Crystal structure of M. tuberculosis phosphopantetheinyl transferase PptT

Summary for 4QJK

DescriptorPhosphopantetheinyl transferase PptT, COENZYME A, SULFATE ION, ... (4 entities in total)
Functional Keywordsphosphopantetheinyl transferase, coa binding, transferase
Biological sourceMycobacterium tuberculosis
Total number of polymer chains1
Total molecular weight26955.88
Noel, J.P.,Burkart, M.D.,Vickery, C.R. (deposition date: 2014-06-04, release date: 2014-07-16, Last modification date: 2017-11-22)
Primary citation
Vickery, C.R.,Kosa, N.M.,Casavant, E.P.,Duan, S.,Noel, J.P.,Burkart, M.D.
Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of mycobacteria.
Acs Chem.Biol., 9:1939-1944, 2014
PubMed: 24963544 (PDB entries with the same primary citation)
DOI: 10.1021/cb500263p
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.205200.5%2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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