5KDO

Heterotrimeric complex of the 4 alanine insertion variant of the Gi alpha1 subunit and the Gbeta1-Ggamma1

Summary for 5KDO

Entry DOI	10.2210/pdb5kdo/pdb
Related	5KDL
Descriptor	Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... (5 entities in total)
Functional Keywords	heterotrimeric g protein g protein coupled receptors g protein activation g protein structure gdp release, signaling protein
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	3
Total formula weight	87100.40
Authors	Kaya, A.I.,Lokits, A.D.,Gilbert, J.,Iverson, T.M.,Meiler, J.,Hamm, H.E. (deposition date: 2016-06-08, release date: 2016-08-03, Last modification date: 2023-09-27)
Primary citation	Kaya, A.I.,Lokits, A.D.,Gilbert, J.A.,Iverson, T.M.,Meiler, J.,Hamm, H.E. A Conserved Hydrophobic Core in G alpha i1 Regulates G Protein Activation and Release from Activated Receptor. J.Biol.Chem., 291:19674-19686, 2016 Cited by PubMed: 27462082 DOI: 10.1074/jbc.M116.745513 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation