9B12
Structure of Optineurin bound to HOIP NZF1 domain and M1-linked diubiquitin, crystal form 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | C, D, E, F | Optineurin | polymer | 96 | 11017.5 | 4 | UniProt (Q96CV9) In PDB | Homo sapiens (human) | E3-14.7K-interacting protein,FIP-2,Huntingtin yeast partner L,Huntingtin-interacting protein 7,HIP-7,Huntingtin-interacting protein L,NEMO-related protein,Optic neuropathy-inducing protein,Transcription factor IIIA-interacting protein,TFIIIA-IntP |
| 2 | A, B | Ubiquitin | polymer | 152 | 17135.7 | 2 | UniProt (P0CG47) In PDB | Homo sapiens (human) | |
| 3 | G, H, I, J | E3 ubiquitin-protein ligase RNF31 | polymer | 30 | 3316.8 | 4 | UniProt (Q96EP0) In PDB | Homo sapiens (human) | HOIL-1-interacting protein,HOIP,RING finger protein 31,RING-type E3 ubiquitin transferase RNF31,Zinc in-between-RING-finger ubiquitin-associated domain protein |
| 4 | C, J | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 5 | C | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 6 | F, B, J | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 7 | F, A, H, J | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 4 | Chemie (EPE) | |||
| 8 | G, H, I, J | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 9 | water | water | 18.0 | 187 | Chemie (HOH) |
Sequence modifications
C, D, E, F: 419 - 512 (UniProt: Q96CV9)
| PDB | External Database | Details |
|---|---|---|
| Gly 417 | - | expression tag |
| Pro 418 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 91608.5 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1859.8 | |
| All* | Total formula weight | 93468.4 |
