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PDB: 74 件

5E5A
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BU of 5e5a by Molmil
Crystal structure of the chromatin-tethering domain of Human cytomegalovirus IE1 protein bound to the nucleosome core particle
分子名称: C-terminal domain of Regulatory protein IE1, DNA (146-MER), Histone H2A, ...
著者Fang, Q, Chen, P, Wang, M, Fang, J, Yang, N, Li, G, Xu, R.M.
登録日2015-10-08
公開日2016-02-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.809 Å)
主引用文献Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome
Elife, 5, 2016
3SR4
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BU of 3sr4 by Molmil
Crystal Structure of Human DOT1L in Complex with a Selective Inhibitor
分子名称: (2S)-2-azanyl-4-[[(2S,3S,4R,5R)-5-[6-(methylamino)purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid, ACETATE ION, GLYCEROL, ...
著者Diao, J, Chen, P, Yao, Y, Prasad, B.V.V, Song, Y.
登録日2011-07-06
公開日2011-10-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic Studies.
J.Am.Chem.Soc., 133, 2011
2JRY
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BU of 2jry by Molmil
Structure and Sodium Channel Activity of an Excitatory I1-Superfamily Conotoxin
分子名称: I-superfamily conotoxin r11a
著者Buczek, O, Wei, D, Babon, J, Yang, X, Fiedler, B, Chen, P, Yoshikami, D, Olivera, B, Bulaj, G, Norton, R.
登録日2007-06-29
公開日2007-10-23
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structure and sodium channel activity of an excitatory I1-superfamily conotoxin.
Biochemistry, 46, 2007
2LGK
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BU of 2lgk by Molmil
NMR Structure of UHRF1 PHD domains in a complex with histone H3 peptide
分子名称: E3 ubiquitin-protein ligase UHRF1, ZINC ION, histone H3 peptide
著者Wang, C, Shen, J, Yang, Z, Chen, P, Zhao, B, Hu, W, Lan, W, Tong, X, Wu, H, Li, G, Cao, C.
登録日2011-07-28
公開日2011-09-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
2LGG
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BU of 2lgg by Molmil
Structure of PHD domain of UHRF1 in complex with H3 peptide
分子名称: E3 ubiquitin-protein ligase UHRF1, ZINC ION, histone H3 peptide
著者Wang, C, Shen, J, Yang, Z, Chen, P, Zhao, B, Hu, W, Lan, W, Tong, X, Wu, H, Li, G, Cao, C.
登録日2011-07-26
公開日2011-09-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
2LGL
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BU of 2lgl by Molmil
NMR structure of the UHRF1 PHD domain
分子名称: E3 ubiquitin-protein ligase UHRF1, ZINC ION
著者Wang, C, Shen, J, Yang, Z, Chen, P, Zhao, B, Hu, W, Lan, W, Tong, X, Wu, H, Li, G, Cao, C.
登録日2011-07-28
公開日2011-09-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
7DH7
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BU of 7dh7 by Molmil
Crystal structure of apo XcZur
分子名称: PHOSPHATE ION, Transcriptional regulator fur family, ZINC ION
著者Liu, F.M, Su, Z.H, Chen, P, Tian, X.L, Wu, L.J, Tang, D.J, Li, P.F, Deng, H.T, Tang, J.L, Ming, Z.H.
登録日2020-11-13
公開日2021-06-09
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for zinc-induced activation of a zinc uptake transcriptional regulator.
Nucleic Acids Res., 49, 2021
7DH8
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BU of 7dh8 by Molmil
Crystal structure of holo XcZur
分子名称: Transcriptional regulator fur family, ZINC ION
著者Liu, F.M, Su, Z.H, Chen, P, Tian, X.L, Wu, L.J, Tang, D.J, Li, P.F, Deng, H.T, Tang, J.L, Ming, Z.H.
登録日2020-11-13
公開日2021-06-09
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis for zinc-induced activation of a zinc uptake transcriptional regulator.
Nucleic Acids Res., 49, 2021
6Z14
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BU of 6z14 by Molmil
Structure of Bifidobacterium bifidum GH20 beta-N-beta-N-acetylhexosaminidase E553Q variant in complex with 4MU-6SGlcNAc-derived oxazoline
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-N-acetylhexosaminidase, NITRATE ION, ...
著者He, Y, Jin, Y, Rizkallah, P, Chen, P.
登録日2020-05-12
公開日2021-05-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structure and activity of the GH20 beta-N-beta-N-acetylhexosaminidase from Bifidobacterium bifidum
To Be Published
4OU6
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BU of 4ou6 by Molmil
Crystal structure of DnaT84-153-dT10 ssDNA complex form 1
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Primosomal protein 1
著者Liu, Z, Chen, P, Niu, L, Teng, M, Li, X.
登録日2014-02-15
公開日2014-08-13
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structure of DnaT84-153-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode.
Nucleic Acids Res., 42, 2014
4OU7
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Crystal structure of DnaT84-153-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Primosomal protein 1
著者Liu, Z, Chen, P, Niu, L, Teng, M, Li, X.
登録日2014-02-15
公開日2014-08-13
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Crystal structure of DnaT84-153-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode.
Nucleic Acids Res., 42, 2014
5YHY
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BU of 5yhy by Molmil
Structure of Lactococcus lactis ZitR, C30S mutant
分子名称: ZINC ION, Zinc transport transcriptional regulator
著者Song, Y, Liu, H, Zhu, R, Yi, C, Chen, P.
登録日2017-10-01
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
5YI3
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BU of 5yi3 by Molmil
Structure of Lactococcus lactis ZitR, C30S mutant in complex with DNA
分子名称: DNA (5'-D(*TP*GP*TP*TP*AP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*A)-3'), ZINC ION, Zinc transport transcriptional regulator
著者Song, Y, Liu, H, Zhu, R, Yi, C, Chen, P.
登録日2017-10-01
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
5YHZ
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BU of 5yhz by Molmil
Structure of Lactococcus lactis ZitR, E41A mutant
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ZINC ION, ...
著者Song, Y, Liu, H, Zhu, R, Yi, C, Chen, P.
登録日2017-10-01
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
5YHX
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BU of 5yhx by Molmil
Structure of Lactococcus lactis ZitR, wild type
分子名称: ZINC ION, Zinc transport transcriptional regulator
著者Song, Y, Liu, H, Zhu, R, Yi, C, Chen, P.
登録日2017-10-01
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
5YI0
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BU of 5yi0 by Molmil
Structure of Lactococcus lactis ZitR, C30AH42A mutant
分子名称: ZINC ION, Zinc transport transcriptional regulator
著者Song, Y, Liu, H, Zhu, R, Yi, C, Chen, P.
登録日2017-10-01
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
5YI1
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BU of 5yi1 by Molmil
Structure of Lactococcus lactis ZitR, C30AH42A mutant in apo form
分子名称: Zinc transport transcriptional regulator
著者Song, Y, Liu, H, Zhu, R, Yi, C, Chen, P.
登録日2017-10-01
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
5YI2
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BU of 5yi2 by Molmil
Structure of Lactococcus lactis ZitR, wild type in complex with DNA
分子名称: DNA (5'-D(*TP*GP*TP*TP*AP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*A)-3'), ZINC ION, Zinc transport transcriptional regulator
著者Song, Y, Liu, H, Zhu, R, Yi, C, Chen, P.
登録日2017-10-01
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
7UIA
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BU of 7uia by Molmil
Crystal structure of BoNT/E receptor binding domain in complex with SV2 and VHH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Liu, Z, Jin, R, Chen, P.
登録日2022-03-28
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023
7UIB
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Crystal structure of BoNT/E receptor binding domain in complex with SV2, VHH, and sialic acid
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-beta-neuraminic acid, ...
著者Liu, Z, Jin, R, Chen, P.
登録日2022-03-29
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023
7DPN
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BU of 7dpn by Molmil
Crystal structure of BRD2(BD1)with ligand ZB-BD-224 bound
分子名称: 5-(1-naphthoyl)-11-methyl-8-((methylsulfonyl)methyl)-4,5-dihydro-2,3a1,5-triazadibenzo[cd,h]azulen-1(2H)-one, Bromodomain-containing protein 2
著者Li, Z, Lu, T, Chen, P, Luo, C, Zhou, B.
登録日2020-12-20
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.79998839 Å)
主引用文献Structure Base Design of A new chemotype of Four-Cycle Compounds as Bromodomain and Extra-Terminal (BET) Inhibitors with The Second Bromodomain Bias and Highly Anti-inflammatory Potency
To Be Published
7DPO
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Crystal Structure of BRD2(BD2)with Ligand ZB-BD-224 bound
分子名称: 5-(1-naphthoyl)-11-methyl-8-((methylsulfonyl)methyl)-4,5-dihydro-2,3a1,5-triazadibenzo[cd,h]azulen-1(2H)-one, Bromodomain-containing protein 2
著者Li, Z, Lu, T, Chen, P, Luo, C, Zhou, B.
登録日2020-12-21
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.29994035 Å)
主引用文献Structure Base Design of A new chemotype of Four-Cycle Compounds as Bromodomain and Extra-Terminal (BET) Inhibitors with The Second Bromodomain Bias and Highly Anti-inflammatory Potency
To Be Published
7COM
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BU of 7com by Molmil
Crystal structure of the SARS-CoV-2 main protease in complex with Boceprevir (space group P212121)
分子名称: 3C-like proteinase, boceprevir (bound form)
著者Zeng, R, Qiao, J.X, Wang, Y.F, Li, Y.S, Yao, R, Liu, J.M, Zhou, Y.L, Chen, P, Yang, S.Y, Lei, J.
登録日2020-08-04
公開日2020-08-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献SARS-CoV-2 M pro inhibitors with antiviral activity in a transgenic mouse model.
Science, 371, 2021
7XCD
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Crystal Structure of the Disease-Specific Protein of Rice Stripe Virus
分子名称: Disease specific protein
著者Wu, Y.K, Chen, L.F, Chen, P.
登録日2022-03-24
公開日2023-04-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Crystal Structure of the Disease-Specific Protein of Rice Stripe Virus
To Be Published
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