2C1J
 
 | | Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3 | | 分子名称: | 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE | | 著者 | Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C. | | 登録日 | 2005-09-15 | | 公開日 | 2005-11-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3.
Mol.Cell, 20, 2005
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6MBN
 | | LptB E163Q in complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Lipopolysaccharide export system ATP-binding protein LptB, ... | | 著者 | Owens, T.W, Ruiz, N, Kahne, D. | | 登録日 | 2018-08-30 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.957 Å) | | 主引用文献 | Combining Mutations That Inhibit Two Distinct Steps of the ATP Hydrolysis Cycle Restores Wild-Type Function in the Lipopolysaccharide Transporter and Shows that ATP Binding Triggers Transport.
Mbio, 10, 2019
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5NQT
 | | Tubulin Darpin room-temperature structure determined by serial millisecond crystallography | | 分子名称: | DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Weinert, T, Olieric, N, James, D, Gashi, D, Nogly, P, Jaeger, K, Steinmetz, M.O, Standfuss, J. | | 登録日 | 2017-04-21 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.
Nat Commun, 8, 2017
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6ER7
 | | CHEMOTAXIS PROTEIN CHEY FROM Pyrococcus horikoshiI | | 分子名称: | 120aa long hypothetical chemotaxis protein (CheY) | | 著者 | Paithankar, K.S, Enderle, M.E, Wirthensohn, D, Grininger, M, Oesterhelt, D. | | 登録日 | 2017-10-17 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structure of the archaeal chemotaxis protein CheY in a domain-swapped dimeric conformation.
Acta Crystallogr.,Sect.F, 75, 2019
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2C62
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5LPY
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6LZL
 | | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with Piperine | | 分子名称: | (2E,4E)-5-(2H-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | | 著者 | Liu, Z.H, Wu, D, Lu, W.Q, Huang, J. | | 登録日 | 2020-02-19 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with Piperine
To Be Published
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1IKF
 | | A CONFORMATION OF CYCLOSPORIN A IN AQUEOUS ENVIRONMENT REVEALED BY THE X-RAY STRUCTURE OF A CYCLOSPORIN-FAB COMPLEX | | 分子名称: | CYCLOSPORIN A, IGG1-KAPPA R45-45-11 FAB (HEAVY CHAIN), IGG1-KAPPA R45-45-11 FAB (LIGHT CHAIN) | | 著者 | Vix, O, Altschuh, D, Rees, B, Thierry, J.-C. | | 登録日 | 1993-12-09 | | 公開日 | 1995-03-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A Conformation of Cyclosporin a in Aqueous Environment Revealed by the X-Ray Structure of a Cyclosporin-Fab Complex.
Science, 256, 1992
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2C5G
 | | Torpedo californica acetylcholinesterase in complex with 20mM thiocholine | | 分子名称: | 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... | | 著者 | Colletier, J.P, Fournier, D, Greenblatt, H.M, Sussman, J.L, Zaccai, G, Silman, I, Weik, M. | | 登録日 | 2005-10-27 | | 公開日 | 2006-06-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural Insights Into Substrate Traffic and Inhibition in Acetylcholinesterase.
Embo J., 25, 2006
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2C4K
 | | Crystal structure of human phosphoribosylpyrophosphate synthetase- associated protein 39 (PAP39) | | 分子名称: | PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE-ASSOCIATED PROTEIN 1, SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE | | 著者 | Kursula, P, Stenmark, P, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Flodin, S, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Kotenyova, T, Nilsson-Ehle, P, Ogg, D, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Nordlund, P. | | 登録日 | 2005-10-20 | | 公開日 | 2005-10-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal Structure of Human Phosphoribosylpyrophosphate Synthetase-Associated Protein 39 (Pap39)
To be Published
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2C5V
 | | Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design | | 分子名称: | 4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)-N-[4-(TRIFLUOROMETHYL)PHENYL]PYRIMIDIN-2-AMINE, ALA-ALA-ABA-ARG-SER-LEU-ILE-PFF-NH2, CELL DIVISION PROTEIN KINASE 2, ... | | 著者 | Kontopidis, G, McInnes, C, Pandalaneni, S.R, McNae, I, Gibson, D, Mezna, M, Thomas, M, Wood, G, Wang, S, Walkinshaw, M.D, Fischer, P.M. | | 登録日 | 2005-11-02 | | 公開日 | 2006-03-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design.
Chem.Biol., 13, 2006
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2BWO
 | | 5-Aminolevulinate Synthase from Rhodobacter capsulatus in complex with succinyl-CoA | | 分子名称: | 5-AMINOLEVULINATE SYNTHASE, PYRIDOXAL-5'-PHOSPHATE, SUCCINYL-COENZYME A | | 著者 | Astner, I, Schulze, J.O, van den Heuvel, J.J, Jahn, D, Schubert, W.-D, Heinz, D.W. | | 登録日 | 2005-07-15 | | 公開日 | 2005-09-27 | | 最終更新日 | 2015-12-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of 5-Aminolevulinate Synthase, the First Enzyme of Heme Biosynthesis, and its Link to Xlsa in Humans.
Embo J., 24, 2005
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2BIT
 | | Crystal structure of human cyclophilin D at 1.7 A resolution | | 分子名称: | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE | | 著者 | Hennig, M, Thoma, R, Stihle, M, Schlatter, D. | | 登録日 | 2005-01-26 | | 公開日 | 2005-01-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Crystal Engineering Yields Crystals of Cyclophilin D Diffracting to 1.7 A Resolution
Acta Crystallogr.,Sect.D, 61, 2005
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2C5N
 | | Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design | | 分子名称: | CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE | | 著者 | Kontopidis, G, McInnes, C, Pandalaneni, S.R, McNae, I, Gibson, D, Mezna, M, Thomas, M, Wood, G, Wang, S, Walkinshaw, M.D, Fischer, P.M. | | 登録日 | 2005-10-30 | | 公開日 | 2006-03-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design.
Chem.Biol., 13, 2006
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2BDF
 | | Src kinase in complex with inhibitor AP23451 | | 分子名称: | Proto-oncogene tyrosine-protein kinase Src, {[(4-{[2-(4-AMINOCYCLOHEXYL)-9-ETHYL-9H-PURIN-6-YL]AMINO}PHENYL)(HYDROXY)PHOSPHORYL]METHYL}PHOSPHONIC ACID | | 著者 | Dalgarno, D, Stehle, T, Schelling, P, Sawyer, T, Narula, S. | | 登録日 | 2005-10-20 | | 公開日 | 2006-10-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.
Chem.Biol.Drug Des., 67, 2006
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5LNZ
 | | HSP90 WITH indazole derivative | | 分子名称: | Heat shock protein HSP 90-alpha, ~{N}3-butyl-~{N}3,~{N}5-dimethyl-~{N}5-(4-morpholin-4-ylphenyl)-6-oxidanyl-2~{H}-indazole-3,5-dicarboxamide | | 著者 | Graedler, U, Amaral, M, Schuetz, D. | | 登録日 | 2016-08-08 | | 公開日 | 2017-11-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Ligand Desolvation Steers On-Rate and Impacts Drug Residence Time of Heat Shock Protein 90 (Hsp90) Inhibitors.
J. Med. Chem., 61, 2018
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1JBU
 | | Coagulation Factor VII Zymogen (EGF2/Protease) in Complex with Inhibitory Exosite Peptide A-183 | | 分子名称: | BENZAMIDINE, COAGULATION FACTOR VII, Peptide exosite inhibitor A-183, ... | | 著者 | Eigenbrot, C, Kirchhofer, D, Dennis, M.S, Santell, L, Lazarus, R.A, Stamos, J, Ultsch, M.H. | | 登録日 | 2001-06-06 | | 公開日 | 2001-07-11 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The factor VII zymogen structure reveals reregistration of beta strands during activation.
Structure, 9, 2001
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7W26
 | | monolignol ferulate transferase | | 分子名称: | Ferulate monolignol transferase | | 著者 | Xi, L, Shuliu, D, Yue, F, Yi, Z. | | 登録日 | 2021-11-22 | | 公開日 | 2022-03-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Crystal structure of the plant feruloyl-coenzyme A monolignol transferase provides insights into the formation of monolignol ferulate conjugates.
Biochem.Biophys.Res.Commun., 594, 2022
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6LTO
 | | cryo-EM structure of full length human Pannexin1 | | 分子名称: | Pannexin-1 | | 著者 | Mou, L.Q, Ke, M, Xiao, Q.J, Wu, J.P, Deng, D. | | 登録日 | 2020-01-23 | | 公開日 | 2020-05-13 | | 最終更新日 | 2020-05-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis for gating mechanism of Pannexin 1 channel.
Cell Res., 30, 2020
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2BKD
 | | Structure of the N-terminal domain of Fragile X Mental Retardation Protein | | 分子名称: | Fragile X messenger ribonucleoprotein 1 | | 著者 | Ramos, A, Hollingworth, D, Adinolfi, S, Castets, M, Kelly, G, Frenkiel, T.A, Bardoni, B, Pastore, A. | | 登録日 | 2005-02-15 | | 公開日 | 2006-01-18 | | 最終更新日 | 2023-02-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction.
Structure, 14, 2006
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2C7D
 | | Fitted coordinates for GroEL-ADP7-GroES Cryo-EM complex (EMD-1181) | | 分子名称: | 10 KDA CHAPERONIN MOLECULE: GROES, PROTEIN CPN10, GROES PROTEIN, ... | | 著者 | Ranson, N.A, Clare, D.K, Farr, G.W, Houldershaw, D, Horwich, A.L, Saibil, H.R. | | 登録日 | 2005-11-22 | | 公開日 | 2006-01-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (8.7 Å) | | 主引用文献 | Allosteric Signalling of ATP Hydrolysis in Groel-Groes Complexes.
Nat.Struct.Mol.Biol., 13, 2006
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2CO5
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2CI7
 | | Crystal structure of Dimethylarginine Dimethylaminohydrolase I in complex with Zinc, high pH | | 分子名称: | GLYCINE, NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1, ... | | 著者 | Frey, D, Braun, O, Briand, C, Vasak, M, Grutter, M.G. | | 登録日 | 2006-03-17 | | 公開日 | 2006-05-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inhibitors.
Structure, 14, 2006
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2CCC
 | | Complexes of Dodecin with Flavin and Flavin-like Ligands | | 分子名称: | CHLORIDE ION, LUMIFLAVIN, MAGNESIUM ION, ... | | 著者 | Grininger, M, Zeth, K, Oesterhelt, D. | | 登録日 | 2006-01-13 | | 公開日 | 2006-01-31 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Dodecins: A Family of Lumichrome Binding Proteins.
J.Mol.Biol., 357, 2006
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2CGL
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