1JR9
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![BU of 1jr9 by Molmil](/molmil-images/mine/1jr9) | Crystal Structure of manganese superoxide dismutases from Bacillus halodenitrificans | Descriptor: | MANGANESE (II) ION, ZINC ION, manganese superoxide dismutase | Authors: | Liao, J, Liu, M.Y, Chang, T, Li, M, LeGall, J, Gui, L.L, Zhang, J.P, Jiang, T, Liang, D.C, Chang, W.R. | Deposit date: | 2001-08-13 | Release date: | 2002-08-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Three-dimensional structure of manganese superoxide dismutase from Bacillus halodenitrificans, a component of the so-called "green protein". J.Struct.Biol., 139, 2002
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5K2C
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![BU of 5k2c by Molmil](/molmil-images/mine/5k2c) | 1.9 angstrom A2a adenosine receptor structure with sulfur SAD phasing and phase extension using XFEL data | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a/Soluble cytochrome b562 chimera, ... | Authors: | Batyuk, A, Galli, L, Ishchenko, A, Han, G.W, Gati, C, Popov, P, Lee, M.-Y, Stauch, B, White, T.A, Barty, A, Aquila, A, Hunter, M.S, Liang, M, Boutet, S, Pu, M, Liu, Z.-J, Nelson, G, James, D, Li, C, Zhao, Y, Spence, J.C.H, Liu, W, Fromme, P, Katritch, V, Weierstall, U, Stevens, R.C, Cherezov, V, GPCR Network (GPCR) | Deposit date: | 2016-05-18 | Release date: | 2016-09-21 | Last modified: | 2018-11-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Native phasing of x-ray free-electron laser data for a G protein-coupled receptor. Sci Adv, 2, 2016
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4R1P
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3EE8
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4IKN
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![BU of 4ikn by Molmil](/molmil-images/mine/4ikn) | Crystal structure of adaptor protein complex 3 (AP-3) mu3A subunit C-terminal domain, in complex with a sorting peptide from TGN38 | Descriptor: | AP-3 complex subunit mu-1, Trans-Golgi network integral membrane protein TGN38 | Authors: | Mardones, G.A, Kloer, D.P, Burgos, P.V, Bonifacino, J.S, Hurley, J.H. | Deposit date: | 2012-12-26 | Release date: | 2013-02-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.851 Å) | Cite: | Structural basis for the recognition of tyrosine-based sorting signals by the mu 3A subunit of the AP-3 adaptor complex. J.Biol.Chem., 288, 2013
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5K8S
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![BU of 5k8s by Molmil](/molmil-images/mine/5k8s) | cAMP bound PfPKA-R (297-441) | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP-dependent protein kinase regulatory subunit | Authors: | Littler, D.R, Gilson, P.R, Crabb, B.S, Rossjohn, J.J. | Deposit date: | 2016-05-31 | Release date: | 2016-10-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit. J. Biol. Chem., 291, 2016
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6P9B
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7T0O
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6P9A
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![BU of 6p9a by Molmil](/molmil-images/mine/6p9a) | HIV-1 Protease multiple mutant PRS5B with Darunavir | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, HIV-1 Protease, PHOSPHATE ION | Authors: | Kneller, D.W, Agniswamy, J, Weber, I.T. | Deposit date: | 2019-06-10 | Release date: | 2020-04-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Highly drug-resistant HIV-1 protease reveals decreased intra-subunit interactions due to clusters of mutations. Febs J., 287, 2020
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5KDO
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![BU of 5kdo by Molmil](/molmil-images/mine/5kdo) | Heterotrimeric complex of the 4 alanine insertion variant of the Gi alpha1 subunit and the Gbeta1-Ggamma1 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... | Authors: | Kaya, A.I, Lokits, A.D, Gilbert, J, Iverson, T.M, Meiler, J, Hamm, H.E. | Deposit date: | 2016-06-08 | Release date: | 2016-08-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Conserved Hydrophobic Core in G alpha i1 Regulates G Protein Activation and Release from Activated Receptor. J.Biol.Chem., 291, 2016
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5JUN
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![BU of 5jun by Molmil](/molmil-images/mine/5jun) | PB2 bound to an azaindole inhibitor | Descriptor: | (3~{R})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]-3-(1-methylcyclobutyl)propanoic acid, Polymerase basic protein 2 | Authors: | Jacobs, M.D. | Deposit date: | 2016-05-10 | Release date: | 2017-05-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Discovery of Novel, Orally Bioavailable beta-Amino Acid Azaindole Inhibitors of Influenza PB2. ACS Med Chem Lett, 8, 2017
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1TF9
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![BU of 1tf9 by Molmil](/molmil-images/mine/1tf9) | Streptomyces griseus aminopeptidase complexed with P-Iodo-L-Phenylalanine | Descriptor: | Aminopeptidase, CALCIUM ION, IODO-PHENYLALANINE, ... | Authors: | Reiland, V, Gilboa, R, Spungin-Bialik, A, Schomburg, D, Shoham, Y, Blumberg, S, Shoham, G. | Deposit date: | 2004-05-27 | Release date: | 2005-05-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Binding of inhibitory aromatic amino acids to Streptomyces griseus aminopeptidase. Acta Crystallogr.,Sect.D, 60, 2004
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6VSI
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![BU of 6vsi by Molmil](/molmil-images/mine/6vsi) | Crystal structure of FKBP12 of Candida auris | Descriptor: | Peptidylprolyl isomerase, SULFATE ION | Authors: | Li, Z, Li, H, Hernandez, G, LeMaster, D. | Deposit date: | 2020-02-11 | Release date: | 2020-04-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Crystal structure and transient dimerization for the FKBP12 protein from the pathogenic fungus Candida auris. Biochem.Biophys.Res.Commun., 525, 2020
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1THF
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1THL
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![BU of 1thl by Molmil](/molmil-images/mine/1thl) | Thermolysin complexed with a novel glutaramide derivative, n-(1-(2(r,s)-carboxy-4-phenylbutyl) cyclopentylcarbonyl)-(s)-tryptophan | Descriptor: | CALCIUM ION, N-({1-[(2S)-2-carboxy-4-phenylbutyl]cyclopentyl}carbonyl)-L-tryptophan, THERMOLYSIN, ... | Authors: | Holland, D.R, Matthews, B.W. | Deposit date: | 1993-11-17 | Release date: | 1994-01-31 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Inhibition of Thermolysin and Neutral Endopeptidase 24.11 By a Novel Glutaramide Derivative; X-Ray Structure Determination of the Thermolysin-Inhibitor Complex Biochemistry, 33, 1994
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6IKM
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![BU of 6ikm by Molmil](/molmil-images/mine/6ikm) | Crystal structure of SpuE-Spermidine in complex with ScFv5 | Descriptor: | Polyamine transport protein, SPERMIDINE, SULFATE ION, ... | Authors: | Wu, D, Sun, X. | Deposit date: | 2018-10-16 | Release date: | 2019-12-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.398 Å) | Cite: | A Potent Anti-SpuE Antibody Allosterically Inhibits Type III Secretion System and Attenuates Virulence of Pseudomonas Aeruginosa. J.Mol.Biol., 431, 2019
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6W3J
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![BU of 6w3j by Molmil](/molmil-images/mine/6w3j) | Crystal structure of the FAM46C/Plk4/Cep192 complex | Descriptor: | Centrosomal protein of 192 kDa, Serine/threonine-protein kinase PLK4, Terminal nucleotidyltransferase 5C | Authors: | Chen, H, Lu, D.F, Shang, G.J, Zhang, X.W. | Deposit date: | 2020-03-09 | Release date: | 2020-05-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (4.385 Å) | Cite: | Structural and Functional Analyses of the FAM46C/Plk4 Complex. Structure, 28, 2020
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6PIM
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![BU of 6pim by Molmil](/molmil-images/mine/6pim) | Crystal Structure of Human Protocadherin-1 EC3-4 | Descriptor: | CALCIUM ION, Protocadherin-1 | Authors: | Modak, D, Sotomayor, M. | Deposit date: | 2019-06-26 | Release date: | 2019-10-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Identification of an adhesive interface for the non-clustered delta 1 protocadherin-1 involved in respiratory diseases. Commun Biol, 2, 2019
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3EAY
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![BU of 3eay by Molmil](/molmil-images/mine/3eay) | Crystal structure of the human SENP7 catalytic domain | Descriptor: | SULFATE ION, Sentrin-specific protease 7 | Authors: | Lima, C.D, Reverter, D. | Deposit date: | 2008-08-26 | Release date: | 2008-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the Human SENP7 Catalytic Domain and Poly-SUMO Deconjugation Activities for SENP6 and SENP7. J.Biol.Chem., 283, 2008
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5K3J
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![BU of 5k3j by Molmil](/molmil-images/mine/5k3j) | Crystals structure of Acyl-CoA oxidase-2 in Caenorhabditis elegans bound with FAD, ascaroside-CoA, and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Acyl-coenzyme A oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A. | Deposit date: | 2016-05-19 | Release date: | 2016-08-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans. Proc.Natl.Acad.Sci.USA, 113, 2016
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2HGF
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![BU of 2hgf by Molmil](/molmil-images/mine/2hgf) | HAIRPIN LOOP CONTAINING DOMAIN OF HEPATOCYTE GROWTH FACTOR, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | HEPATOCYTE GROWTH FACTOR | Authors: | Zhou, H, Mazzulla, M.J, Kaufman, J.D, Stahl, S.J, Wingfield, P.T, Rubin, J.S, Bottaro, D.P, Byrd, R.A. | Deposit date: | 1997-12-18 | Release date: | 1998-06-24 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | The solution structure of the N-terminal domain of hepatocyte growth factor reveals a potential heparin-binding site. Structure, 6, 1998
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4IJ3
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3EHH
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5K2A
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![BU of 5k2a by Molmil](/molmil-images/mine/5k2a) | 2.5 angstrom A2a adenosine receptor structure with sulfur SAD phasing using XFEL data | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a/Soluble cytochrome b562 chimera, ... | Authors: | Batyuk, A, Galli, L, Ishchenko, A, Han, G.W, Gati, C, Popov, P, Lee, M.-Y, Stauch, B, White, T.A, Barty, A, Aquila, A, Hunter, M.S, Liang, M, Boutet, S, Pu, M, Liu, Z.-J, Nelson, G, James, D, Li, C, Zhao, Y, Spence, J.C.H, Liu, W, Fromme, P, Katritch, V, Weierstall, U, Stevens, R.C, Cherezov, V, GPCR Network (GPCR) | Deposit date: | 2016-05-18 | Release date: | 2016-09-21 | Last modified: | 2018-11-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Native phasing of x-ray free-electron laser data for a G protein-coupled receptor. Sci Adv, 2, 2016
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6PDP
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![BU of 6pdp by Molmil](/molmil-images/mine/6pdp) | Human PIM1 bound to benzothiophene inhibitor 379 | Descriptor: | 5-[2-(acetylamino)-1-benzothiophen-4-yl]-N-cyclopropylthiophene-2-carboxamide, Peptide, SULFATE ION, ... | Authors: | Godoi, P.H.C, Sriranganadane, D, Santiago, A.S, Fala, A.M, Ramos, P.Z, Mascarello, A, Segretti, N, Azevedo, H, Guimaraes, C.R.W, Arruda, P, Elkins, J.M, Counago, R.M, Structural Genomics Consortium (SGC) | Deposit date: | 2019-06-19 | Release date: | 2019-07-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Human PIM1 To Be Published
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