7OV2
Crystal structure of pig purple acid phosphatase in complex with L-glutamine, (poly)ethylene glycol fragments and glycerol
Summary for 7OV2
| Entry DOI | 10.2210/pdb7ov2/pdb |
| Related | 6VKB |
| Descriptor | Tartrate-resistant acid phosphatase type 5, GLYCEROL, CITRIC ACID, ... (14 entities in total) |
| Functional Keywords | purple acid phosphatase, metallohydrolases, osteoporosis, fragment-based drug design, metal binding protein, hydrolase |
| Biological source | Sus scrofa (Pig) |
| Total number of polymer chains | 1 |
| Total formula weight | 45017.66 |
| Authors | Feder, D.,McGeary, R.P.,Guddat, L.W.,Schenk, G. (deposition date: 2021-06-14, release date: 2022-01-12, Last modification date: 2024-01-31) |
| Primary citation | Feder, D.,Mohd-Pahmi, S.H.,Hussein, W.M.,Guddat, L.W.,McGeary, R.P.,Schenk, G. Rational Design of Potent Inhibitors of a Metallohydrolase Using a Fragment-Based Approach. Chemmedchem, 16:3342-3359, 2021 Cited by PubMed: 34331400DOI: 10.1002/cmdc.202100486 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report
