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PDB: 45 件
8DBZ
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BU of 8dbz by Molmil
CryoEM structure of Hantavirus ANDV Gn(H) protein complex with 2Fabs ANDV-5 and ANDV-34
分子名称: COV44-79 heavy chain constant domain, Fab Fc (L) KappaC, Fv (H) ANDV-34, ...
著者Binshtein, E, Crowe, J.E.
登録日2022-06-15
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Antigenic mapping and functional characterization of human new world hantavirus neutralizing antibodies.
Elife, 12, 2023
8EKD
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BU of 8ekd by Molmil
Cryo-EM map of SARS-CoV-2 Omicron BA.2 spike in complex with 2130-1-0114-112
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab LLNL-199 HC, Fab LLNL-199 LC, ...
著者Binshtein, E, Crowe, J.E.
登録日2022-09-20
公開日2024-02-21
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Computationally restoring the potency of a clinical antibody against Omicron.
Nature, 629, 2024
7L7E
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BU of 7l7e by Molmil
Crystal structure of SARS-CoV-2 spike RBD in complex with human monoclonal antibodies AZD8895 and AZD1061
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, Spike protein S1, ...
著者Dong, J, Crowe, J.E.
登録日2020-12-28
公開日2021-09-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail.
Nat Microbiol, 6, 2021
7L7D
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Crystal structure of SARS-CoV-2 spike RBD in complex with human monoclonal antibody AZD8895
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Spike protein S1, ...
著者Dong, J, Crowe, J.E.
登録日2020-12-28
公開日2021-09-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail.
Nat Microbiol, 6, 2021
6OZ9
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BU of 6oz9 by Molmil
Ebola virus glycoprotein in complex with EBOV-520 Fab
分子名称: EBOV-520 Fab heavy chain, EBOV-520 Fab light chain, Envelope glycoprotein, ...
著者Milligan, J.C, Altman, P.X, Hui, S, Hastie, K.M, Gilchuk, P, Crowe, J.E, Saphire, E.O.
登録日2019-05-15
公開日2020-03-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.462 Å)
主引用文献Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Immunity, 52, 2020
6P9J
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BU of 6p9j by Molmil
crystal structure of human anti staphylococcus aureus antibody STAU-229 Fab
分子名称: TRIS(HYDROXYETHYL)AMINOMETHANE, human anti staphylococcus aureus antibody STAU-229 Fab heavy chain, human anti staphylococcus aureus antibody STAU-229 Fab light chain
著者Dong, J, Crowe, J.E.
登録日2019-06-10
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.
Mbio, 10, 2019
6P9I
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BU of 6p9i by Molmil
crystal structure of human anti staphylococcus aureus antibody STAU-399 Fab
分子名称: human anti staphylococcus aureus antibody STAU-399 Fab heavy chain, human anti staphylococcus aureus antibody STAU-399 Fab light chain
著者Dong, J, Crowe, J.E.
登録日2019-06-10
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.
Mbio, 10, 2019
6P9H
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Crystal structure of human anti staphylococcus aureus antibody STAU-281 Fab in complex with IsdB NEAT2 domain
分子名称: Human anti staphylococcus aureus antibody STAU-281 Fab heavy chain, Human anti staphylococcus aureus antibody STAU-281 Fab light chain, Iron-regulated heme-iron binding protein
著者Dong, J, Crowe, J.E.
登録日2019-06-10
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.
Mbio, 10, 2019
5CGY
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BU of 5cgy by Molmil
Fab fragment of Chikungunya virus neutralizing human monoclonal antibody 4J21
分子名称: Heavy Chain of Fab, Light Chain of Fab
著者Long, F, Crowe, J.E, Rossmann, M.G.
登録日2015-07-09
公開日2015-11-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.
Proc.Natl.Acad.Sci.USA, 112, 2015
5CHN
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Fab fragments of chikungunya virus neutralizing human monoclonal antibody 5M16
分子名称: Antibody 5M16 Fab Heavy Chain, Antibody 5M16 Fab Light Chain
著者Long, F, Crowe, J.E, Rossmann, M.G.
登録日2015-07-10
公開日2015-11-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.047 Å)
主引用文献Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.
Proc.Natl.Acad.Sci.USA, 112, 2015
5UQY
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Crystal structure of Marburg virus GP in complex with the human survivor antibody MR78
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN GP1, ...
著者Hashiguchi, T, Fusco, M.L, Hastie, K.M, Bomholdt, Z.A, Lee, J.E, Flyak, A.I, Matsuoka, R, Kohda, D, Yanagi, Y, Hammel, M, Crowe, J.E, Saphire, E.O.
登録日2017-02-08
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural basis for Marburg virus neutralization by a cross-reactive human antibody.
Cell, 160, 2015
6DLB
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BU of 6dlb by Molmil
Crystal Structure of an influenza A hemagglutinin antibody Fab CH65:1203d4 chimera
分子名称: CH65:1203d4 Fab heavy chain, CH65:1203d4 Fab light chain, SULFATE ION
著者Dong, J, Finn, J.A, Crowe, J.E.
登録日2018-05-31
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring.
Structure, 28, 2020
6DLA
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BU of 6dla by Molmil
Crystal structures of an influenza A hemagglutinin antibody Fab CH65:7969d2
分子名称: CH65:7969d2 Fab heavy chain, CH65:7969d2 Fab light chain, SULFATE ION
著者Dong, J, Crowe, J.E, Finn, J.A.
登録日2018-05-31
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring.
Structure, 28, 2020
6DL8
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BU of 6dl8 by Molmil
Crystal Structure of an influenza A hemagglutinin antibody Fab variant CH67:1203d4 chimera
分子名称: CH67:1203d4 FAB light chain, Ch67:1203d4 FAB heavy chain
著者Dong, J, Finn, J.A, Crowe, J.E.
登録日2018-05-31
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.805 Å)
主引用文献Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring.
Structure, 28, 2020
6P3S
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BU of 6p3s by Molmil
Crystal structure of human Fab H5.28 in complex with influenza A H5N1 Vietnam hemagglutinin head domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Human Fab H5.28 heavy chain, ...
著者Dong, J, Crowe, J.E.
登録日2019-05-24
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献crystal structure of human Fab H5.28 in complex with influenza A H5N1 Vietnam hemagglutinin head domain
To Be Published
6P3R
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BU of 6p3r by Molmil
crystal structure of human Fab H5.31 in complex with influenza A H5N1 Vietnam hemagglutinin head domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Dong, J, Crowe, J.E.
登録日2019-05-24
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of human Fab H5.31 in complex with influenza A H5N1 Vietnam hemagglutinin head domain
To Be Published
6CHX
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BU of 6chx by Molmil
High Resolution Crystal Structure of the Hemagglutinin H1 Head Domain of Influenza A virus Solomon Islands
分子名称: Hemagglutinin
著者Dong, J, Sevy, A.M, Crowe, J.E.
登録日2018-02-23
公開日2019-02-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献High Resolution Crystal Structure of the Hemagglutinin H1 Head Domain of Influenza A virus Solomon Islands
To Be Published
5TPN
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BU of 5tpn by Molmil
Crystal structure of RSV F in complex with human antibody hRSV90
分子名称: Fusion glycoprotein F0,Fibritin, hRSV0 light chain, hRSV90 heavy chain
著者Mousa, J.J, Crowe, J.E.
登録日2016-10-20
公開日2017-02-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.141 Å)
主引用文献Crystal structure of RSV F in complex with human antibody hRSV90
To Be Published
5ANY
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BU of 5any by Molmil
Electron cryo-microscopy of chikungunya virus in complex with neutralizing antibody Fab CHK265
分子名称: E1, E2, FAB, ...
著者Fox, J.M, Long, F, Edeling, M.A, Lin, H, Duijl-Richter, M, Fong, R.H, Kahle, K.M, Smit, J.M, Jin, J, Simmons, G, Doranz, B.J, Crowe, J.E, Fremont, D.H, Rossmann, M.G, Diamond, M.S.
登録日2015-09-08
公開日2015-11-25
最終更新日2018-10-03
実験手法ELECTRON MICROSCOPY (16.9 Å)
主引用文献Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.
Cell(Cambridge,Mass.), 163, 2015
6BP2
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Therapeutic human monoclonal antibody MR191 bound to a marburgvirus glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, Envelope glycoprotein GP2, ...
著者King, L.B, Fusco, M.L, Flyak, A.I, Ilinykh, P.A, Huang, K, Gunn, B, Kirchdoerfer, R.N, Hastie, K.M, Sangha, A.K, Meiler, J, Alter, G, Bukreyev, A, Crowe, J.E.J, Saphire, E.O.
登録日2017-11-21
公開日2018-01-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.172 Å)
主引用文献The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding.
Cell Host Microbe, 23, 2018
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