8CX2
| Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 2 | 分子名称: | Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ... | 著者 | Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D. | 登録日 | 2022-05-19 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The structural basis for HIV-1 Vif antagonism of human APOBEC3G. Nature, 615, 2023
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6G5T
| Myoglobin H64V/V68A in the resting state, 1.5 Angstrom resolution | 分子名称: | 1,2-ETHANEDIOL, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Tinzl, M, Hayashi, T, Mori, T, Hilvert, D. | 登録日 | 2018-03-30 | 公開日 | 2018-08-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Capture and characterization of a reactive haem-carbenoid complex in an artificial metalloenzyme Nat Catal, 1, 2018
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7KBA
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8I5E
| Crystal structure of HLA-A*11:01 in complex with KRAS peptide (VVGAGGVGK) | 分子名称: | Beta-2-microglobulin, KRAS-G12wt-9, MHC class I antigen (Fragment) | 著者 | Lu, D, Chen, Y, Jiang, M, Tan, S.G, Chai, Y, Gao, G.F. | 登録日 | 2023-01-25 | 公開日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) Nat Commun, 2023
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5LPM
| Crystal structure of the bromodomain of human Ep300 bound to the inhibitor XDM3d | 分子名称: | ACETATE ION, Histone acetyltransferase p300, ~{N}-[(1~{S},2~{S})-7-chloranyl-2-oxidanyl-1,2,3,4-tetrahydronaphthalen-1-yl]-4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrole -2-carboxamide | 著者 | Huegle, M, Wohlwend, D, Gerhardt, S. | 登録日 | 2016-08-13 | 公開日 | 2017-08-16 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Beyond the BET Family: Targeting CBP/p300 with 4-Acyl Pyrroles. Angew. Chem. Int. Ed. Engl., 56, 2017
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5KCT
| Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with an N-ethyl, 4-chlorobenzyl OBHS-N derivative | 分子名称: | (1R,2S,4R)-N-(4-chlorophenyl)-N-ethyl-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, (1S,2R,4S)-N-(4-chlorophenyl)-N-ethyl-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor, ... | 著者 | Nwachukwu, J.C, Srinivasan, S, Bruno, N.E, Dharmarajan, V, Goswami, D, Kastrati, I, Novick, S, Nowak, J, Zhou, H.B, Boonmuen, N, Zhao, Y, Min, J, Frasor, J, Katzenellenbogen, B.S, Griffin, P.R, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2016-06-07 | 公開日 | 2016-11-16 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nat. Chem. Biol., 13, 2017
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8CX1
| Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 1 | 分子名称: | Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ... | 著者 | Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D. | 登録日 | 2022-05-19 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | The structural basis for HIV-1 Vif antagonism of human APOBEC3G. Nature, 615, 2023
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7Q1Q
| De novo designed homo-dimeric antiparallel helices Homomer-S | 分子名称: | ACETATE ION, Homomer-S | 著者 | Shanmugaratnam, S, Rhys, G.G, Dawson, W.M, Woolfson, D.N, Hocker, B. | 登録日 | 2021-10-20 | 公開日 | 2022-07-20 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | De novo designed peptides for cellular delivery and subcellular localisation. Nat.Chem.Biol., 18, 2022
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6QT9
| Cryo-EM structure of SH1 full particle. | 分子名称: | ORF 24, ORF 25, ORF 31, ... | 著者 | De Colibus, L, Roine, E, Walter, T.S, Ilca, S.L, Wang, X, Wang, N, Roseman, A.M, Bamford, D, Huiskonen, J.T, Stuart, D.I. | 登録日 | 2019-02-22 | 公開日 | 2019-04-10 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Assembly of complex viruses exemplified by a halophilic euryarchaeal virus. Nat Commun, 10, 2019
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4WES
| Nitrogenase molybdenum-iron protein from Clostridium pasteurianum at 1.08 A resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (II) ION, ... | 著者 | Zhang, L.M, Morrison, C.N, Kaiser, J.T, Rees, D.C. | 登録日 | 2014-09-10 | 公開日 | 2015-02-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | Nitrogenase MoFe protein from Clostridium pasteurianum at 1.08 angstrom resolution: comparison with the Azotobacter vinelandii MoFe protein. Acta Crystallogr.,Sect.D, 71, 2015
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7B5G
| Crystal structure of E.coli LexA in complex with nanobody NbSOS3(Nb14527) | 分子名称: | 1,2-ETHANEDIOL, LexA repressor, Nanobody Nb14527, ... | 著者 | Maso, L, Vascon, F, Chinellato, M, Pardon, E, Steyaert, J, Angelini, A, Tondi, D, Cendron, L. | 登録日 | 2020-12-03 | 公開日 | 2022-09-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Nanobodies targeting LexA autocleavage disclose a novel suppression strategy of SOS-response pathway. Structure, 30, 2022
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5TQZ
| Frutapin complexed with alpha-D-glucose | 分子名称: | Frutapin, alpha-D-glucopyranose | 著者 | Sousa, F.D, Guo, J, Coker, A.R, Monteiro-Moreira, A.C.O, Moreira, R.A. | 登録日 | 2016-10-25 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Frutapin, a lectin fromArtocarpus incisa(breadfruit): cloning, expression and molecular insights. Biosci. Rep., 37, 2017
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6H1X
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3G9W
| Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Integrin beta-1D, ... | 著者 | Anthis, N.J, Wegener, K.L, Ye, F, Kim, C, Lowe, E.D, Vakonakis, I, Bate, N, Critchley, D.R, Ginsberg, M.H, Campbell, I.D. | 登録日 | 2009-02-15 | 公開日 | 2009-10-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.165 Å) | 主引用文献 | The structure of an integrin/talin complex reveals the basis of inside-out signal transduction Embo J., 28, 2009
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8PMQ
| Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin | 分子名称: | E3 ubiquitin-protein ligase RMD5, Protein FYV10, Ubiquitin, ... | 著者 | Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A. | 登録日 | 2023-06-29 | 公開日 | 2024-01-03 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies. Mol.Cell, 84, 2024
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6W2E
| Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | 著者 | Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H. | 登録日 | 2020-03-05 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus. Nat Microbiol, 5, 2020
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8HZZ
| GuApiGT (UGT79B74) | 分子名称: | SULFATE ION, apiosyltransferase | 著者 | Wang, H.T, Wang, Z.L, Li, F.D, Ye, M. | 登録日 | 2023-01-10 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Insights into the missing apiosylation step in flavonoid apiosides biosynthesis of Leguminosae plants. Nat Commun, 14, 2023
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3G4F
| Crystal Structure of (+)- -Cadinene Synthase from Gossypium arboreum in complex with 2-fluorofarnesyl diphosphate | 分子名称: | (+)-delta-cadinene synthase isozyme XC1, (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, BETA-MERCAPTOETHANOL, ... | 著者 | Gennadios, H.A, Di Costanzo, L, Christianson, D.W. | 登録日 | 2009-02-03 | 公開日 | 2009-06-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.651 Å) | 主引用文献 | Crystal structure of (+)-delta-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis. Biochemistry, 48, 2009
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5N6M
| Structure of the membrane integral lipoprotein N-acyltransferase Lnt from P. aeruginosa | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Apolipoprotein N-acyltransferase, CITRATE ANION, ... | 著者 | Huang, C.-Y, Boland, C, Howe, N, Wiktor, M, Vogeley, L, Weichert, D, Bailey, J, Olieric, V, Wang, M, Caffrey, M. | 登録日 | 2017-02-15 | 公開日 | 2017-07-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis. Nat Commun, 8, 2017
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7A97
| SARS-CoV-2 Spike Glycoprotein with 2 ACE2 Bound | 分子名称: | Angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Benton, D.J, Wrobel, A.G, Rosenthal, P.B, Gamblin, S.J. | 登録日 | 2020-09-01 | 公開日 | 2020-09-16 | 最終更新日 | 2020-12-16 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion. Nature, 588, 2020
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6GUZ
| Ground state structure of Archaerhodopsin-3 obtained from LCP crystals using a thin-film sandwich at room temperature | 分子名称: | Archaerhodopsin-3, CALCIUM ION, CHLORIDE ION, ... | 著者 | Moraes, I, Judge, P.J, Bada Juarez, J.F, Vinals, J, Axford, D, Watts, A. | 登録日 | 2018-06-19 | 公開日 | 2019-10-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Room temperature structure of the Archaerhodopsin-3 obtained from LCP crystals using a thin-film sandwich To Be Published
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8UHB
| Cryo-EM Structure of the Ro5256390-bound hTA1-Gs heterotrimer signaling complex | 分子名称: | (2R,4S)-4-[(2S)-2-phenylbutyl]-1,3-oxazolidin-2-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zilberg, G, Warren, A.L, Parpounas, A.K, Wacker, D. | 登録日 | 2023-10-08 | 公開日 | 2024-01-10 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Molecular basis of human trace amine-associated receptor 1 activation. Nat Commun, 15, 2024
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3GDG
| Crystal structure of the NADP-dependent mannitol dehydrogenase from Cladosporium herbarum. | 分子名称: | Probable NADP-dependent mannitol dehydrogenase, SODIUM ION | 著者 | Nuess, D, Goettig, P, Magler, I, Denk, U, Breitenbach, M, Schneider, P.B, Brandstetter, H, Simon-Nobbe, B. | 登録日 | 2009-02-24 | 公開日 | 2010-06-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the NADP-dependent mannitol dehydrogenase from Cladosporium herbarum: Implications for oligomerisation and catalysis. Biochimie, 92, 2010
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5H37
| Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C10 IgG heavy chain variable region, C10 IgG light chain variable region, ... | 著者 | Zhang, S, Kostyuchenko, V, Ng, T.-S, Lim, X.-N, Ooi, J.S.G, Lambert, S, Tan, T.Y, Widman, D, Shi, J, Baric, R.S, Lok, S.-M. | 登録日 | 2016-10-20 | 公開日 | 2016-11-30 | 最終更新日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Neutralization mechanism of a highly potent antibody against Zika virus Nat Commun, 7, 2016
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7S23
| Crystal structure of alpha-COP-WD40 domain, Y139A mutant | 分子名称: | Coatomer subunit alpha | 著者 | Dey, D, Singh, S, Khan, S, Martin, M, Schnicker, N, Gakhar, L, Pierce, B, Hasan, S.S. | 登録日 | 2021-09-03 | 公開日 | 2022-02-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking Commun Biol, 5, 2022
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