6TDF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tdf by Molmil](/molmil-images/mine/6tdf) | Crystal structure of Aspergillus fumigatus Glucosamine-6-phosphate N-acetyltransferase 1 in complex with compound 3 | 分子名称: | 2-[[3,5-bis(chloranyl)-4-(4~{H}-1,2,4-triazol-3-yl)phenyl]-(2-hydroxyethyl)amino]ethanol, 6-O-phosphono-alpha-D-glucopyranose, ACETYL COENZYME *A, ... | 著者 | Raimi, O.G, Stanley, M, Lockhart, D. | 登録日 | 2019-11-08 | 公開日 | 2020-04-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Targeting a critical step in fungal hexosamine biosynthesis. J.Biol.Chem., 295, 2020
|
|
1XWQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xwq by Molmil](/molmil-images/mine/1xwq) | Structure Of A Cold-Adapted Family 8 Xylanase | 分子名称: | beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, endo-1,4-beta-xylanase | 著者 | De Vos, D, Collins, T, Hoyoux, A, Savvides, S.N, Gerday, C, Van Beeumen, J.J, Feller, G. | 登録日 | 2004-11-02 | 公開日 | 2005-10-11 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Study of the active site residues of a glycoside hydrolase family 8 xylanase J.Mol.Biol., 354, 2005
|
|
3WDO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wdo by Molmil](/molmil-images/mine/3wdo) | Structure of E. coli YajR transporter | 分子名称: | MFS Transporter | 著者 | Jiang, D. | 登録日 | 2013-06-19 | 公開日 | 2013-08-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
1XON
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xon by Molmil](/molmil-images/mine/1xon) | Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Piclamilast | 分子名称: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-(CYCLOPENTYLOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-METHOXYBENZAMIDE, ... | 著者 | Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. | 登録日 | 2004-10-06 | 公開日 | 2004-12-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases. STRUCTURE, 12, 2004
|
|
5V94
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5v94 by Molmil](/molmil-images/mine/5v94) | Pekin duck egg lysozyme isoform III (DEL-III), cubic form | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, ... | 著者 | Langley, D.B, Christ, D. | 登録日 | 2017-03-22 | 公開日 | 2017-11-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural basis of antigen recognition: crystal structure of duck egg lysozyme. Acta Crystallogr D Struct Biol, 73, 2017
|
|
3SP4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sp4 by Molmil](/molmil-images/mine/3sp4) | Crystal structure of aprataxin ortholog Hnt3 from Schizosaccharomyces pombe | 分子名称: | Aprataxin-like protein, SULFATE ION, ZINC ION | 著者 | Gong, Y, Zhu, D, Ding, J, Dou, C, Ren, X, Jiang, T, Wang, D. | 登録日 | 2011-07-01 | 公開日 | 2011-10-12 | 最終更新日 | 2013-07-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA Nat.Struct.Mol.Biol., 18, 2011
|
|
1XSE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xse by Molmil](/molmil-images/mine/1xse) | Crystal Structure of Guinea Pig 11beta-Hydroxysteroid Dehydrogenase Type 1 | 分子名称: | 11beta-hydroxysteroid dehydrogenase type 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Ogg, D, Elleby, B, Norstrom, C, Stefansson, K, Abrahmsen, L, Oppermann, U, Svensson, S. | 登録日 | 2004-10-19 | 公開日 | 2004-11-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The crystal structure of guinea pig 11beta-hydroxysteroid dehydrogenase type 1 provides a model for enzyme-lipid bilayer interactions J.Biol.Chem., 280, 2005
|
|
6TGU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tgu by Molmil](/molmil-images/mine/6tgu) | Crystal structure of human protein kinase CK2alpha'(CSNK2A2 gene product) in complex with the 2-aminothiazole-type inhibitor Cl-OH-3 | 分子名称: | 1,2-ETHANEDIOL, 4-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]amino]-2-oxidanyl-benzoic acid, Casein kinase II subunit alpha' | 著者 | Niefind, K, Lindenblatt, D, Jose, J, Applegate, V.M, Nickelsen, A. | 登録日 | 2019-11-18 | 公開日 | 2020-07-08 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (0.833 Å) | 主引用文献 | Structural and Mechanistic Basis of the Inhibitory Potency of Selected 2-Aminothiazole Compounds on Protein Kinase CK2. J.Med.Chem., 63, 2020
|
|
6TBE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tbe by Molmil](/molmil-images/mine/6tbe) | LC3A in complex with (3R,4S,5R,6R)-5-hydroxy-6-((4-hydroxy-3-(4-hydroxy-3-isopentylbenzamido)-8-methyl-2-oxo-2H-chromen-7-yl)oxy)-3-methoxy-2,2-dimethyltetrahydro-2H-pyran-4-yl carbamate | 分子名称: | 1,2-ETHANEDIOL, Microtubule-associated proteins 1A/1B light chain 3A, NOVOBIOCIN | 著者 | Kramer, J.S, Pogoryelov, D, Hartmann, M, Chaikuad, A, Proschak, E. | 登録日 | 2019-11-01 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.67008042 Å) | 主引用文献 | Demonstrating Ligandability of the LC3A and LC3B Adapter Interface. J.Med.Chem., 64, 2021
|
|
1XT4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xt4 by Molmil](/molmil-images/mine/1xt4) | Urate Oxidase From Aspergillus Flavus Complexed With Guanine | 分子名称: | GUANINE, Uricase | 著者 | Retailleau, P, Colloc'h, N, Vivares, D, Bonnete, F, Castro, B, El Hajji, M, Prange, T. | 登録日 | 2004-10-21 | 公開日 | 2005-03-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Urate oxidase from Aspergillus flavus: new crystal-packing contacts in relation to the content of the active site. Acta Crystallogr.,Sect.D, 61, 2005
|
|
1YMG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ymg by Molmil](/molmil-images/mine/1ymg) | The Channel Architecture of Aquaporin O at 2.2 Angstrom Resolution | 分子名称: | Lens fiber major intrinsic protein, nonyl beta-D-glucopyranoside | 著者 | Harries, W.E.C, Akhavan, D, Miercke, L.J.W, Khademi, S, Stroud, R.M. | 登録日 | 2005-01-20 | 公開日 | 2005-02-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | The Channel Architecture of Aquaporin 0 at a 2.2-A Resolution Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1YNR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ynr by Molmil](/molmil-images/mine/1ynr) | Crystal structure of the cytochrome c-552 from Hydrogenobacter thermophilus at 2.0 resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cytochrome c-552, HEME C, ... | 著者 | Travaglini-Allocatelli, C, Gianni, S, Dubey, V.K, Borgia, A, Di Matteo, A, Bonivento, D, Cutruzzola, F, Bren, K.L, Brunori, M. | 登録日 | 2005-01-25 | 公開日 | 2005-05-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | An Obligatory Intermediate in the Folding Pathway of Cytochrome c552 from Hydrogenobacter thermophilus J.Biol.Chem., 280, 2005
|
|
1YL8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yl8 by Molmil](/molmil-images/mine/1yl8) | 3D Solution Structure of [Tyr3]Octreotate derivatives in DMSO | 分子名称: | [Tyr3]Octreotate peptide | 著者 | Spyroulias, G.A, Galanis, A.S, Petrou, C, Vahliotis, D, Sotiriou, P, Nikolopoulou, A, Nock, B, Maina, T, Cordopatis, P. | 登録日 | 2005-01-19 | 公開日 | 2005-09-20 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | 3D solution structure of [Tyr3]octreotate derivatives in DMSO: structure differentiation of peptide core due to chelate group attachment and biologically active conformation. Med.Chem., 1, 2005
|
|
6TDG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tdg by Molmil](/molmil-images/mine/6tdg) | Crystal structure of Aspergillus fumigatus Glucosamine-6-phosphate N-acetyltransferase 1 in complex with compound 2 | 分子名称: | 2-chloranyl-3-(4~{H}-1,2,4-triazol-3-yl)aniline, ACETYL COENZYME *A, Glucosamine 6-phosphate N-acetyltransferase | 著者 | Raimi, O.G, Stanley, M, Lockhart, D. | 登録日 | 2019-11-08 | 公開日 | 2020-04-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Targeting a critical step in fungal hexosamine biosynthesis. J.Biol.Chem., 295, 2020
|
|
1YL9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yl9 by Molmil](/molmil-images/mine/1yl9) | 3D Solution Structure of [Tyr3]Octreotate derivatives in DMSO | 分子名称: | 3-[(2-AMINOETHYL)AMINO]-2-{[(2-AMINOETHYL)AMINO]METHYL}PROPANAL, [Tyr3]Octreotate | 著者 | Spyroulias, G.A, Galanis, A.S, Petrou, C, Vahliotis, D, Sotiriou, P, Nikolopoulou, A, Nock, B, Maina, T, Cordopatis, P. | 登録日 | 2005-01-19 | 公開日 | 2005-09-20 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | 3D solution structure of [Tyr3]octreotate derivatives in DMSO: structure differentiation of peptide core due to chelate group attachment and biologically active conformation. Med.Chem., 1, 2005
|
|
1YM5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ym5 by Molmil](/molmil-images/mine/1ym5) | Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily. | 分子名称: | Hypothetical 32.6 kDa protein in DAP2-SLT2 intergenic region | 著者 | Liger, D, Quevillon-Cheruel, S, Sorel, I, Bremang, M, Blondeau, K, Aboulfath, I, Janin, J, Van Tilbeurgh, H, Leulliot, N, Paris-Sud Yeast Structural Genomics (YSG) | 登録日 | 2005-01-20 | 公開日 | 2005-08-02 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily Proteins, 60, 2005
|
|
1YMT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ymt by Molmil](/molmil-images/mine/1ymt) | Mouse SF-1 LBD | 分子名称: | 1-CIS-9-OCTADECANOYL-2-CIS-9-HEXADECANOYL PHOSPHATIDYL GLYCEROL, Nuclear receptor 0B2, Steroidogenic factor 1 | 著者 | Krylova, I.N, Sablin, E.P, Moore, J, Xu, R.X, Waitt, G.M, Juzumiene, D, Bynum, J.M, Fletterick, R.J, Willson, T.M, Ingraham, H.A. | 登録日 | 2005-01-21 | 公開日 | 2005-03-15 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1 Cell(Cambridge,Mass.), 120, 2005
|
|
7CRO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cro by Molmil](/molmil-images/mine/7cro) | NSD2 bearing E1099K/T1150A dual mutation in complex with 187-bp NCP | 分子名称: | DNA (168-MER), Histone H2A, Histone H2B, ... | 著者 | Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. | 登録日 | 2020-08-14 | 公開日 | 2020-10-21 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | 主引用文献 | Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases. Nature, 590, 2021
|
|
1YU5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yu5 by Molmil](/molmil-images/mine/1yu5) | Crystal Structure of the Headpiece Domain of Chicken Villin | 分子名称: | Villin | 著者 | Meng, J, Vardar, D, Wang, Y, Guo, H.C, Head, J.F, McKnight, C.J. | 登録日 | 2005-02-11 | 公開日 | 2005-09-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | High-resolution crystal structures of villin headpiece and mutants with reduced f-actin binding activity. Biochemistry, 44, 2005
|
|
1YO1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yo1 by Molmil](/molmil-images/mine/1yo1) | Proton Transfer from His200 in Human Carbonic Anhydrase II | 分子名称: | Carbonic anhydrase II, SULFATE ION, ZINC ION | 著者 | Bhatt, D, Tu, C, Fisher, S.Z, Hernandez Prada, J.A, McKenna, R, Silverman, D.N. | 登録日 | 2005-01-26 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Proton transfer in a Thr200His mutant of human carbonic anhydrase II Proteins, 61, 2005
|
|
1YNQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ynq by Molmil](/molmil-images/mine/1ynq) | aldo-keto reductase AKR11C1 from Bacillus halodurans (holo form) | 分子名称: | GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SODIUM ION, ... | 著者 | Marquardt, T, Kostrewa, D, Winkler, F.K, Li, X.D. | 登録日 | 2005-01-25 | 公開日 | 2005-12-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | High-resolution Crystal Structure of AKR11C1 from Bacillus halodurans: An NADPH-dependent 4-Hydroxy-2,3-trans-nonenal Reductase J.Mol.Biol., 354, 2005
|
|
1YOW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yow by Molmil](/molmil-images/mine/1yow) | human Steroidogenic Factor 1 LBD with bound Co-factor Peptide | 分子名称: | PHOSPHATIDYL ETHANOL, Steroidogenic factor 1, TIF2 peptide | 著者 | Krylova, I.N, Sablin, E.P, Xu, R.X, Waitt, G.M, Juzumiene, D, Williams, J.D, Ingraham, H.A, Willson, T.M, Williams, S.P, Montana, V, Madauss, K.P, Moore, J, Bynum, J.M, Lebedeva, L, MacKay, J.A, Suzawa, M, Guy, R.K, Thornton, J.W. | 登録日 | 2005-01-28 | 公開日 | 2005-05-10 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1 Cell(Cambridge,Mass.), 120, 2005
|
|
7CRR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7crr by Molmil](/molmil-images/mine/7crr) | Native NSD3 bound to 187-bp nucleosome | 分子名称: | DNA (168-MER), DNA(168-MER), Histone H2A, ... | 著者 | Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. | 登録日 | 2020-08-14 | 公開日 | 2020-10-21 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases. Nature, 590, 2021
|
|
1YQJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yqj by Molmil](/molmil-images/mine/1yqj) | Crystal Structure of p38 Alpha in Complex with a Selective Pyridazine Inhibitor | 分子名称: | 6((S)-3-BENZYLPIPERAZIN-1-YL)-3-(NAPHTHALEN-2-YL)-4-(PYRIDIN-4-YL)PYRAZINE, Mitogen-activated protein kinase 14, SULFATE ION | 著者 | Tamayo, N, Liao, H, Goldberg, M, Syed, R, Li, V, Powers, D, Tudor, Y, Yu, V, Wong, M.L, Henkle, B, Middelton, S, Harvey, T, Jang, G, Hungate, R, Dominguez, C. | 登録日 | 2005-02-01 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Design and synthesis of potent pyridazine inhibitors of p38 MAP kinase. Bioorg.Med.Chem.Lett., 15, 2005
|
|
6TEW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tew by Molmil](/molmil-images/mine/6tew) | Crystal structure of human protein kinase CK2alpha' (CSNK2A2 gene product) in complex with the 2-aminothiazole-type inhibitor 27 | 分子名称: | 1,2-ETHANEDIOL, 4-[(4-naphthalen-2-yl-1,3-thiazol-2-yl)amino]-2-oxidanyl-benzoic acid, Casein kinase II subunit alpha' | 著者 | Niefind, K, Lindenblatt, D, Jose, J, Applegate, V.M, Nickelsen, A. | 登録日 | 2019-11-12 | 公開日 | 2020-07-08 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.082 Å) | 主引用文献 | Structural and Mechanistic Basis of the Inhibitory Potency of Selected 2-Aminothiazole Compounds on Protein Kinase CK2. J.Med.Chem., 63, 2020
|
|