4ZGZ
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![BU of 4zgz by Molmil](/molmil-images/mine/4zgz) | |
5ZQF
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![BU of 5zqf by Molmil](/molmil-images/mine/5zqf) | Crystal structure of human topoisomerase II beta in complex with 5-iodouridine-containing-DNA in space group P3221 | Descriptor: | DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA topoisomerase 2-beta, DNA/RNA (5'-D(P*AP*GP*C)-R(P*(IU))-D(P*CP*GP*GP*C)-R(P*(IU))-3'), ... | Authors: | Chen, S.F, Wang, Y.R, Chan, N.L. | Deposit date: | 2018-04-18 | Release date: | 2018-08-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.873 Å) | Cite: | Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate. Nat Commun, 9, 2018
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5ZEN
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![BU of 5zen by Molmil](/molmil-images/mine/5zen) | Crystal structure of human topoisomerase II beta in complex with DNA: a new quaternary conformation showing opening of the protein-linked DNA-gate | Descriptor: | DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ... | Authors: | Chen, S.F, Wang, Y.R, Chan, N.L. | Deposit date: | 2018-02-27 | Release date: | 2018-08-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate. Nat Commun, 9, 2018
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5ZRF
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![BU of 5zrf by Molmil](/molmil-images/mine/5zrf) | Crystal structure of human topoisomerase II beta in complex with 5-iodouridine-containing-DNA and etoposide in space group p21 | Descriptor: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA topoisomerase 2-beta, ... | Authors: | Chen, S.F, Wang, Y.R, Wu, C.C, Chan, N.L. | Deposit date: | 2018-04-24 | Release date: | 2018-08-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate. Nat Commun, 9, 2018
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1XNL
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![BU of 1xnl by Molmil](/molmil-images/mine/1xnl) | ASLV fusion peptide | Descriptor: | membrane protein gp37 | Authors: | Cheng, S.F, Wu, C.W, Kantchev, E.A, Chang, D.K. | Deposit date: | 2004-10-05 | Release date: | 2005-01-11 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Structure and membrane interaction of the internal fusion peptide of avian sarcoma leukosis virus Eur.J.Biochem., 271, 2004
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5GWI
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![BU of 5gwi by Molmil](/molmil-images/mine/5gwi) | Structure of a Human topoisomerase IIbeta fragment in complex with DNA and E7873R | Descriptor: | DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ... | Authors: | Wang, Y.R, Chen, S.F, Wu, C.C, Chan, N.L. | Deposit date: | 2016-09-12 | Release date: | 2017-08-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.737 Å) | Cite: | Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry Nucleic Acids Res., 45, 2017
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5GWJ
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![BU of 5gwj by Molmil](/molmil-images/mine/5gwj) | Structure of a Human topoisomerase IIbeta fragment in complex with DNA and E7873S | Descriptor: | DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ... | Authors: | Wang, Y.R, Chen, S.F, Wu, C.C, Chan, N.L. | Deposit date: | 2016-09-12 | Release date: | 2017-08-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.566 Å) | Cite: | Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry Nucleic Acids Res., 45, 2017
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7KPW
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![BU of 7kpw by Molmil](/molmil-images/mine/7kpw) | Structure of the H-lobe of yeast CKM | Descriptor: | Mediator of RNA polymerase II transcription subunit 12 | Authors: | Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. | Deposit date: | 2020-11-12 | Release date: | 2021-01-27 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7, 2021
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7KPX
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![BU of 7kpx by Molmil](/molmil-images/mine/7kpx) | Structure of the yeast CKM | Descriptor: | Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ... | Authors: | Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. | Deposit date: | 2020-11-12 | Release date: | 2021-01-27 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7, 2021
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7KPV
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![BU of 7kpv by Molmil](/molmil-images/mine/7kpv) | Structure of kinase and Central lobes of yeast CKM | Descriptor: | Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ... | Authors: | Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. | Deposit date: | 2020-11-12 | Release date: | 2021-01-27 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7, 2021
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