8CDV
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![BU of 8cdv by Molmil](/molmil-images/mine/8cdv) | Rnase R bound to a 30S degradation intermediate (state II) | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | 登録日 | 2023-02-01 | 公開日 | 2023-12-20 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.73 Å) | 主引用文献 | Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
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7AZ5
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![BU of 7az5 by Molmil](/molmil-images/mine/7az5) | DNA polymerase sliding clamp from Escherichia coli with peptide 47 bound | 分子名称: | Beta sliding clamp, DI(HYDROXYETHYL)ETHER, Peptide 47, ... | 著者 | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | 登録日 | 2020-11-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
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6UZN
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6UZS
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5MQN
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![BU of 5mqn by Molmil](/molmil-images/mine/5mqn) | Glycoside hydrolase BT_0986 | 分子名称: | CALCIUM ION, Glycosyl hydrolases family 2, sugar binding domain | 著者 | Basle, A, Ndeh, D, Rogowski, A, Cartmell, A, Luis, A.S, Venditto, I, Labourel, A, Gilbert, H.J. | 登録日 | 2016-12-20 | 公開日 | 2017-03-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Complex pectin metabolism by gut bacteria reveals novel catalytic functions. Nature, 544, 2017
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7O2R
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![BU of 7o2r by Molmil](/molmil-images/mine/7o2r) | Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with ITF3985 | 分子名称: | 3,5-bis(fluoranyl)-~{N}-oxidanyl-4-[(5-pyrimidin-2-yl-1,2,3,4-tetrazol-2-yl)methyl]benzamide, DI(HYDROXYETHYL)ETHER, Histone deacetylase 6, ... | 著者 | Zrubek, K, Sandrone, G, Cukier, C.D, Stevenazzi, A. | 登録日 | 2021-03-31 | 公開日 | 2021-10-27 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Role of Fluorination in the Histone Deacetylase 6 (HDAC6) Selectivity of Benzohydroxamate-Based Inhibitors. Acs Med.Chem.Lett., 12, 2021
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7AZ8
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![BU of 7az8 by Molmil](/molmil-images/mine/7az8) | DNA polymerase sliding clamp from Escherichia coli with peptide 43 bound | 分子名称: | Beta sliding clamp, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | 登録日 | 2020-11-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
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5MU2
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![BU of 5mu2 by Molmil](/molmil-images/mine/5mu2) | ACC1 Fab fragment in complex with CII583-591 (CG10) | 分子名称: | ACC1 Fab fragment heavy chain, ACC1 Fab fragment light chain, synthetic peptide containing the CII583-591 epitope of collagen type II | 著者 | Dobritzsch, D, Holmdahl, R, Ge, C. | 登録日 | 2017-01-12 | 公開日 | 2017-07-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. JCI Insight, 2, 2017
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7AZE
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![BU of 7aze by Molmil](/molmil-images/mine/7aze) | DNA polymerase sliding clamp from Escherichia coli with peptide 18 bound | 分子名称: | Beta sliding clamp, GLYCEROL, MALONATE ION, ... | 著者 | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | 登録日 | 2020-11-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
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6SS4
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![BU of 6ss4 by Molmil](/molmil-images/mine/6ss4) | Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0021181 | 分子名称: | Arginase-2, mitochondrial, Fab C0021181 heavy chain (IgG1), ... | 著者 | Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M. | 登録日 | 2019-09-06 | 公開日 | 2020-06-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action. Mabs, 12
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8HKQ
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![BU of 8hkq by Molmil](/molmil-images/mine/8hkq) | ion channel | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | 著者 | Jiang, D.H, Zhang, J.T. | 登録日 | 2022-11-27 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8C1L
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![BU of 8c1l by Molmil](/molmil-images/mine/8c1l) | Crystal structure of HNF4 alpha LBD in complexes with palmitic acid and GRIP-1 peptide | 分子名称: | 1,2-ETHANEDIOL, Hepatocyte nuclear factor 4-alpha, Nuclear receptor coactivator 2, ... | 著者 | Ni, X, Merk, D, Zhubi, R, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-12-20 | 公開日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of HNF4 alpha LBD in complexes with palmitic acid and GRIP-1 peptide To Be Published
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8HKK
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![BU of 8hkk by Molmil](/molmil-images/mine/8hkk) | ion channel | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | 著者 | Jiang, D.H, Zhang, J.T. | 登録日 | 2022-11-27 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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6Y6B
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![BU of 6y6b by Molmil](/molmil-images/mine/6y6b) | Crystal structure of human 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser100 and 16-OMe-Fusicoccin H | 分子名称: | (2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[[(1~{S},3~{R},6~{S},7~{S},8~{R},9~{R},10~{R},11~{R},14~{S})-14-(me thoxymethyl)-3,10-dimethyl-9-oxidanyl-6-propan-2-yl-8-tricyclo[9.3.0.0^{3,7}]tetradecanyl]oxy]oxane-3,4,5-triol, 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2 | 著者 | Lentini Santo, D, Obsilova, V, Obsil, T. | 登録日 | 2020-02-26 | 公開日 | 2021-02-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | 主引用文献 | Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins. Acs Chem.Biol., 15, 2020
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7AZK
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![BU of 7azk by Molmil](/molmil-images/mine/7azk) | DNA polymerase sliding clamp from Escherichia coli with peptide 35 bound | 分子名称: | Beta sliding clamp, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | 登録日 | 2020-11-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
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8HIR
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![BU of 8hir by Molmil](/molmil-images/mine/8hir) | potassium channels | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | 著者 | Jiang, D.H, Zhang, J.T. | 登録日 | 2022-11-21 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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3ILR
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![BU of 3ilr by Molmil](/molmil-images/mine/3ilr) | Structure of Heparinase I from Bacteroides thetaiotaomicron in complex with tetrasaccharide product | 分子名称: | 1,2-ETHANEDIOL, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(4-1)-4-deoxy-2-O-sulfo-beta-D-erythro-hex-4-enopyranuronic acid, 4-deoxy-2-O-sulfo-beta-D-erythro-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ... | 著者 | Garron, M.L, Cygler, M, Shaya, D. | 登録日 | 2009-08-07 | 公開日 | 2009-09-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural snapshots of heparin depolymerization by heparin lyase I. J.Biol.Chem., 284, 2009
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6MVO
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![BU of 6mvo by Molmil](/molmil-images/mine/6mvo) | HCV NS5B 1A Y316 bound to Compound 49 | 分子名称: | 6-[(7-chloro-1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)(methylsulfonyl)amino]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide, RNA-directed RNA polymerase, SULFATE ION | 著者 | Williams, S.P, Kahler, K, Price, D.J, Peat, A.J. | 登録日 | 2018-10-26 | 公開日 | 2019-09-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Design of N-Benzoxaborole Benzofuran GSK8175-Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor. J.Med.Chem., 62, 2019
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8HKM
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![BU of 8hkm by Molmil](/molmil-images/mine/8hkm) | ion channel | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION, ... | 著者 | Jiang, D.H, Zhang, J.T. | 登録日 | 2022-11-27 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HK6
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![BU of 8hk6 by Molmil](/molmil-images/mine/8hk6) | potassium channel | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION | 著者 | Jiang, D.H, Zhang, J.T. | 登録日 | 2022-11-25 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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6Y8S
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![BU of 6y8s by Molmil](/molmil-images/mine/6y8s) | Crystal structure of the quaternary ammonium Rieske monooxygenase CntA in complex with substrate gamma-butyrobetaine | 分子名称: | 3-CARBOXY-N,N,N-TRIMETHYLPROPAN-1-AMINIUM, Carnitine monooxygenase oxygenase subunit, FE (III) ION, ... | 著者 | Quareshy, M, Shanmugam, M, Bugg, T.D, Cameron, A, Chen, Y. | 登録日 | 2020-03-05 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.629 Å) | 主引用文献 | Structural basis of carnitine monooxygenase CntA substrate specificity, inhibition, and intersubunit electron transfer. J.Biol.Chem., 296, 2020
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6MVP
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![BU of 6mvp by Molmil](/molmil-images/mine/6mvp) | HCV NS5B 1b N316 bound to Compound 18 | 分子名称: | (4-{[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl](methylsulfonyl)amino}phenyl)boronic acid, Genome polyprotein | 著者 | Williams, S.P, Kahler, K, Price, D.J, Peat, A.J. | 登録日 | 2018-10-26 | 公開日 | 2019-09-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Design of N-Benzoxaborole Benzofuran GSK8175-Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor. J.Med.Chem., 62, 2019
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7TFS
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![BU of 7tfs by Molmil](/molmil-images/mine/7tfs) | Cryo-EM of the OmcE nanowires from Geobacter sulfurreducens | 分子名称: | Cytochrome c, HEME C | 著者 | Wang, F, Mustafa, K, Chan, C.H, Joshi, K, Hochbaum, A.I, Bond, D.R, Egelman, E.H. | 登録日 | 2022-01-07 | 公開日 | 2022-05-04 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Cryo-EM structure of an extracellular Geobacter OmcE cytochrome filament reveals tetrahaem packing. Nat Microbiol, 7, 2022
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8HKF
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![BU of 8hkf by Molmil](/molmil-images/mine/8hkf) | ion channel | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION | 著者 | Jiang, D.H, Zhang, Z.T. | 登録日 | 2022-11-25 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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6BHY
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