9B12

Structure of Optineurin bound to HOIP NZF1 domain and M1-linked diubiquitin, crystal form 1

Summary for 9B12

Entry DOI	10.2210/pdb9b12/pdb
Descriptor	Optineurin, Ubiquitin, E3 ubiquitin-protein ligase RNF31, ... (9 entities in total)
Functional Keywords	optineurin, autophagy, mitophagy, xenophagy, uban, nzf, hoip, lubac, linear ub chain, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	10
Total formula weight	93468.35
Authors	Michel, M.A.,Scutts, S.,Komander, D. (deposition date: 2024-03-12, release date: 2024-07-31)
Primary citation	Michel, M.A.,Scutts, S.,Komander, D. Linkage and substrate specificity conferred by NZF ubiquitin binding domains To Be Published,
Experimental method	X-RAY DIFFRACTION (1.81 Å)

Structure validation