5MN7
| S. aureus FtsZ 12-316 F138A GTP Closed form (3FCm) | 分子名称: | Cell division protein FtsZ, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | 著者 | Wagstaff, J.M, Tsim, M, Kureisaite-Ciziene, D, Lowe, J. | 登録日 | 2016-12-12 | 公開日 | 2017-01-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | A Polymerization-Associated Structural Switch in FtsZ That Enables Treadmilling of Model Filaments. MBio, 8, 2017
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4XYF
| Crystal structure of c-Met in complex with (S)-5-(8-fluoro-3-(1-(3-(2-methoxyethoxy)quinolin-6-yl)ethyl)-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-3-methylisoxazole | 分子名称: | 6-{(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(2-methoxyethoxy)quinoline, Hepatocyte growth factor receptor | 著者 | Whittington, D.A, Long, A.M. | 登録日 | 2015-02-02 | 公開日 | 2015-03-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Discovery of Potent and Selective 8-Fluorotriazolopyridine c-Met Inhibitors. J.Med.Chem., 58, 2015
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7KUI
| Cryo-EM structure of Rous sarcoma virus cleaved synaptic complex (CSC) with HIV-1 integrase strand transfer inhibitor MK-2048. CIC region of a cluster identified by 3-dimensional variability analysis in cryoSPARC. | 分子名称: | (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*GP*CP*AP*TP*AP*AP*GP*AP*CP*AP*AP*CP*A)-3'), ... | 著者 | Pandey, K.K, Bera, S, Shi, K, Aihara, H, Grandgenett, D.P. | 登録日 | 2020-11-25 | 公開日 | 2021-03-17 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome. Commun Biol, 4, 2021
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6FHS
| CryoEM Structure of INO80core | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Arp5, ... | 著者 | Eustermann, S, Schall, K, Kostrewa, D, Strauss, M, Hopfner, K. | 登録日 | 2018-01-15 | 公開日 | 2018-04-25 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.754 Å) | 主引用文献 | Structural basis for ATP-dependent chromatin remodelling by the INO80 complex. Nature, 556, 2018
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3IFP
| X-ray structure of amyloid beta peptide:antibody (Abeta1-7:12B4) complex | 分子名称: | 12B4 FAB antibody heavy chain, 12B4 FAB antibody light chain, Amyloid beta A4 protein | 著者 | Weis, W.I, Feinberg, H, Basi, G.S, Schenk, D. | 登録日 | 2009-07-24 | 公開日 | 2009-11-17 | 最終更新日 | 2013-09-25 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease. J.Biol.Chem., 285, 2010
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7KU7
| Cryo-EM structure of Rous sarcoma virus cleaved synaptic complex (CSC) with HIV-1 integrase strand transfer inhibitor MK-2048. Cluster identified by 3-dimensional variability analysis in cryoSPARC. | 分子名称: | (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*GP*CP*AP*TP*AP*AP*GP*AP*CP*AP*AP*CP*A)-3'), ... | 著者 | Pandey, K.K, Bera, S, Shi, K, Aihara, H, Grandgenett, D.P. | 登録日 | 2020-11-24 | 公開日 | 2021-03-17 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome. Commun Biol, 4, 2021
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7SXK
| Kinetically trapped Pseudomonas-phage PaP3 portal protein - Full Length | 分子名称: | Portal protein | 著者 | Hou, C.F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G. | 登録日 | 2021-11-23 | 公開日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3. J.Mol.Biol., 434, 2022
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5FQ8
| Crystal structure of the SusCD complex BT2261-2264 from Bacteroides thetaiotaomicron | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 3-decanoyloxypropyl decanoate, BT_2262 (UNCHARACTERISED LIPOPROTEIN), ... | 著者 | Glenwright, A.J, Pothula, K.R, Chorev, D.S, Basle, A, Robinson, C.V, Kleinekathoefer, U, Bolam, D.N, van den Berg, B. | 登録日 | 2015-12-07 | 公開日 | 2016-12-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural basis for nutrient acquisition by dominant members of the human gut microbiota. Nature, 541, 2017
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8H2D
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8UCX
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5MVD
| Crystal structure of potent human Dihydroorotate Dehydrogenase inhibitors based on hydroxylated azole scaffolds | 分子名称: | 1,5-dimethyl-3-oxidanyl-~{N}-[2,3,5,6-tetrakis(fluoranyl)-4-phenyl-phenyl]pyrazole-4-carboxamide, ACETATE ION, CHLORIDE ION, ... | 著者 | Goyal, P, Andersson, M, Moritzer, A.C, Sainas, S, Pippione, A.C, Boschi, D, Al-Kadaraghi, S, Lolli, M, Friemann, R. | 登録日 | 2017-01-16 | 公開日 | 2017-03-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds. Eur J Med Chem, 129, 2017
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7T5A
| Crystal structure of the molybdate-binding periplasmic protein ModA from the bacteria Pseudomonsa aeruginosa in tungstate-bound form | 分子名称: | AMMONIUM ION, Molybdate-binding periplasmic protein ModA, TUNGSTATE(VI)ION | 著者 | Ngu, D.H.Y, Luo, Z, Lim, B.Y.J, Kobe, B. | 登録日 | 2021-12-11 | 公開日 | 2022-05-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis. Front Microbiol, 13, 2022
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7OJT
| Crystal structure of unliganded PatA, a membrane associated acyltransferase from Mycobacterium smegmatis | 分子名称: | GLYCEROL, Phosphatidylinositol mannoside acyltransferase | 著者 | Anso, I, Wang, L, Marina, A, Paez-Perez, E.D, Perrone, S, Lowary, T.L, Trastoy, B, Guerin, M.E. | 登録日 | 2021-05-17 | 公開日 | 2021-10-27 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.67 Å) | 主引用文献 | Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA. Sci Adv, 7, 2021
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5K3G
| Crystals structure of Acyl-CoA oxidase-1 in Caenorhabditis elegans, Apo form-I | 分子名称: | Acyl-coenzyme A oxidase | 著者 | Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A. | 登録日 | 2016-05-19 | 公開日 | 2016-08-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.859 Å) | 主引用文献 | Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans. Proc.Natl.Acad.Sci.USA, 113, 2016
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5K4F
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7T4Z
| Crystal structure of the molybdate-binding periplasmic protein ModA from the bacteria Pseudomonsa aeruginosa in ligand-free form | 分子名称: | AMMONIUM ION, GLYCEROL, Molybdate-binding periplasmic protein, ... | 著者 | Ngu, D.H.Y, Luo, Z, Lim, B.Y.J, Kobe, B. | 登録日 | 2021-12-10 | 公開日 | 2022-05-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis. Front Microbiol, 13, 2022
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5CNQ
| Crystal structure of the Holliday junction-resolving enzyme GEN1 (WT) in complex with product DNA, Mg2+ and Mn2+ ions | 分子名称: | DNA (5'-D(*TP*GP*AP*GP*CP*GP*GP*TP*GP*GP*TP*TP*GP*GP*T)-3'), MANGANESE (II) ION, Nuclease-like protein, ... | 著者 | Liu, Y.J, Freeman, A.D.J, Declais, A.C, Wilson, T.J, Gartner, A, Lilley, D.M.J. | 登録日 | 2015-07-17 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | 主引用文献 | Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA. Cell Rep, 13, 2015
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8C0H
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7T50
| Crystal structure of the molybdate-binding periplasmic protein ModA from the bacteria Pseudomonsa aeruginosa in chromate-bound form | 分子名称: | AMMONIUM ION, Chromate, GLYCEROL, ... | 著者 | Ngu, D.H.Y, Luo, Z, Lim, B.Y.J, Kobe, B. | 登録日 | 2021-12-11 | 公開日 | 2022-05-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis. Front Microbiol, 13, 2022
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6FDW
| Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-356 | 分子名称: | (4aS,8aR)-2-(1-{2-aminothieno[2,3-d]pyrimidin-4-yl}piperidin-4-yl)-4-(3,4- dimethoxyphenyl)-1,2,4a,5,8,8a-hexahydrophthalazin-1-one, GLYCEROL, GUANIDINE, ... | 著者 | Singh, A.K, Brown, D.G. | 登録日 | 2017-12-27 | 公開日 | 2019-04-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | TbrPDEB1 structure with inhibitor NPD-356 To be published
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7QE7
| High-resolution structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1 | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | 著者 | Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D. | 登録日 | 2021-12-01 | 公開日 | 2022-01-26 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1 To Be Published
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7T51
| Crystal structure of the molybdate-binding periplasmic protein ModA from the bacteria Pseudomonsa aeruginosa in molybdate-bound form | 分子名称: | AMMONIUM ION, GLYCEROL, MOLYBDATE ION, ... | 著者 | Ngu, D.H.Y, Luo, Z, Lim, B.Y.J, Kobe, B. | 登録日 | 2021-12-11 | 公開日 | 2022-05-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis. Front Microbiol, 13, 2022
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8P27
| Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, dATP-bound state | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, MAGNESIUM ION | 著者 | Banerjee, I, Bimai, O, Sjoberg, B.M, Logan, D.T. | 登録日 | 2023-05-15 | 公開日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Activity modulation in anaerobic ribonucleotide reductases: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site Elife, 2023
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7OCD
| Resting state GluA1/A2 heterotetramer in complex with auxiliary subunit TARP gamma 8 (LBD-TMD) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, Glutamate receptor 2, ... | 著者 | Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H. | 登録日 | 2021-04-26 | 公開日 | 2021-06-09 | 最終更新日 | 2021-06-30 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Gating and modulation of a hetero-octameric AMPA glutamate receptor. Nature, 594, 2021
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6FKP
| Crystal structure of BAZ2A PHD zinc finger in complex with H3 10-mer AA mutant peptide | 分子名称: | ALA-ARG-THR-ALA-ALA-THR-ALA-ARG, Bromodomain adjacent to zinc finger domain protein 2A, GLYCEROL, ... | 著者 | Amato, A, Lucas, X, Bortoluzzi, A, Wright, D, Ciulli, A. | 登録日 | 2018-01-24 | 公開日 | 2018-03-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach. ACS Chem. Biol., 13, 2018
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