2C4K

Crystal structure of human phosphoribosylpyrophosphate synthetase- associated protein 39 (PAP39)

Summary for 2C4K

DescriptorPHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE-ASSOCIATED PROTEIN 1, SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, ... (4 entities in total)
Functional Keywordsnucleotide biosynthesis, synthetase, ligase, regulatory protein
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains6
Total molecular weight248051.15
Authors
Primary citation
Kursula, P.,Stenmark, P.,Arrowsmith, C.,Berglund, H.,Edwards, A.,Ehn, M.,Flodin, S.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg Schiavone, L.,Kotenyova, T.,Nilsson-Ehle, P.,Ogg, D.,Persson, C.,Sagemark, J.,Schuler, H.,Sundstrom, M.,Thorsell, A.G.,Van Den Berg, S.,Weigelt, J.,Nordlund, P.
Crystal Structure of Human Phosphoribosylpyrophosphate Synthetase-Associated Protein 39 (Pap39)
To be Published,
Experimental method
X-RAY DIFFRACTION (2.65 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.302132.4%9.4%1.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2c4k
no rotation
Molmil generated image of 2c4k
rotated about x axis by 90°
Molmil generated image of 2c4k
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 2c4k
no rotation
Molmil generated image of 2c4k
rotated about x axis by 90°
Molmil generated image of 2c4k
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2c4k.pdb5.gz [52.68 KB])
Coordinate files for Biological unit (2c4k.pdb2.gz [53.1 KB])
Coordinate files for Biological unit (2c4k.pdb4.gz [52.46 KB])
Coordinate files for Biological unit (2c4k.pdb6.gz [52.35 KB])
Coordinate files for Biological unit (2c4k.pdb3.gz [52.02 KB])
Coordinate files for Biological unit (2c4k.pdb1.gz [51.56 KB])