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PDB: 45 results
8DBZ
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BU of 8dbz by Molmil
CryoEM structure of Hantavirus ANDV Gn(H) protein complex with 2Fabs ANDV-5 and ANDV-34
Descriptor: COV44-79 heavy chain constant domain, Fab Fc (L) KappaC, Fv (H) ANDV-34, ...
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2022-06-15
Release date:2023-04-05
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Antigenic mapping and functional characterization of human new world hantavirus neutralizing antibodies.
Elife, 12, 2023
8EKD
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BU of 8ekd by Molmil
Cryo-EM map of SARS-CoV-2 Omicron BA.2 spike in complex with 2130-1-0114-112
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab LLNL-199 HC, Fab LLNL-199 LC, ...
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2022-09-20
Release date:2024-02-21
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Computationally restoring the potency of a clinical antibody against Omicron.
Nature, 629, 2024
7L7E
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BU of 7l7e by Molmil
Crystal structure of SARS-CoV-2 spike RBD in complex with human monoclonal antibodies AZD8895 and AZD1061
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, Spike protein S1, ...
Authors:Dong, J, Crowe, J.E.
Deposit date:2020-12-28
Release date:2021-09-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail.
Nat Microbiol, 6, 2021
7L7D
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BU of 7l7d by Molmil
Crystal structure of SARS-CoV-2 spike RBD in complex with human monoclonal antibody AZD8895
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Spike protein S1, ...
Authors:Dong, J, Crowe, J.E.
Deposit date:2020-12-28
Release date:2021-09-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail.
Nat Microbiol, 6, 2021
6OZ9
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BU of 6oz9 by Molmil
Ebola virus glycoprotein in complex with EBOV-520 Fab
Descriptor: EBOV-520 Fab heavy chain, EBOV-520 Fab light chain, Envelope glycoprotein, ...
Authors:Milligan, J.C, Altman, P.X, Hui, S, Hastie, K.M, Gilchuk, P, Crowe, J.E, Saphire, E.O.
Deposit date:2019-05-15
Release date:2020-03-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.462 Å)
Cite:Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Immunity, 52, 2020
6P9J
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BU of 6p9j by Molmil
crystal structure of human anti staphylococcus aureus antibody STAU-229 Fab
Descriptor: TRIS(HYDROXYETHYL)AMINOMETHANE, human anti staphylococcus aureus antibody STAU-229 Fab heavy chain, human anti staphylococcus aureus antibody STAU-229 Fab light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2019-06-10
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.
Mbio, 10, 2019
6P9I
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BU of 6p9i by Molmil
crystal structure of human anti staphylococcus aureus antibody STAU-399 Fab
Descriptor: human anti staphylococcus aureus antibody STAU-399 Fab heavy chain, human anti staphylococcus aureus antibody STAU-399 Fab light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2019-06-10
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.
Mbio, 10, 2019
6P9H
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BU of 6p9h by Molmil
Crystal structure of human anti staphylococcus aureus antibody STAU-281 Fab in complex with IsdB NEAT2 domain
Descriptor: Human anti staphylococcus aureus antibody STAU-281 Fab heavy chain, Human anti staphylococcus aureus antibody STAU-281 Fab light chain, Iron-regulated heme-iron binding protein
Authors:Dong, J, Crowe, J.E.
Deposit date:2019-06-10
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.
Mbio, 10, 2019
5CGY
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BU of 5cgy by Molmil
Fab fragment of Chikungunya virus neutralizing human monoclonal antibody 4J21
Descriptor: Heavy Chain of Fab, Light Chain of Fab
Authors:Long, F, Crowe, J.E, Rossmann, M.G.
Deposit date:2015-07-09
Release date:2015-11-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.
Proc.Natl.Acad.Sci.USA, 112, 2015
5CHN
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BU of 5chn by Molmil
Fab fragments of chikungunya virus neutralizing human monoclonal antibody 5M16
Descriptor: Antibody 5M16 Fab Heavy Chain, Antibody 5M16 Fab Light Chain
Authors:Long, F, Crowe, J.E, Rossmann, M.G.
Deposit date:2015-07-10
Release date:2015-11-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.
Proc.Natl.Acad.Sci.USA, 112, 2015
5UQY
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BU of 5uqy by Molmil
Crystal structure of Marburg virus GP in complex with the human survivor antibody MR78
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN GP1, ...
Authors:Hashiguchi, T, Fusco, M.L, Hastie, K.M, Bomholdt, Z.A, Lee, J.E, Flyak, A.I, Matsuoka, R, Kohda, D, Yanagi, Y, Hammel, M, Crowe, J.E, Saphire, E.O.
Deposit date:2017-02-08
Release date:2017-03-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for Marburg virus neutralization by a cross-reactive human antibody.
Cell, 160, 2015
6DLB
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BU of 6dlb by Molmil
Crystal Structure of an influenza A hemagglutinin antibody Fab CH65:1203d4 chimera
Descriptor: CH65:1203d4 Fab heavy chain, CH65:1203d4 Fab light chain, SULFATE ION
Authors:Dong, J, Finn, J.A, Crowe, J.E.
Deposit date:2018-05-31
Release date:2019-06-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring.
Structure, 28, 2020
6DLA
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BU of 6dla by Molmil
Crystal structures of an influenza A hemagglutinin antibody Fab CH65:7969d2
Descriptor: CH65:7969d2 Fab heavy chain, CH65:7969d2 Fab light chain, SULFATE ION
Authors:Dong, J, Crowe, J.E, Finn, J.A.
Deposit date:2018-05-31
Release date:2019-06-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring.
Structure, 28, 2020
6DL8
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BU of 6dl8 by Molmil
Crystal Structure of an influenza A hemagglutinin antibody Fab variant CH67:1203d4 chimera
Descriptor: CH67:1203d4 FAB light chain, Ch67:1203d4 FAB heavy chain
Authors:Dong, J, Finn, J.A, Crowe, J.E.
Deposit date:2018-05-31
Release date:2019-06-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.805 Å)
Cite:Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring.
Structure, 28, 2020
6P3S
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BU of 6p3s by Molmil
Crystal structure of human Fab H5.28 in complex with influenza A H5N1 Vietnam hemagglutinin head domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Human Fab H5.28 heavy chain, ...
Authors:Dong, J, Crowe, J.E.
Deposit date:2019-05-24
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4 Å)
Cite:crystal structure of human Fab H5.28 in complex with influenza A H5N1 Vietnam hemagglutinin head domain
To Be Published
6P3R
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BU of 6p3r by Molmil
crystal structure of human Fab H5.31 in complex with influenza A H5N1 Vietnam hemagglutinin head domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Dong, J, Crowe, J.E.
Deposit date:2019-05-24
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of human Fab H5.31 in complex with influenza A H5N1 Vietnam hemagglutinin head domain
To Be Published
6CHX
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BU of 6chx by Molmil
High Resolution Crystal Structure of the Hemagglutinin H1 Head Domain of Influenza A virus Solomon Islands
Descriptor: Hemagglutinin
Authors:Dong, J, Sevy, A.M, Crowe, J.E.
Deposit date:2018-02-23
Release date:2019-02-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:High Resolution Crystal Structure of the Hemagglutinin H1 Head Domain of Influenza A virus Solomon Islands
To Be Published
5TPN
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BU of 5tpn by Molmil
Crystal structure of RSV F in complex with human antibody hRSV90
Descriptor: Fusion glycoprotein F0,Fibritin, hRSV0 light chain, hRSV90 heavy chain
Authors:Mousa, J.J, Crowe, J.E.
Deposit date:2016-10-20
Release date:2017-02-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.141 Å)
Cite:Crystal structure of RSV F in complex with human antibody hRSV90
To Be Published
5ANY
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BU of 5any by Molmil
Electron cryo-microscopy of chikungunya virus in complex with neutralizing antibody Fab CHK265
Descriptor: E1, E2, FAB, ...
Authors:Fox, J.M, Long, F, Edeling, M.A, Lin, H, Duijl-Richter, M, Fong, R.H, Kahle, K.M, Smit, J.M, Jin, J, Simmons, G, Doranz, B.J, Crowe, J.E, Fremont, D.H, Rossmann, M.G, Diamond, M.S.
Deposit date:2015-09-08
Release date:2015-11-25
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (16.9 Å)
Cite:Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.
Cell(Cambridge,Mass.), 163, 2015
6BP2
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BU of 6bp2 by Molmil
Therapeutic human monoclonal antibody MR191 bound to a marburgvirus glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, Envelope glycoprotein GP2, ...
Authors:King, L.B, Fusco, M.L, Flyak, A.I, Ilinykh, P.A, Huang, K, Gunn, B, Kirchdoerfer, R.N, Hastie, K.M, Sangha, A.K, Meiler, J, Alter, G, Bukreyev, A, Crowe, J.E.J, Saphire, E.O.
Deposit date:2017-11-21
Release date:2018-01-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.172 Å)
Cite:The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding.
Cell Host Microbe, 23, 2018
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