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PDB: 53012 件

8XIY
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Crystal structure of an omega-transaminase mutant I77L/Q97E/H210N/N245D from Aspergillus terreus in complex with PLP
分子名称: D-aminoacid aminotransferase-like PLP-dependent enzyme, PYRIDOXAL-5'-PHOSPHATE
著者Lu, Z.Y, Hu, D, Xu, D.Z, He, Y.C.
登録日2023-12-20
公開日2024-02-07
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Efficient bioamination with an omega-transaminase mutant from Aspergillus terreus
To Be Published
8XIZ
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Crystal structure of an epoxide hydrolase mutant A250IC/L344V from Aspergillus usamii E001 at 2.17 Angstroms resolution
分子名称: Microsomal epoxide hyddrolase
著者Hu, B.C, Lu, Z.Y, Tang, C.D, Hu, D.
登録日2023-12-20
公開日2024-02-07
実験手法X-RAY DIFFRACTION (2.175 Å)
主引用文献Directed evolution of an epoxide hydrolase and its structural mechanism for the enantioselectivity improvement toward chiral ortho-fluorostyrene oxide
To Be Published
9G0B
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Rhinovirus A2 uncoating intermediate revealing the natural pocket factor (pH 5.8 and 4 degrees Celsius)
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Real-Hohn, A, Blaas, D.
登録日2024-07-07
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Rhinovirus A2 uncoating intermediate revealing the natural pocket factor (pH 5.8 and 4 degrees Celsius)
To Be Published
8XMI
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Potassium transporter KtrAB from Bacillus subtilis in ATP-bound state with addition of EDTA and EGTA, C1 symmetry
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ...
著者Chang, Y.K, Chiang, W.T, Hu, N.J, Tsai, M.D.
登録日2023-12-27
公開日2024-04-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB.
Nat Commun, 15, 2024
8UC8
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HCN1 nanodisc
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
著者Kim, E.D, Nimigean, C.M.
登録日2023-09-25
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants
Nature, 2024
8XOB
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VMAT2 protonated state
分子名称: Synaptic vesicular amine transporter,transporter B
著者Jiang, D.H, Wu, D.
登録日2023-12-31
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献VMAT2 protonated state
To Be Published
8WT1
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Crystal structure of S9 carboxypeptidase from Geobacillus sterothermophilus
分子名称: ALANINE, CITRATE ANION, GLYCEROL, ...
著者Chandravanshi, K, Kumar, A, Sen, C, Singh, R, Bhange, G.B, Makde, R.D.
登録日2023-10-17
公開日2024-03-13
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure and solution scattering of Geobacillus stearothermophilus S9 peptidase reveal structural adaptations for carboxypeptidase activity.
Febs Lett., 598, 2024
8XMH
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Potassium transporter KtrAB from Bacillus subtilis in ATP-bound state with addition of EDTA and EGTA, vertical C2 symmetry axis
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ...
著者Chang, Y.K, Chiang, W.T, Hu, N.J, Tsai, M.D.
登録日2023-12-27
公開日2024-04-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB.
Nat Commun, 15, 2024
8Y7G
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Crystal structure of the Marinitoga sp. Csx1-Crn2 H495A mutant in complex with cyclic-tetraadenylate (cA4)
分子名称: ACETATE ION, CRISPR-associated protein, RNA (5'-R(P*AP*A)-3'), ...
著者Zhang, D, Yuan, C, Lin, Z.
登録日2024-02-04
公開日2024-07-17
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system.
Nucleic Acids Res., 2024
7OV2
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Crystal structure of pig purple acid phosphatase in complex with L-glutamine, (poly)ethylene glycol fragments and glycerol
分子名称: 1,2-ETHANEDIOL, CITRIC ACID, FE (III) ION, ...
著者Feder, D, McGeary, R.P, Guddat, L.W, Schenk, G.
登録日2021-06-14
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Rational Design of Potent Inhibitors of a Metallohydrolase Using a Fragment-Based Approach.
Chemmedchem, 16, 2021
8XO9
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VMAT2 complex with noradrenaline in cytosol-facing state
分子名称: Noradrenaline, Synaptic vesicular amine transporter,Synaptic vesicular amine transporter,transporter A
著者Jiang, D.H, Wu, D.
登録日2023-12-31
公開日2024-05-08
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献VMAT2 complex with noradrenaline in cytosol-facing state
To Be Published
8VYL
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The structure of Human Hemoglobin in Complex with Nanobody BtNbE11
分子名称: ACETYL GROUP, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
著者Grinter, R, Binks, S, Fox, D.
登録日2024-02-08
公開日2024-07-17
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献The structure of a haemoglobin-nanobody complex reveals human beta-subunit-specific interactions.
Febs Lett., 2024
9C5S
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BU of 9c5s by Molmil
Disulfide-linked, antiparallel p53-derived peptide dimer (CV1)
分子名称: Cellular tumor antigen p53, SULFATE ION
著者Vithanage, N, Kreitler, D.K, DiGiorno, M.C, Victorio, C.G, Sawyer, N, Outlaw, V.K.
登録日2024-06-06
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.01 Å)
主引用文献Structural Characterization of Disulfide-Linked, p53-Derived Peptide Dimers
To Be Published
7P6S
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Crystal structure of the FimH-binding decoy module of human glycoprotein 2 (GP2) (crystal form II)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform Alpha of Pancreatic secretory granule membrane major glycoprotein GP2, pentane-1,5-diol
著者Stsiapanava, A, Tunyasuvunakool, K, Jumper, J, de Sanctis, D, Jovine, L.
登録日2021-07-17
公開日2022-03-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
7P6T
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Crystal structure of the FimH-binding decoy module of human glycoprotein 2 (GP2) (crystal form III)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-ethyl-2-(hydroxymethyl)propane-1,3-diol, Isoform Alpha of Pancreatic secretory granule membrane major glycoprotein GP2
著者Stsiapanava, A, Tunyasuvunakool, K, Jumper, J, de Sanctis, D, Jovine, L.
登録日2021-07-17
公開日2022-03-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
7P6R
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Crystal structure of the FimH-binding decoy module of human glycoprotein 2 (GP2) (crystal form I)
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform Alpha of Pancreatic secretory granule membrane major glycoprotein GP2
著者Stsiapanava, A, Tunyasuvunakool, K, Jumper, J, de Sanctis, D, Jovine, L.
登録日2021-07-17
公開日2022-03-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
9ARD
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BU of 9ard by Molmil
Structure of Pycsar EcPycC cyclase immunoglobulin-like AGS-C domain
分子名称: Cytidylate cyclase
著者Richmond-Buccola, D, Kranzusch, P.J.
登録日2024-02-23
公開日2024-06-19
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献A large-scale type I CBASS antiphage screen identifies the phage prohead protease as a key determinant of immune activation and evasion.
Cell Host Microbe, 32, 2024
7OOF
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BU of 7oof by Molmil
Crystal structure of Paradendryphiella salina PL7A alginate lyase in complex with tri-mannuronic acid
分子名称: Alginate lyase (PL7), TETRAETHYLENE GLYCOL, alpha-D-mannopyranuronic acid, ...
著者Fredslund, F, Welner, D.H, Wilkens, C.
登録日2021-05-27
公開日2022-06-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of Paradendryphiella salina PL7A alginate lyase in complex with tri-mannuronic acid
To Be Published
8BRN
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BU of 8brn by Molmil
Crystal structure of red kidney bean purple acid phosphatase in complex with an alpha-aminonaphthylmethylphosphonic acid inhibitor
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Feder, D, Hussein, W.M, Guddat, L.W, Schenk, G.
登録日2022-11-23
公開日2023-08-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Optimization of an alpha-aminonaphthylmethylphosphonic acid inhibitor of purple acid phosphatase using rational structure-based design approaches.
Eur.J.Med.Chem., 254, 2023
9B12
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Structure of Optineurin bound to HOIP NZF1 domain and M1-linked diubiquitin, crystal form 1
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, E3 ubiquitin-protein ligase RNF31, ...
著者Michel, M.A, Scutts, S, Komander, D.
登録日2024-03-12
公開日2024-07-31
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Linkage and substrate specificity conferred by NZF ubiquitin binding domains
To Be Published
8DVN
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Crystal structure of LRP6 E3E4 in complex with disulfide constrained peptide E3.10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Thakur, A.K, Liau, N.P.D, Sudhamsu, J, Hannoush, R.N.
登録日2022-07-29
公開日2023-03-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/ beta-Catenin Signaling via LRP6 Coreceptor Clustering.
Acs Chem.Biol., 18, 2023
8DVM
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Crystal structure of LRP6 E3E4 in complex with disulfide constrained peptide E3.6
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Thakur, A.K, Liau, N.P.D, Sudhamsu, J, Hannoush, R.N.
登録日2022-07-29
公開日2023-03-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/ beta-Catenin Signaling via LRP6 Coreceptor Clustering.
Acs Chem.Biol., 18, 2023
8DVL
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Crystal structure of LRP6 E3E4 in complex with disulfide constrained peptide E3.18
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Thakur, A.K, Liau, N.P.D, Sudhamsu, J, Hannoush, R.N.
登録日2022-07-29
公開日2023-03-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/ beta-Catenin Signaling via LRP6 Coreceptor Clustering.
Acs Chem.Biol., 18, 2023
6OJL
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Structure of YePL2A R194K in Complex with Pentagalacturonic Acid
分子名称: 1,2-ETHANEDIOL, Periplasmic pectate lyase, alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-beta-D-galactopyranuronic acid
著者Jones, D.R, Abbott, D.W.
登録日2019-04-11
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A surrogate structural platform informed by ancestral reconstruction and resurrection of a putative carbohydrate binding module hybrid illuminates the neofunctionalization of a pectate lyase.
J.Struct.Biol., 207, 2019
173L
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PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
分子名称: BETA-MERCAPTOETHANOL, T4 LYSOZYME
著者Xiong, X.-P, Zhang, X.-J, Sun, D, Matthews, B.W.
登録日1995-03-24
公開日1995-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995

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件を2024-07-31に公開中

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