7KRA

Cryo-EM structure of Saccharomyces cerevisiae ER membrane protein complex bound to Fab-DH4 in lipid nanodiscs

Summary for 7KRA

• Entry DOI: 10.2210/pdb7kra/pdb
• EMDB information: 11732 11733 23003 23033
• Descriptor: ER membrane protein complex subunit 1, Fab DH4 light chain, Unassigned helix, ... (13 entities in total)
• Functional Keywords: er membrane protein complex, emc, membrane protein biogenesis, insertase, chaperone, endoplasmic, reticulum, membrane protein-immune system complex, membrane protein/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 311507.80

Authors

Miller-Vedam, L.E.,Schirle Oakdale, N.S.,Braeuning, B.,Boydston, E.A.,Sevillano, N.,Popova, K.D.,Bonnar, J.L.,Shurtleff, M.J.,Prabu, J.R.,Stroud, R.M.,Craik, C.S.,Schulman, B.A.,Weissman, J.S.,Frost, A. (deposition date: 2020-11-19, release date: 2020-12-02, Last modification date: 2020-12-09)

• Primary citation: Miller-Vedam, L.E.,Brauning, B.,Popova, K.D.,Schirle Oakdale, N.T.,Bonnar, J.L.,Prabu, J.R.,Boydston, E.A.,Sevillano, N.,Shurtleff, M.J.,Stroud, R.M.,Craik, C.S.,Schulman, B.A.,Frost, A.,Weissman, J.S.; Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.; Elife, 9:-, 2020; PubMed: 33236988; DOI: 10.7554/eLife.62611

Experimental method

ELECTRON MICROSCOPY (3.2 Å)