8BRN
Crystal structure of red kidney bean purple acid phosphatase in complex with an alpha-aminonaphthylmethylphosphonic acid inhibitor
Summary for 8BRN
| Entry DOI | 10.2210/pdb8brn/pdb |
| Descriptor | Fe(3+)-Zn(2+) purple acid phosphatase, alpha-L-fucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (23 entities in total) |
| Functional Keywords | metallohydrolase, phosphatase, metal binding protein |
| Biological source | Phaseolus vulgaris |
| Total number of polymer chains | 4 |
| Total formula weight | 226076.82 |
| Authors | Feder, D.,Hussein, W.M.,Guddat, L.W.,Schenk, G. (deposition date: 2022-11-23, release date: 2023-08-02) |
| Primary citation | Feder, D.,Mohd-Pahmi, S.H.,Adibi, H.,Guddat, L.W.,Schenk, G.,McGeary, R.P.,Hussein, W.M. Optimization of an alpha-aminonaphthylmethylphosphonic acid inhibitor of purple acid phosphatase using rational structure-based design approaches. Eur.J.Med.Chem., 254:115383-115383, 2023 Cited by PubMed: 37087894DOI: 10.1016/j.ejmech.2023.115383 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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