7YQ6
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![BU of 7yq6 by Molmil](/molmil-images/mine/7yq6) | human insulin receptor bound with A62 DNA aptamer | Descriptor: | IR-A62 aptamer, Isoform Short of Insulin receptor | Authors: | Kim, J, Yunn, N, Ryu, S, Cho, Y. | Deposit date: | 2022-08-05 | Release date: | 2022-11-09 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures. Nat Commun, 13, 2022
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7YQ5
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![BU of 7yq5 by Molmil](/molmil-images/mine/7yq5) | human insulin receptor bound with A62 DNA aptamer and insulin | Descriptor: | IR-A62 aptamer, Insulin A chain, Insulin, ... | Authors: | Kim, J, Yunn, N, Ryu, S, Cho, Y. | Deposit date: | 2022-08-05 | Release date: | 2022-11-09 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.27 Å) | Cite: | Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures. Nat Commun, 13, 2022
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6LHW
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![BU of 6lhw by Molmil](/molmil-images/mine/6lhw) | Structure of N-terminal and C-terminal domains of FANCA | Descriptor: | Fanconi anemia complementation group A | Authors: | Jeong, E, Lee, S, Shin, J, Kim, Y, Kim, J, Scharer, O, Kim, Y, Kim, H, Cho, Y. | Deposit date: | 2019-12-10 | Release date: | 2020-03-25 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.84 Å) | Cite: | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex. Nucleic Acids Res., 48, 2020
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1N4M
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![BU of 1n4m by Molmil](/molmil-images/mine/1n4m) | Structure of Rb tumor suppressor bound to the transactivation domain of E2F-2 | Descriptor: | Retinoblastoma Pocket, Transcription factor E2F2 | Authors: | Lee, C, Chang, J.H, Lee, H.S, Cho, Y. | Deposit date: | 2002-10-31 | Release date: | 2003-01-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor GENES DEV., 16, 2002
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6LHV
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![BU of 6lhv by Molmil](/molmil-images/mine/6lhv) | Structure of FANCA and FANCG Complex | Descriptor: | Fanconi anemia complementation group A, Fanconi anemia complementation group G | Authors: | Jeong, E, Lee, S, Shin, J, Kim, Y, Scharer, O, Kim, Y, Kim, H, Cho, Y. | Deposit date: | 2019-12-10 | Release date: | 2020-03-25 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.59 Å) | Cite: | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex. Nucleic Acids Res., 48, 2020
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4TUM
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![BU of 4tum by Molmil](/molmil-images/mine/4tum) | Crystal structure of Ankyrin Repeat Domain of AKR2 | Descriptor: | Ankyrin repeat domain-containing protein 2 | Authors: | Gwon, G.H, Cho, Y. | Deposit date: | 2014-06-24 | Release date: | 2014-09-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | An Ankyrin Repeat Domain of AKR2 Drives Chloroplast Targeting through Coincident Binding of Two Chloroplast Lipids. Dev.Cell, 30, 2014
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8ATC
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![BU of 8atc by Molmil](/molmil-images/mine/8atc) | COMPLEX OF N-PHOSPHONACETYL-L-ASPARTATE WITH ASPARTATE CARBAMOYLTRANSFERASE. X-RAY REFINEMENT, ANALYSIS OF CONFORMATIONAL CHANGES AND CATALYTIC AND ALLOSTERIC MECHANISMS | Descriptor: | ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ... | Authors: | Ke, H, Lipscomb, W.N, Cho, Y, Honzatko, R.B. | Deposit date: | 1989-08-25 | Release date: | 1990-10-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Complex of N-phosphonacetyl-L-aspartate with aspartate carbamoyltransferase. X-ray refinement, analysis of conformational changes and catalytic and allosteric mechanisms. J.Mol.Biol., 204, 1988
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4R3Z
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![BU of 4r3z by Molmil](/molmil-images/mine/4r3z) | Crystal structure of human ArgRS-GlnRS-AIMP1 complex | Descriptor: | Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Arginine--tRNA ligase, cytoplasmic, ... | Authors: | Fu, Y, Kim, Y, Cho, Y. | Deposit date: | 2014-08-18 | Release date: | 2014-10-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (4.033 Å) | Cite: | Structure of the ArgRS-GlnRS-AIMP1 complex and its implications for mammalian translation Proc.Natl.Acad.Sci.USA, 111, 2014
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4TUG
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![BU of 4tug by Molmil](/molmil-images/mine/4tug) | Crystal structure of MjMre11-DNA2 complex | Descriptor: | DNA (5'-D(P*CP*TP*GP*TP*CP*CP*TP*AP*CP*GP*TP*GP*CP*CP*A)-3'), DNA (5'-D(P*GP*CP*AP*CP*GP*TP*AP*GP*GP*AP*CP*AP*GP*C)-3'), DNA double-strand break repair protein Mre11, ... | Authors: | Sung, S, Cho, Y. | Deposit date: | 2014-06-24 | Release date: | 2014-10-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.55 Å) | Cite: | DNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA. Embo J., 33, 2014
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4TUI
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![BU of 4tui by Molmil](/molmil-images/mine/4tui) | Crystal structure of MjMre11-DNA1 complex | Descriptor: | DNA (5'-D(P*TP*CP*CP*TP*AP*CP*GP*TP*GP*CP*CP*AP*G)-3'), DNA (5'-D(P*TP*GP*GP*CP*AP*CP*GP*TP*AP*GP*GP*AP*C)-3'), DNA double-strand break repair protein Mre11 | Authors: | Sung, S, Cho, Y. | Deposit date: | 2014-06-24 | Release date: | 2014-10-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.59 Å) | Cite: | DNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA. Embo J., 33, 2014
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5Y86
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![BU of 5y86 by Molmil](/molmil-images/mine/5y86) | Crystal structure of kinase | Descriptor: | 1,2-ETHANEDIOL, 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE, Dual specificity tyrosine-phosphorylation-regulated kinase 3, ... | Authors: | Kim, K.L, Cha, J.S, Cho, Y.S, Kim, H.Y, Chang, N.P, Cho, H.S. | Deposit date: | 2017-08-18 | Release date: | 2018-05-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of Human Dual-Specificity Tyrosine-Regulated Kinase 3 Reveals New Structural Features and Insights into its Auto-phosphorylation J. Mol. Biol., 430, 2018
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8GUY
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![BU of 8guy by Molmil](/molmil-images/mine/8guy) | human insulin receptor bound with two insulin molecules | Descriptor: | Insulin A chain, Insulin, isoform 2, ... | Authors: | Kim, J, Yunn, N, Ryu, S, Cho, Y. | Deposit date: | 2022-09-14 | Release date: | 2022-11-09 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures. Nat Commun, 13, 2022
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7CA3
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![BU of 7ca3 by Molmil](/molmil-images/mine/7ca3) | Cryo-EM structure of human GABA(B) receptor bound to the positive allosteric modulator rac-BHFF | Descriptor: | (3S)-5,7-ditert-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one, CHOLESTEROL, Gamma-aminobutyric acid type B receptor subunit 1, ... | Authors: | Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y. | Deposit date: | 2020-06-08 | Release date: | 2020-11-11 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural Basis for Activation of the Heterodimeric GABA B Receptor. J.Mol.Biol., 432, 2020
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7CA5
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![BU of 7ca5 by Molmil](/molmil-images/mine/7ca5) | Cryo-EM structure of human GABA(B) receptor in apo state | Descriptor: | Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2 | Authors: | Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y. | Deposit date: | 2020-06-08 | Release date: | 2020-11-11 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Structural Basis for Activation of the Heterodimeric GABA B Receptor. J.Mol.Biol., 432, 2020
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7CUM
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![BU of 7cum by Molmil](/molmil-images/mine/7cum) | Cryo-EM structure of human GABA(B) receptor bound to the antagonist CGP54626 | Descriptor: | (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, CHOLESTEROL, Gamma-aminobutyric acid type B receptor subunit 1, ... | Authors: | Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y. | Deposit date: | 2020-08-23 | Release date: | 2020-11-11 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Structural Basis for Activation of the Heterodimeric GABA B Receptor. J.Mol.Biol., 432, 2020
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1X3Z
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![BU of 1x3z by Molmil](/molmil-images/mine/1x3z) | Structure of a peptide:N-glycanase-Rad23 complex | Descriptor: | UV excision repair protein RAD23, ZINC ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... | Authors: | Lee, J.-H, Choi, J.M, Lee, C, Yi, K.J, Cho, Y. | Deposit date: | 2005-05-11 | Release date: | 2005-06-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of a peptide:N-glycanase-Rad23 complex: insight into the deglycosylation for denatured glycoproteins. Proc.Natl.Acad.Sci.Usa, 102, 2005
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1X3W
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![BU of 1x3w by Molmil](/molmil-images/mine/1x3w) | Structure of a peptide:N-glycanase-Rad23 complex | Descriptor: | UV excision repair protein RAD23, ZINC ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... | Authors: | Lee, J.-H, Choi, J.M, Lee, C, Yi, K.J, Cho, Y. | Deposit date: | 2005-05-11 | Release date: | 2005-06-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of a peptide:N-glycanase-Rad23 complex: insight into the deglycosylation for denatured glycoproteins. Proc.Natl.Acad.Sci.Usa, 102, 2005
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1GH6
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![BU of 1gh6 by Molmil](/molmil-images/mine/1gh6) | RETINOBLASTOMA POCKET COMPLEXED WITH SV40 LARGE T ANTIGEN | Descriptor: | Large T antigen, Retinoblastoma-associated protein | Authors: | Kim, H.Y, Cho, Y. | Deposit date: | 2000-11-15 | Release date: | 2001-11-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen. EMBO J., 20, 2001
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1H3Q
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![BU of 1h3q by Molmil](/molmil-images/mine/1h3q) | |
5E9G
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![BU of 5e9g by Molmil](/molmil-images/mine/5e9g) | Structural insights of isocitrate lyases from Magnaporthe oryzae | Descriptor: | GLYCEROL, GLYOXYLIC ACID, Isocitrate lyase, ... | Authors: | Park, Y, Cho, Y, Lee, Y.-H, Lee, Y.-W, Rhee, S. | Deposit date: | 2015-10-15 | Release date: | 2016-04-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure and functional analysis of isocitrate lyases from Magnaporthe oryzae and Fusarium graminearum J.Struct.Biol., 194, 2016
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5E9H
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![BU of 5e9h by Molmil](/molmil-images/mine/5e9h) | Structural insights of isocitrate lyases from Fusarium graminearum | Descriptor: | Isocitrate lyase, MALONATE ION, MANGANESE (II) ION | Authors: | Park, Y, Cho, Y, Lee, Y.-H, Lee, Y.-W, Rhee, S. | Deposit date: | 2015-10-15 | Release date: | 2016-04-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure and functional analysis of isocitrate lyases from Magnaporthe oryzae and Fusarium graminearum J.Struct.Biol., 194, 2016
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1WOU
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![BU of 1wou by Molmil](/molmil-images/mine/1wou) | Crystal Structure of human Trp14 | Descriptor: | thioredoxin -related protein, 14 kDa | Authors: | Woo, J.R, Kim, S.J, Jeong, W, Cho, Y.H, Lee, S.C, Chung, Y.J, Rhee, S.G, Ryu, S.E. | Deposit date: | 2004-08-25 | Release date: | 2004-09-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of cellular redox regulation by human TRP14 J.Biol.Chem., 279, 2004
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4YGQ
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![BU of 4ygq by Molmil](/molmil-images/mine/4ygq) | Crystal structure of HAD phosphatase from Thermococcus onnurineus | Descriptor: | Hydrolase, TERTIARY-BUTYL ALCOHOL | Authors: | Ngo, T.D, Le, B.V, Subramani, V.K, Nguyen, C.M.T, Lee, H.S, Cho, Y, Kim, K.K, Hwang, H.Y. | Deposit date: | 2015-02-26 | Release date: | 2015-04-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the substrate selectivity of a HAD phosphatase from Thermococcus onnurineus NA1 Biochem.Biophys.Res.Commun., 461, 2015
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4YGS
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![BU of 4ygs by Molmil](/molmil-images/mine/4ygs) | Crystal structure of HAD phosphatase from Thermococcus onnurineus | Descriptor: | CITRIC ACID, Hydrolase, MAGNESIUM ION | Authors: | Ngo, T.D, Le, B.V, Subramani, V.K, Nguyen, C.M.T, Lee, H.S, Cho, Y, Kim, K.K, Hwang, H.Y. | Deposit date: | 2015-02-26 | Release date: | 2015-04-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for the substrate selectivity of a HAD phosphatase from Thermococcus onnurineus NA1 Biochem.Biophys.Res.Commun., 461, 2015
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4YGR
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![BU of 4ygr by Molmil](/molmil-images/mine/4ygr) | Crystal structure of HAD phosphatase from Thermococcus onnurineus | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Hydrolase, MAGNESIUM ION | Authors: | Ngo, T.D, Le, B.V, Subramani, V.K, Nguyen, C.M.T, Lee, H.S, Cho, Y, Kim, K.K, Hwang, H.Y. | Deposit date: | 2015-02-26 | Release date: | 2015-04-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.703 Å) | Cite: | Structural basis for the substrate selectivity of a HAD phosphatase from Thermococcus onnurineus NA1 Biochem.Biophys.Res.Commun., 461, 2015
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