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PDB: 268 件

3AV0
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Crystal structure of Mre11-Rad50 bound to ATP S
分子名称: DNA double-strand break repair protein mre11, DNA double-strand break repair rad50 ATPase, GLYCEROL, ...
著者Lim, H.S, Kim, J.S, Cho, Y.
登録日2011-02-18
公開日2011-05-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of the Mre11-Rad50-ATP S Complex: Understanding the Interplay between Mre11 and Rad50
To be Published
3AUY
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BU of 3auy by Molmil
Crystal structure of Rad50 bound to ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA double-strand break repair rad50 ATPase, MAGNESIUM ION
著者Lim, H.S, Cho, Y.
登録日2011-02-18
公開日2011-05-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of the Mre11-Rad50-ATP S Complex: Understanding the Interplay between Mre11 and Rad50
To be Published
3AUZ
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Crystal structure of Mre11 with manganese
分子名称: DNA double-strand break repair protein mre11, GLYCEROL, MANGANESE (II) ION
著者Park, Y.B, Cho, Y.
登録日2011-02-18
公開日2011-05-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.206 Å)
主引用文献Crystal Structure of the Mre11-Rad50-ATP S Complex: Understanding the Interplay between Mre11 and Rad50
To be Published
3AUX
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BU of 3aux by Molmil
Crystal structure of Rad50 bound to ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA double-strand break repair rad50 ATPase, MAGNESIUM ION
著者Lim, H.S, Cho, Y.
登録日2011-02-17
公開日2011-05-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of the Mre11-Rad50-ATP S Complex:Understanding the Interplay between Mre11 and Rad50
To be Published
3B64
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BU of 3b64 by Molmil
Macrophage Migration Inhibitory Factor (MIF) From /Leishmania Major
分子名称: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor-like protein
著者Zierow, S, Cho, Y, Lolis, E.
登録日2007-10-27
公開日2008-06-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献A leishmania ortholog of macrophage migration inhibitory factor modulates host macrophage responses.
J.Immunol., 180, 2008
1QKG
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BU of 1qkg by Molmil
DNA DECAMER DUPLEX CONTAINING T-T DEWAR PHOTOPRODUCT
分子名称: DNA (5'-D(*CP*GP*CP*AP*(HYD)TP*+TP*AP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*TP*GP*CP*G)-3')
著者Lee, J.-H, Bae, S.-H, Choi, Y.-J, Choi, B.-S.
登録日1999-07-20
公開日2000-05-11
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献The Dewar Photoproduct of Thymidylyl(3'-->5')-Thymidine (Dewar Product) Exhibits Mutagenic Behavior in Accordance with the "A Rule".
Proc.Natl.Acad.Sci.USA, 97, 2000
2RVC
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BU of 2rvc by Molmil
Solution structure of Zalpha domain of goldfish ZBP-containing protein kinase
分子名称: Interferon-inducible and double-stranded-dependent eIF-2kinase
著者Lee, A, Park, C, Park, J, Kwon, M, Choi, Y, Kim, K, Choi, B, Lee, J.
登録日2015-07-08
公開日2016-02-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the Z-DNA binding domain of PKR-like protein kinase from Carassius auratus and quantitative analyses of the intermediate complex during B-Z transition.
Nucleic Acids Res., 44, 2016
4YVM
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BU of 4yvm by Molmil
X-ray structure of Helicobacter pylori CagL-K74
分子名称: Cag pathogenicity island protein
著者Choi, J.M, Choi, Y.H, Cha, J.H, Lee, S.H.
登録日2015-03-20
公開日2015-05-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.791 Å)
主引用文献Crystal structure of CagL from Helicobacter pylori K74 strain.
Biochem.Biophys.Res.Commun., 460, 2015
8DYO
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BU of 8dyo by Molmil
Cryo-EM structure of Importin-4 bound to RanGTP
分子名称: GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Importin-4, ...
著者Bernardes, N.E, Fung, H.Y.J, Li, Y, Chen, Z, Chook, Y.M.
登録日2022-08-04
公開日2022-09-21
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (7.1 Å)
主引用文献Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex.
Proc.Natl.Acad.Sci.USA, 119, 2022
2QMR
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BU of 2qmr by Molmil
Karyopherin beta2/transportin
分子名称: Transportin-1
著者Cansizoglu, A.E, Chook, Y.M.
登録日2007-07-16
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Conformational heterogeneity of karyopherin beta2 is segmental
Structure, 15, 2007
8GY0
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BU of 8gy0 by Molmil
Agrocybe pediades linalool sunthase (Ap.LS)
分子名称: Terpene synthase
著者Rehka, T, Sharma, D, Lin, F, Lim, C, Choong, Y.K, Chacko, J, Zhang, C.
登録日2022-09-21
公開日2023-04-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.988 Å)
主引用文献Structural Understanding of Fungal Terpene Synthases for the Formation of Linear or Cyclic Terpene Products.
Acs Catalysis, 13, 2023
7L5E
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BU of 7l5e by Molmil
Crystal Structure of KPT-330 bound to CRM1 (537-DLTVK-541 to GLCEQ)
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Baumhardt, J.M, Chook, Y.M.
登録日2020-12-21
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.944 Å)
主引用文献Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.
J Hematol Oncol, 14, 2021
8HAE
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BU of 8hae by Molmil
Cryo-EM structure of HACE1 dimer
分子名称: E3 ubiquitin-protein ligase HACE1
著者Singh, S, Machida, S, Tulsian, N.K, Choong, Y.K, Ng, J, Shanker, S, Yaochen, L.D, Shi, J, Sivaraman, J, Machida, S.
登録日2022-10-26
公開日2023-06-28
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (4.55 Å)
主引用文献Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization.
Adv Sci, 10, 2023
8H8X
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BU of 8h8x by Molmil
Cryo-EM structure of HACE1 monomer
分子名称: E3 ubiquitin-protein ligase HACE1
著者Singh, S, Machida, S, Tulsian, N.K, Choong, Y.K, Ng, J, Shanker, S, Yaochen, L.D, Shi, J, Sivaraman, J.
登録日2022-10-24
公開日2023-06-28
最終更新日2024-01-10
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization.
Adv Sci, 10, 2023
4OO6
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BU of 4oo6 by Molmil
Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1)
分子名称: RNA-binding protein 39, Transportin-1
著者Sampathkumar, P, Brower, A, Soniat, M, Bonanno, J, Hillerich, B, Seidel, R.D, Rout, M.P, Chook, Y.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals)
登録日2014-01-30
公開日2014-02-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1)
to be published
2WZQ
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BU of 2wzq by Molmil
Insertion Mutant E173GP174 of the NS3 protease-helicase from dengue virus
分子名称: CHLORIDE ION, GLYCEROL, NS3 PROTEASE-HELICASE
著者Luo, D, Wei, N, Doan, D, Paradkar, P, Chong, Y, Davidson, A, Kotaka, M, Lescar, J, Vasudevan, S.
登録日2009-12-02
公開日2010-04-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Flexibility between the Protease and Helicase Domains of the Dengue Virus Ns3 Protein Conferred by the Linker Region and its Functional Implications.
J.Biol.Chem., 285, 2010
6N34
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BU of 6n34 by Molmil
Crystal structure of the BTB domain of Human NS1-BP
分子名称: Influenza virus NS1A-binding protein
著者Zhang, K, Shang, G, Padavannil, A, Fontoura, B, Chook, Y.M.
登録日2018-11-14
公開日2018-12-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6N3H
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BU of 6n3h by Molmil
Crystal structure of Kelch domain of the human NS1 binding protein
分子名称: Influenza virus NS1A-binding protein
著者Zhang, K, Shang, G, Padavannil, A, Fontoura, B.M.A, Chook, Y.M.
登録日2018-11-15
公開日2018-12-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6N1Z
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BU of 6n1z by Molmil
Importin-9 bound to H2A-H2B
分子名称: Histone H2A, Histone H2B 1.1, Importin-9
著者Tomchick, D.R, Chook, Y.M, Padavannil, A.
登録日2018-11-12
公開日2019-03-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone.
Elife, 8, 2019
5B16
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BU of 5b16 by Molmil
X-ray structure of DROSHA in complex with the C-terminal tail of DGCR8.
分子名称: Microprocessor complex subunit DGCR8, Ribonuclease 3,DROSHA,Ribonuclease 3,DROSHA,Ribonuclease 3, ZINC ION
著者Kwon, S.C, Nguyen, T.A, Choi, Y.G, Jo, M.H, Hohng, S, Kim, V.N, Woo, J.S.
登録日2015-11-23
公開日2016-02-03
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Human DROSHA
Cell, 164, 2016
4GPT
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BU of 4gpt by Molmil
Crystal structure of KPT251 in complex with CRM1-Ran-RanBP1
分子名称: 1,2-ETHANEDIOL, 2-(2-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}ethyl)-1,3,4-oxadiazole, CHLORIDE ION, ...
著者Sun, Q, Chook, Y.M.
登録日2012-08-21
公開日2012-09-05
最終更新日2013-01-23
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells.
Leukemia, 27, 2013
4M0W
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BU of 4m0w by Molmil
Crystal Structure of SARS-CoV papain-like protease C112S mutant in complex with ubiquitin
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Replicase polyprotein 1a, ...
著者Chou, C.-Y, Chen, H.-Y, Lai, H.-Y, Cheng, S.-C, Chou, Y.-W.
登録日2013-08-02
公開日2014-02-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis for catalysis and ubiquitin recognition by the severe acute respiratory syndrome coronavirus papain-like protease
Acta Crystallogr.,Sect.D, 70, 2014
6XJR
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BU of 6xjr by Molmil
Crystal Structure of KPT-185 bound to CRM1 (E582K, 537-DLTVK-541 to GLCEQ)
分子名称: Exportin-1, GTP-binding nuclear protein Ran, MAGNESIUM ION, ...
著者Baumhardt, J.M, Chook, Y.M.
登録日2020-06-24
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.941 Å)
主引用文献Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.
J Hematol Oncol, 14, 2021
4JLQ
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BU of 4jlq by Molmil
Crystal structure of human Karyopherin-beta2 bound to the PY-NLS of Saccharomyces cerevisiae NAB2
分子名称: Nuclear polyadenylated RNA-binding protein NAB2, Transportin-1
著者Sampathkumar, P, Gizzi, A, Rout, M.P, Chook, Y.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals)
登録日2013-03-12
公開日2013-04-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structure of human Karyopherin beta 2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2.
J.Struct.Funct.Genom., 14, 2013
6XJP
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BU of 6xjp by Molmil
Crystal Structure of KPT-185 bound to CRM1 (537-DLTVK-541 to GLCEQ)
分子名称: Exportin-1, GTP-binding nuclear protein Ran, MAGNESIUM ION, ...
著者Baumhardt, J.M, Chook, Y.M.
登録日2020-06-24
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.
J Hematol Oncol, 14, 2021

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件を2024-10-30に公開中

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