Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 53526 件
6V36
DownloadVisualize
BU of 6v36 by Molmil
K2P2.1(TREK-1)I110D apo channel structure
分子名称: CADMIUM ION, N-OCTANE, POTASSIUM ION, ...
著者Pope, L, Lolicato, M, Minor, D.L.
登録日2019-11-25
公開日2020-02-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Polynuclear Ruthenium Amines Inhibit K2PChannels via a "Finger in the Dam" Mechanism.
Cell Chem Biol, 2020
4X9T
DownloadVisualize
BU of 4x9t by Molmil
Crystal structure of a TctC solute binding protein from Polaromonas (Bpro_3516, Target EFI-510338), no ligand
分子名称: CHLORIDE ION, Uncharacterized protein UPF0065
著者Yadava, U, Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2014-12-11
公開日2014-12-24
最終更新日2015-02-11
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Crystal structure of a TctC solute binding protein from Polaromonas (Bpro_3516, Target EFI-510338), no ligand
To be published
4QJK
DownloadVisualize
BU of 4qjk by Molmil
Crystal structure of M. tuberculosis phosphopantetheinyl transferase PptT
分子名称: COENZYME A, Phosphopantetheinyl transferase PptT, SULFATE ION
著者Noel, J.P, Burkart, M.D, Vickery, C.R.
登録日2014-06-04
公開日2014-07-16
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of mycobacteria.
Acs Chem.Biol., 9, 2014
3LEV
DownloadVisualize
BU of 3lev by Molmil
HIV-1 antibody 2F5 in complex with epitope scaffold ES2
分子名称: 2F5 ANTIBODY HEAVY CHAIN, 2F5 ANTIBODY LIGHT CHAIN, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Ofek, G, Guenaga, F.J, Schief, W.R, Skinner, J, Baker, D, Wyatt, R, Kwong, P.D.
登録日2010-01-15
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Elicitation of structure-specific antibodies by epitope scaffolds.
Proc.Natl.Acad.Sci.USA, 107, 2010
8AJ2
DownloadVisualize
BU of 8aj2 by Molmil
structure of the ordered core of Knr4 (loop 189-217 deleted)
分子名称: Structured core of Knr4
著者Caisso, A, Donker, E.I.M, Maveyraud, L, Zerbib, D.
登録日2022-07-27
公開日2023-04-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Conserved Yeast Protein Knr4 Involved in Cell Wall Integrity Is a Multi-domain Intrinsically Disordered Protein.
J.Mol.Biol., 435, 2023
7QW5
DownloadVisualize
BU of 7qw5 by Molmil
Adenine-specific DNA methyltransferase M.BseCI complexed with AdoHcy and cognate unmethylated DNA duplex
分子名称: Modification methylase BseCI, S-ADENOSYL-L-HOMOCYSTEINE, Unmethylated DNA duplex
著者Mitsikas, D.A, Kouyianou, K, Kotsifaki, D, Providaki, M, Bouriotis, V, Glykos, N.M, Kokkinidis, M.
登録日2022-01-24
公開日2023-01-25
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of M.BseCI DNA methyltransferase from Geobacillus stearothermophilus.
To Be Published
7A2A
DownloadVisualize
BU of 7a2a by Molmil
Crystal Structure of EGFR-T790M/V948R in Complex with Spebrutinib and EAI001
分子名称: (2R)-2-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)-2-phenyl-N-(1,3-thiazol-2-yl)acetamide, CHLORIDE ION, Epidermal growth factor receptor, ...
著者Niggenaber, J, Mueller, M.P, Rauh, D.
登録日2020-08-17
公開日2020-11-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Complex Crystal Structures of EGFR with Third-Generation Kinase Inhibitors and Simultaneously Bound Allosteric Ligands.
Acs Med.Chem.Lett., 11, 2020
4QIM
DownloadVisualize
BU of 4qim by Molmil
Structure of the human smoothened receptor in complex with ANTA XV
分子名称: 2-{6-[4-(4-benzylphthalazin-1-yl)piperazin-1-yl]pyridin-3-yl}propan-2-ol, Smoothened homolog/Soluble cytochrome b562 chimeric protein, ZINC ION
著者Wang, C, Wu, H, Evron, T, Vardy, E, Han, G.W, Huang, X.-P, Hufeisen, S.J, Mangano, T.J, Urban, D.J, Katritch, V, Cherezov, V, Caron, M.G, Roth, B.L, Stevens, R.C, GPCR Network (GPCR)
登録日2014-05-31
公開日2014-07-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs.
Nat Commun, 5, 2014
4XLG
DownloadVisualize
BU of 4xlg by Molmil
C. glabrata Slx1 in complex with Slx4CCD.
分子名称: CHLORIDE ION, Structure-specific endonuclease subunit SLX1, Structure-specific endonuclease subunit SLX4, ...
著者Gaur, V, Wyatt, H.D.M, Komorowska, W, Szczepanowski, R.H, de Sanctis, D, Gorecka, K.M, West, S.C, Nowotny, M.
登録日2015-01-13
公開日2015-03-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease.
Cell Rep, 10, 2015
8ITS
DownloadVisualize
BU of 8its by Molmil
Crystal structure of DUF-3268 k-junction
分子名称: MAGNESIUM ION, RNA (46-MER)
著者Li, M, Lilley, D.M.J, Huang, L.
登録日2023-03-22
公開日2024-03-27
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal structure of DUF-3268 k-junction
To Be Published
6RA0
DownloadVisualize
BU of 6ra0 by Molmil
A ubiquitin-like dimerization domain controls protein kinase D activation by trans-autophosphorylation
分子名称: Serine/threonine-protein kinase dkf-1, ZINC ION
著者Elsner, D.J, Leonard, T.A.
登録日2019-04-05
公開日2019-08-14
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献A ubiquitin-like domain controls protein kinase D dimerization and activation by trans-autophosphorylation.
J.Biol.Chem., 294, 2019
6E1T
DownloadVisualize
BU of 6e1t by Molmil
Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 1: 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine, MAGNESIUM ION, ...
著者Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R.
登録日2018-07-10
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure.
Nat Commun, 10, 2019
6I1K
DownloadVisualize
BU of 6i1k by Molmil
Crystal structure of catalytically inactive FnCas12a in complex with a crRNA guide and a dsDNA target
分子名称: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas12a, DNA non-target strand (33-MER), ...
著者Jinek, M, Swarts, D.C.
登録日2018-10-29
公開日2019-01-23
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a.
Mol. Cell, 73, 2019
6LA9
DownloadVisualize
BU of 6la9 by Molmil
349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 (high cryoprotectant)
分子名称: CALCIUM ION, DNA (349-MER), Histone H1.0, ...
著者Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A.
登録日2019-11-12
公開日2020-10-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Near-atomic resolution structures of interdigitated nucleosome fibres.
Nat Commun, 11, 2020
6E1U
DownloadVisualize
BU of 6e1u by Molmil
Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 2: 2-[(dibenzo[b,d]furan-2-yl)oxy]-N,N-dimethylethan-1-amine
分子名称: 2-[(dibenzo[b,d]furan-2-yl)oxy]-N,N-dimethylethan-1-amine, MAGNESIUM ION, RNA (33-MER)
著者Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R.
登録日2018-07-10
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure.
Nat Commun, 10, 2019
7QW6
DownloadVisualize
BU of 7qw6 by Molmil
Adenine-specific DNA methyltransferase M.BseCI complexed with AdoHcy and cognate hemimethylated DNA duplex
分子名称: Hemimethylated DNA duplex, Modification methylase BseCI, S-ADENOSYL-L-HOMOCYSTEINE
著者Mitsikas, D.A, Kouyianou, K, Kotsifaki, D, Providaki, M, Bouriotis, V, Glykos, N.M, Kokkinidis, M.
登録日2022-01-24
公開日2023-01-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of M.BseCI DNA methyltransferase from Geobacillus stearothermophilus.
To Be Published
7QW8
DownloadVisualize
BU of 7qw8 by Molmil
Adenine-specific DNA methyltransferase M.BseCI
分子名称: Modification methylase BseCI
著者Mitsikas, D.A, Kouyianou, K, Kotsifaki, D, Providaki, M, Bouriotis, V, Glykos, N.M, Kokkinidis, M.
登録日2022-01-24
公開日2023-01-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of M.BseCI DNA methyltransferase from Geobacillus stearothermophilus.
To Be Published
8Q9A
DownloadVisualize
BU of 8q9a by Molmil
Tau - CTE-MIA11 (tau intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-20
公開日2023-09-20
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
4XIW
DownloadVisualize
BU of 4xiw by Molmil
Carbonic anhydrase Cah3 from Chlamydomonas reinhardtii in complex with acetazolamide
分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase, alpha type, ...
著者Hainzl, T, Grundstrom, C, Benlloch, R, Shevela, D, Shutova, T, Messinger, J, Samuelsson, G, Sauer-Eriksson, A.E.
登録日2015-01-07
公開日2015-02-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure and Functional Characterization of Photosystem II-Associated Carbonic Anhydrase CAH3 in Chlamydomonas reinhardtii.
Plant Physiol., 167, 2015
8Q8X
DownloadVisualize
BU of 8q8x by Molmil
Tau - CTE-MIA5 (tau intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-19
公開日2023-09-20
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (2.54 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q9B
DownloadVisualize
BU of 8q9b by Molmil
Tau - CTE-MIA13 (tau intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-20
公開日2023-09-20
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8AV9
DownloadVisualize
BU of 8av9 by Molmil
INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN FABCOMPLEX IN COMPLEX WITH COMPOUND 1
分子名称: (3R,6R,7S,8E,11S,12R,22S)-6'-chloro-7-methoxy-11,12-dimethyl-13,13-dioxo-spiro[20-oxa-13-gamma6-thia-1,14-diazatetracyclo[14.7.2.03,6.019,24]pentacosa-8,16(25),17,19(24)-tetraene-22,1'-tetralin]-15-one, Fab Heavy Chain, Fab Light Chain, ...
著者Hargreaves, D.
登録日2022-08-26
公開日2023-05-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Design of rigid protein-protein interaction inhibitors enables targeting of undruggable Mcl-1.
Proc.Natl.Acad.Sci.USA, 120, 2023
3LD7
DownloadVisualize
BU of 3ld7 by Molmil
Crystal structure of the Lin0431 protein from Listeria innocua, Northeast Structural Genomics Consortium Target LkR112
分子名称: Lin0431 protein
著者Vorobiev, S, Chen, Y, Lee, D, Patel, D.J, Ciccosanti, C, Sahdev, S, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2010-01-12
公開日2010-01-26
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.547 Å)
主引用文献Crystal structure of the Lin0431 protein from Listeria innocua
To be Published
101D
DownloadVisualize
BU of 101d by Molmil
REFINEMENT OF NETROPSIN BOUND TO DNA: BIAS AND FEEDBACK IN ELECTRON DENSITY MAP INTERPRETATION
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(CBR)P*GP*CP*G)-3'), MAGNESIUM ION, NETROPSIN
著者Goodsell, D.S, Kopka, M.L, Dickerson, R.E.
登録日1994-12-14
公開日1995-02-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Refinement of netropsin bound to DNA: bias and feedback in electron density map interpretation.
Biochemistry, 34, 1995
101M
DownloadVisualize
BU of 101m by Molmil
SPERM WHALE MYOGLOBIN F46V N-BUTYL ISOCYANIDE AT PH 9.0
分子名称: MYOGLOBIN, N-BUTYL ISOCYANIDE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Smith, R.D, Olson, J.S, Phillips Jr, G.N.
登録日1997-12-13
公開日1998-04-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Correlations between Bound N-Alkyl Isocyanide Orientations and Pathways for Ligand Binding in Recombinant Myoglobins
Thesis, Rice, 1999

225946

件を2024-10-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon