6CYM

Reversible Covalent Direct Thrombin Inhibitors

Summary for 6CYM

• Entry DOI: 10.2210/pdb6cym/pdb
• Descriptor: Prothrombin, 2-methoxybenzoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: hydrolase, blood coagulation, plasma, calcium-binding, glycoprotein, serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 66739.35

Authors

Sivaraja, M.,Williams, D.C. (deposition date: 2018-04-06, release date: 2018-05-09, Last modification date: 2020-07-29)

• Primary citation: Sivaraja, M.,Pozzi, N.,Rienzo, M.,Lin, K.,Shiau, T.P.,Clemens, D.M.,Igoudin, L.,Zalicki, P.,Chang, S.S.,Estiarte, M.A.,Short, K.M.,Williams, D.C.,Datta, A.,Di Cera, E.,Kita, D.B.; Reversible covalent direct thrombin inhibitors.; PLoS ONE, 13:e0201377-e0201377, 2018; PubMed: 30071045; DOI: 10.1371/journal.pone.0201377

Experimental method

X-RAY DIFFRACTION (2.9 Å)