2C4K

Crystal structure of human phosphoribosylpyrophosphate synthetase- associated protein 39 (PAP39)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004857	molecular_function	enzyme inhibitor activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006015	biological_process	5-phosphoribose 1-diphosphate biosynthetic process
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0006164	biological_process	purine nucleotide biosynthetic process
A	0009165	biological_process	nucleotide biosynthetic process
A	0030234	molecular_function	enzyme regulator activity
A	0042802	molecular_function	identical protein binding
B	0000287	molecular_function	magnesium ion binding
B	0004857	molecular_function	enzyme inhibitor activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0006015	biological_process	5-phosphoribose 1-diphosphate biosynthetic process
B	0006139	biological_process	nucleobase-containing compound metabolic process
B	0006164	biological_process	purine nucleotide biosynthetic process
B	0009165	biological_process	nucleotide biosynthetic process
B	0030234	molecular_function	enzyme regulator activity
B	0042802	molecular_function	identical protein binding
C	0000287	molecular_function	magnesium ion binding
C	0004857	molecular_function	enzyme inhibitor activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0006015	biological_process	5-phosphoribose 1-diphosphate biosynthetic process
C	0006139	biological_process	nucleobase-containing compound metabolic process
C	0006164	biological_process	purine nucleotide biosynthetic process
C	0009165	biological_process	nucleotide biosynthetic process
C	0030234	molecular_function	enzyme regulator activity
C	0042802	molecular_function	identical protein binding
D	0000287	molecular_function	magnesium ion binding
D	0004857	molecular_function	enzyme inhibitor activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0006015	biological_process	5-phosphoribose 1-diphosphate biosynthetic process
D	0006139	biological_process	nucleobase-containing compound metabolic process
D	0006164	biological_process	purine nucleotide biosynthetic process
D	0009165	biological_process	nucleotide biosynthetic process
D	0030234	molecular_function	enzyme regulator activity
D	0042802	molecular_function	identical protein binding
E	0000287	molecular_function	magnesium ion binding
E	0004857	molecular_function	enzyme inhibitor activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0006015	biological_process	5-phosphoribose 1-diphosphate biosynthetic process
E	0006139	biological_process	nucleobase-containing compound metabolic process
E	0006164	biological_process	purine nucleotide biosynthetic process
E	0009165	biological_process	nucleotide biosynthetic process
E	0030234	molecular_function	enzyme regulator activity
E	0042802	molecular_function	identical protein binding
F	0000287	molecular_function	magnesium ion binding
F	0004857	molecular_function	enzyme inhibitor activity
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0006015	biological_process	5-phosphoribose 1-diphosphate biosynthetic process
F	0006139	biological_process	nucleobase-containing compound metabolic process
F	0006164	biological_process	purine nucleotide biosynthetic process
F	0009165	biological_process	nucleotide biosynthetic process
F	0030234	molecular_function	enzyme regulator activity
F	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B1351

Chain	Residue
A	SER344
A	MET345
B	SER54
B	ARG56
E	ARG110

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B1352

Chain	Residue
E	ARG56
B	ARG110
B	SER344
B	MET345
E	SER54

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 C1351

Chain	Residue
C	ARG110
C	GLU343
C	SER344
C	MET345
F	SER54
F	VAL55
F	ARG56

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D1351

Chain	Residue
C	SER54
C	ARG56
D	SER344
D	MET345
F	ARG110

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 E1351

Chain	Residue
A	SER54
A	ARG56
A	ARG110
E	SER344
E	MET345

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 E1352

Chain	Residue
E	ARG90

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 F1351

Chain	Residue
D	SER54
D	ARG56
D	ARG110
F	SER344
F	MET345

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE TAM B1353

Chain	Residue
B	ARG25
B	TYR160
B	LYS324
B	THR325
B	ASP327

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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