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PDB: 52974 件

6W2G
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Crystal Structure of Y188G Variant of the Internal UBA Domain of HHR23A in Monoclinic Unit Cell
分子名称: 1,2-ETHANEDIOL, UV excision repair protein RAD23 homolog A
著者Bowler, B.E, Zeng, B, Becht, D.C, Rothfuss, M, Sprang, S.R, Mou, T.-C.
登録日2020-03-05
公開日2021-03-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献High-Accuracy Prediction of Stabilizing Surface Mutations to the Three-Helix Bundle, UBA(1), with EmCAST.
J.Am.Chem.Soc., 145, 2023
6VZO
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Crystal structure of human PPARgamma ligand binding domain (Protein delipidated by denature and refold)
分子名称: Peroxisome proliferator-activated receptor gamma
著者Shang, J, Kojetin, D.J.
登録日2020-02-28
公開日2021-03-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural mechanism underlying ligand binding and activation of PPAR gamma.
Structure, 29, 2021
3EHF
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Crystal structure of DesKC in complex with AMP-PCP
分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Sensor kinase (YocF protein)
著者Albanesi, D, Alzari, P.M, Buschiazzo, A.
登録日2008-09-12
公開日2009-09-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural plasticity and catalysis regulation of a thermosensor histidine kinase
Proc.Natl.Acad.Sci.USA, 106, 2009
6VZM
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Crystal structure of human PPARgamma ligand binding domain Y473E mutant in complex with Darglitazone
分子名称: (5Z)-5-({4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)propanoyl]phenyl}methylidene)-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma
著者Shang, J, Kojetin, D.J.
登録日2020-02-28
公開日2021-03-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural mechanism underlying ligand binding and activation of PPAR gamma.
Structure, 29, 2021
6VZN
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Crystal structure of human PPARgamma ligand binding domain Y473E mutant
分子名称: Peroxisome proliferator-activated receptor gamma
著者Shang, J, Kojetin, D.J.
登録日2020-02-28
公開日2021-03-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural mechanism underlying ligand binding and activation of PPAR gamma.
Structure, 29, 2021
6VZL
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Crystal structure of human PPARgamma ligand binding domain in complex with GW1929
分子名称: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, Peroxisome proliferator-activated receptor gamma
著者Shang, J, Kojetin, D.J.
登録日2020-02-28
公開日2021-03-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural mechanism underlying ligand binding and activation of PPAR gamma.
Structure, 29, 2021
4ILK
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BU of 4ilk by Molmil
Crystal structure of short chain alcohol dehydrogenase (rspB) from E. coli CFT073 (EFI TARGET EFI-506413) complexed with cofactor NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MANGANESE (II) ION, Starvation sensing protein rspB, ...
著者Lukk, T, Wichelecki, D, Imker, H.J, Gerlt, J.A, Nair, S.K.
登録日2012-12-31
公開日2013-01-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Crystal structure of short chain alcohol dehydrogenase (rspB) from E. coli CFT073 (EFI TARGET EFI-506413) complexed with cofactor NADH
To be Published
1T61
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crystal structure of collagen IV NC1 domain from placenta basement membrane
分子名称: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Vanacore, R.M, Shanmugasundararaj, S, Friedman, D.B, Bondar, O, Hudson, B.G, Sundaramoorthy, M.
登録日2004-05-05
公開日2004-09-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The alpha1.alpha2 network of collagen IV. Reinforced stabilization of the noncollagenous domain-1 by noncovalent forces and the absence of Met-Lys cross-links
J.Biol.Chem., 279, 2004
6W81
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Structure of PEDV main protease bound to potent broad-spectrum non-covalent inhibitor X77
分子名称: MALONIC ACID, N-(4-tert-butylphenyl)-N-[(1R)-2-(cyclohexylamino)-2-oxo-1-(pyridin-3-yl)ethyl]-1H-imidazole-4-carboxamide, Peptidase C30
著者Mesecar, A.D, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-03-20
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献A taxonomically-driven approach to development of potent, broad-spectrum inhibitors of coronavirus main protease including SARS-CoV-2 (COVID-19)
To Be Published
3ZN6
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VP16-VP17 complex, a complex of the two major capsid proteins of bacteriophage P23-77
分子名称: CHLORIDE ION, SODIUM ION, VP16, ...
著者Rissanen, I, Grimes, J.M, Pawlowski, A, Mantynen, S, Harlos, K, Bamford, J.K.H, Stuart, D.I.
登録日2013-02-13
公開日2013-05-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Bacteriophage P23-77 Capsid Protein Structures Reveal the Archetype of an Ancient Branch from a Major Virus Lineage.
Structure, 21, 2013
7AH9
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Substrate-engaged type 3 secretion system needle complex from Salmonella enterica typhimurium - SpaR state 1
分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, LAURYL DIMETHYLAMINE-N-OXIDE, Lipoprotein PrgK, ...
著者Fahrenkamp, D, Goessweiner-Mohr, N, Miletic, S, Wald, J, Marlovits, T.
登録日2020-09-24
公開日2021-03-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Substrate-engaged type III secretion system structures reveal gating mechanism for unfolded protein translocation
Nat Commun, 12, 2021
3ESL
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Crystal structure of the conserved N-terminal domain of the mitotic checkpoint component BUB1
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Checkpoint serine/threonine-protein kinase BUB1
著者Bolanos-Garcia, V.M, Chirgadze, D.Y, Blundell, T.L.
登録日2008-10-06
公開日2009-02-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献The Crystal Structure of the N-Terminal Region of BUB1 Provides Insight into the Mechanism of BUB1 Recruitment to Kinetochores.
Structure, 17, 2009
3ZUZ
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Structure of Shq1p C-terminal domain
分子名称: ISOPROPYL ALCOHOL, PROTEIN SHQ1
著者Walbott, H, Machado-Pinilla, R, Liger, D, Blaud, M, Rety, S, Grozdanov, P.N, Godin, K, vanTilbeurgh, H, Varani, G, Meier, U.T, Leulliot, N.
登録日2011-07-22
公開日2011-11-30
最終更新日2019-02-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The H/Aca Rnp Assembly Factor Shq1 Functions as an RNA Mimic.
Genes Dev., 25, 2011
4RHP
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BU of 4rhp by Molmil
Crystal structure of human COQ9 in complex with a phospholipid, Northeast Structural Genomics Consortium Target HR5043
分子名称: DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, Ubiquinone biosynthesis protein COQ9, mitochondrial
著者Forouhar, F, Lew, S, Seetharaman, J, Wang, H, Lee, D, Kogan, S, Maglaqui, M, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP)
登録日2014-10-02
公開日2014-10-22
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2.393 Å)
主引用文献Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.
Proc.Natl.Acad.Sci.USA, 111, 2014
6VJO
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BU of 6vjo by Molmil
Human parainfluenza virus type 3 fusion glycoprotein N-terminal heptad repeat domain+alpha/beta-VI
分子名称: Fusion glycoprotein F0
著者Outlaw, V.K, Kreitler, D.F, Gellman, S.H.
登録日2020-01-16
公開日2021-04-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Engineering Protease-Resistant Peptides to Inhibit Human Parainfluenza Viral Respiratory Infection.
J.Am.Chem.Soc., 143, 2021
2J1R
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BU of 2j1r by Molmil
Structure of a Streptococcus pneumoniae fucose binding module
分子名称: CALCIUM ION, FUCOLECTIN-RELATED PROTEIN
著者Boraston, A.B, Wang, D, Burke, R.D.
登録日2006-08-15
公開日2006-09-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Blood Group Antigen Recognition by a Streptococcus Pneumoniae Virulence Factor.
J.Biol.Chem., 281, 2006
3ZN4
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VP16, a capsid protein of bacteriophage P23-77 (VP16-type-2)
分子名称: CHLORIDE ION, CITRIC ACID, VP16
著者Rissanen, I, Grimes, J.M, Pawlowski, A, Mantynen, S, Harlos, K, Bamford, J.K.H, Stuart, D.I.
登録日2013-02-13
公開日2013-05-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Bacteriophage P23-77 Capsid Protein Structures Reveal the Archetype of an Ancient Branch from a Major Virus Lineage.
Structure, 21, 2013
1JSU
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BU of 1jsu by Molmil
P27(KIP1)/CYCLIN A/CDK2 COMPLEX
分子名称: CYCLIN A, CYCLIN-DEPENDENT KINASE-2, P27, ...
著者Russo, A.A, Jeffrey, P.D, Pavletich, N.P.
登録日1996-07-03
公開日1997-07-29
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex.
Nature, 382, 1996
3ZJ0
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The human O-GlcNAcase C-terminal domain is a pseudo histone acetyltransferase
分子名称: 1,2-ETHANEDIOL, ACETYL COENZYME *A, ACETYLTRANSFERASE, ...
著者Rao, F.V, Schuettelkopf, A.W, Dorfmueller, H.C, Ferenbach, A.T, Navratilova, I, van Aalten, D.M.F.
登録日2013-01-15
公開日2013-10-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a Bacterial Putative Acetyltransferase Defines the Fold of the Human O-Glcnacase C-Terminal Domain.
Open Biol., 3, 2013
7BOM
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Crystal structure of recombinant horse spleen apo-R52C/E56C/R59C/E63C-Fr immobilized with gold ions.
分子名称: 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ...
著者Hishikawa, Y, Maity, B, Ito, N, Abe, S, Lu, D, Ueno, T.
登録日2020-03-19
公開日2021-01-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Design of Multinuclear Gold Binding Site at the Two-fold Symmetric Interface of the Ferritin Cage
Chem Lett., 49, 2021
6WBA
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BU of 6wba by Molmil
Structure of Mouse Importin alpha MLH1- R470A NLS Peptide Complex
分子名称: DNA mismatch repair protein Mlh1, Importin subunit alpha-1
著者de Barros, A.C, da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M.
登録日2020-03-26
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.151 Å)
主引用文献Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
6WBB
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BU of 6wbb by Molmil
Structure of Mouse Importin alpha - MLH1-E475A NLS peptide complex
分子名称: DNA mismatch repair protein Mlh1, Importin subunit alpha-1
著者De Barros, A.C, Da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M.
登録日2020-03-26
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.663 Å)
主引用文献Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
6WBC
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Structure of Mouse Importin alpha- MLH1-R472K NLS Peptide Complex
分子名称: DNA mismatch repair protein Mlh1, Importin subunit alpha-1
著者de Barros, A.C, da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M.
登録日2020-03-26
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
2IJD
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BU of 2ijd by Molmil
Crystal Structure of the Poliovirus Precursor Protein 3CD
分子名称: Picornain 3C, RNA-directed RNA polymerase, SULFATE ION, ...
著者Marcotte, L.L, Gohara, D.W, Filman, D.J, Hogle, J.M.
登録日2006-09-29
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal structure of poliovirus 3CD: virally-encoded protease and precursor to the RNA-dependent RNA polymerase.
J.Virol., 81, 2007
1KB8
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A COMPARISON OF NMR SOLUTION STRUCTURES OF THE RECEPTOR BINDING DOMAINS OF PSEUDOMONAS AERUGINOSA PILI STRAINS PAO, KB7, AND PAK: IMPLICATIONS FOR RECEPTOR BINDING AND SYNTHETIC VACCINE DESIGN
分子名称: KB7 PILIN, TRANS
著者Campbell, A.P, Mcinnes, C, Hodges, R.S, Sykes, B.D.
登録日1995-10-05
公開日1996-01-29
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Comparison of NMR solution structures of the receptor binding domains of Pseudomonas aeruginosa pili strains PAO, KB7, and PAK: implications for receptor binding and synthetic vaccine design.
Biochemistry, 34, 1995

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