PF00097) Pfam (PF20173)	Mus musculus (House mouse)	Mysterin,RING finger protein 213,RING-type E3 ubiquitin transferase RNF213
2	B (A)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)
3	C (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	D, E (A)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A: 475 - 541 (PDB: 6TAY)
A: 591 - 5148 (UniProt: E9Q555)

PDB	External Database	Details
-	Val 4264	deletion
-	Arg 4265	deletion
-	Asn 4266	deletion
-	Arg 4267	deletion
Lys 4753	Arg 4757	engineered mutation
Gly 5149	-	expression tag
Gly 5150	-	expression tag
Gly 5151	-	expression tag
His 5152	-	expression tag
His 5153	-	expression tag
His 5154	-	expression tag
His 5155	-	expression tag
His 5156	-	expression tag
His 5157	-	expression tag
His 5158	-	expression tag
His 5159	-	expression tag
His 5160	-	expression tag
His 5161	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	527650.3
Non-Polymers*	Number of molecules	4
	Total formula weight	662.3
All*	Total formula weight	528312.6

*Water molecules are not included.