4Z6Z
 
 | | Structure of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum in complex with 4-sulfonyl catechol at 1.52 Ang resolution | | 分子名称: | 3,4-dihydroxybenzenesulfonic acid, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CALCIUM ION, ... | | 著者 | Kovaleva, E.G, Lipscomb, J.D. | | 登録日 | 2015-04-06 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200.
Biochemistry, 54, 2015
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8Q6F
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8Q6H
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8ABQ
 | | Structure of the SNX1-SNX5 complex, Pt derivative | | 分子名称: | PLATINUM (II) ION, Sorting nexin-1, Sorting nexin-5 | | 著者 | Lopez-Robles, C, Scaramuzza, S, Astorga-Simon, E.N, Banos-Mateos, S, Vidaurrazaga, A, Rojas, A.L, Castano, D, Hierro, A. | | 登録日 | 2022-07-04 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Architecture of the ESCPE-1 membrane coat.
Nat.Struct.Mol.Biol., 30, 2023
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8AFZ
 | | Architecture of the ESCPE-1 membrane coat | | 分子名称: | Cation-independent mannose-6-phosphate receptor, Sorting nexin-1, Sorting nexin-5 | | 著者 | Lopez-Robles, C, Scaramuzza, S, Astorga-Simon, E, Ishida, M, Williamsom, C.D, Banos-Mateos, S, Gil-Carton, D, Romero, M, Vidaurrazaga, A, Fernandez-Recio, J, Rojas, A.L, Bonifacino, J.S, Castano-Diez, D, Hierro, A. | | 登録日 | 2022-07-18 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (10 Å) | | 主引用文献 | Architecture of the ESCPE-1 membrane coat.
Nat.Struct.Mol.Biol., 30, 2023
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3H6I
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4ZBJ
 | | UBN1 peptide bound to H3.3/H4/Asf1 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Histone H3, ... | | 著者 | Marmorstein, R, Ricketts, M.D, Tang, Y. | | 登録日 | 2015-04-14 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.248 Å) | | 主引用文献 | Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex.
Nat Commun, 6, 2015
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6CYM
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4Z18
 | | CRYSTAL STRUCTURE OF HUMAN PD-L1 | | 分子名称: | CHLORIDE ION, Programmed cell death 1 ligand 1 | | 著者 | Fedorov, A.A, Fedorov, E.V, Samantha, D, Hillerich, B, Seidel, R.D, Almo, S.C. | | 登録日 | 2015-03-27 | | 公開日 | 2015-04-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF HUMAN PD-L1
To Be Published
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7KRA
 | | Cryo-EM structure of Saccharomyces cerevisiae ER membrane protein complex bound to Fab-DH4 in lipid nanodiscs | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ER membrane protein complex subunit 1, ER membrane protein complex subunit 2, ... | | 著者 | Miller-Vedam, L.E, Schirle Oakdale, N.S, Braeuning, B, Boydston, E.A, Sevillano, N, Popova, K.D, Bonnar, J.L, Shurtleff, M.J, Prabu, J.R, Stroud, R.M, Craik, C.S, Schulman, B.A, Weissman, J.S, Frost, A. | | 登録日 | 2020-11-19 | | 公開日 | 2020-12-02 | | 最終更新日 | 2020-12-09 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.
Elife, 9, 2020
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4ZCW
 | | Structure of Human Enolase 2 in complex with SF2312 | | 分子名称: | Gamma-enolase, MAGNESIUM ION, [(3S,5S)-1,5-dihydroxy-2-oxopyrrolidin-3-yl]phosphonic acid | | 著者 | Leonard, P.G, Maxwell, D, Czako, B, Muller, F.L. | | 登録日 | 2015-04-16 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.992 Å) | | 主引用文献 | SF2312 is a natural phosphonate inhibitor of enolase.
Nat.Chem.Biol., 12, 2016
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6CPR
 | | Crystal structure of 4-1BBL/4-1BB complex in C2 space group | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | | 著者 | Aruna, B, Zajonc, D.M. | | 登録日 | 2018-03-14 | | 公開日 | 2018-05-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier.
J. Biol. Chem., 293, 2018
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7KIR
 | | Crystal structure of inositol polyphosphate 1-phosphatase (INPP1) D54A mutant in complex with inositol (1,4)-bisphosphate | | 分子名称: | CALCIUM ION, D-MYO-INOSITOL-1,4-BISPHOSPHATE, Inositol polyphosphate 1-phosphatase | | 著者 | Dollins, D.E, Xiong, J.-P, Ren, Y, York, J.D. | | 登録日 | 2020-10-24 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A structural basis for lithium and substrate binding of an inositide phosphatase.
J.Biol.Chem., 296, 2020
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7V0K
 | | Consensus refinement of human erythrocyte ankyrin-1 complex (Composite map) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Ammonium transporter Rh type A, Ankyrin-1, ... | | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | | 登録日 | 2022-05-10 | | 公開日 | 2022-07-20 | | 最終更新日 | 2022-07-27 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
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4ZQ8
 | | Crystal structure of a terpene synthase from Streptomyces lydicus, target EFI-540129 | | 分子名称: | Isoprenoid Synthase | | 著者 | Toro, R, Bhosle, R, Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Poulter, C.D, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2015-05-08 | | 公開日 | 2015-07-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of a terpene synthase from Streptomyces lydicus, target EFI-540129
To be published
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7LYW
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8AVY
 | | The ABCB1 L335C mutant (mABCB1) in the Apo state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent translocase ABCB1, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Parey, K, Januliene, D, Gewering, T, Moeller, A. | | 登録日 | 2022-08-27 | | 公開日 | 2023-09-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Tracing the substrate translocation mechanism in P-glycoprotein.
Elife, 12, 2024
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5BR8
 | | Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Sierra, R.G, Gati, C, Laksmono, H, Dao, E.H, Gul, S, Fuller, F, Kern, J, Chatterjee, R, Ibrahim, M, Brewster, A, Young, I.D, Michels-Clark, T, Aquila, A, Mengning, L, Hunter, M.S, Koglin, J.E, Boutet, S, Junco, E.A, Hayes, B, Bogan, M.J, Hampton, C.Y, Puglisi, E.V, Sauter, N.K, Stan, C.A, Zouni, A, Yano, J, Yachandra, V.K, Soltis, S.M, Puglisi, J.D, DeMirci, H. | | 登録日 | 2015-05-29 | | 公開日 | 2015-11-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin
To Be Published
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4YY8
 | | Crystal Structure Analysis of Kelch protein from Plasmodium falciparum | | 分子名称: | GLYCEROL, Kelch protein, UNKNOWN ATOM OR ION | | 著者 | Jiang, D.Q, Tempel, W, Loppnau, P, Graslund, S, He, H, Ravichandran, M, Seitova, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, El Bakkouri, M, Senisterra, G, Osman, K.T, Lovato, D.V, Hui, R, Hutchinson, A, Lin, Y.H, Structural Genomics Consortium (SGC) | | 登録日 | 2015-03-23 | | 公開日 | 2015-04-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Crystal Structure Analysis of Kelch protein from Plasmodium falciparum.
to be published
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2Q7Y
 | | Structure of the endogenous iNKT cell ligand iGb3 bound to mCD1d | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | | 著者 | Zajonc, D.M, Wilson, I.A, Teyton, L. | | 登録日 | 2007-06-07 | | 公開日 | 2008-04-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Valpha14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids.
J.Mol.Biol., 377, 2008
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5AO4
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5AMN
 | | The Discovery of 2-Substituted Phenol Quinazolines as Potent and Selective RET Kinase Inhibitors | | 分子名称: | 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET | | 著者 | Newton, R, Bowler, K, Burns, E.M, Chapman, P, Fairweather, E, Fritzl, S, Goldberg, K, Hamilton, N.M, Holt, S.V, Hopkins, G.V, Jones, S.D, Jordan, A.M, Lyons, A, McDonald, N.Q, Maguire, L.A, Mould, D.P, Purkiss, A.G, Small, H.F, Stowell, A, Thomson, G.J, Waddell, I.D, Waszkowycz, B, Watson, A.J, Ogilvie, D.J. | | 登録日 | 2015-03-11 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity.
Eur J Med Chem, 112, 2016
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5AQD
 | | Crystal structure of Phormidium Phycoerythrin at pH 8.5 | | 分子名称: | GLYCEROL, PHYCOERYTHRIN ALPHA SUBUNIT, PHYCOERYTHRIN BETA SUBUNIT, ... | | 著者 | Kumar, V, Sharma, M, Sonani, R.R, Gupta, G.D, Madamwar, D. | | 登録日 | 2015-09-22 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.121 Å) | | 主引用文献 | Crystal Structure Analysis of C-Phycoerythrin from Marine Cyanobacterium Phormidium Sp. A09Dm.
Photosynth.Res., 129, 2016
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3K9V
 | | Crystal structure of rat mitochondrial P450 24A1 S57D in complex with CHAPS | | 分子名称: | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ... | | 著者 | Annalora, A.J, Goodin, D.B, Hong, W, Zhang, Q, Johnson, E.F, Stout, C.D. | | 登録日 | 2009-10-16 | | 公開日 | 2009-12-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism.
J.Mol.Biol., 396, 2010
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5AQQ
 | | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 7-methylquinazolin-4-amine, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, ... | | 著者 | Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M. | | 登録日 | 2015-09-22 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Sci Rep, 6, 2016
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