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PDB: 616 件
6BUY
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BU of 6buy by Molmil
Crystal structure of porcine aminopeptidase-N with Glycine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, L, Lin, Y.-L, Li, F.
登録日2017-12-11
公開日2018-01-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach.
Sci Rep, 7, 2017
6BV0
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BU of 6bv0 by Molmil
Crystal structure of porcine aminopeptidase-N with Arginine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, L, Lin, Y.-L, Li, F.
登録日2017-12-12
公開日2018-01-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach.
Sci Rep, 7, 2017
6BV1
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BU of 6bv1 by Molmil
Crystal structure of porcine aminopeptidase-N with Aspartic acid
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, L, Lin, Y.-L, Li, F.
登録日2017-12-12
公開日2018-01-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach.
Sci Rep, 7, 2017
2P8T
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BU of 2p8t by Molmil
Hypothetical protein PH0730 from Pyrococcus horikoshii OT3
分子名称: Hypothetical protein PH0730
著者Chen, L, Zhao, M, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Zhu, J, Swindell, J.T, Fu, Z.-Q, Chrzas, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-23
公開日2007-04-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Hypothetical protein PH0730 from Pyrococcus horikoshii OT3
To be Published
6BV3
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BU of 6bv3 by Molmil
Crystal structure of porcine aminopeptidase-N with Leucine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, L, Lin, Y.-L, Li, F.
登録日2017-12-12
公開日2018-01-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach.
Sci Rep, 7, 2017
8K5G
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BU of 8k5g by Molmil
Structure of the SARS-CoV-2 BA.1 RBD with UT28-RD
分子名称: Spike protein S1, UT28K-RD Fab Heavy chain, UT28K-RD Fab Light chain
著者Chen, L, Kita, S, Anraku, Y, Maenaka, K.
登録日2023-07-21
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献In silico-designed UT28K with two amino acid substitutions is capable of neutralization of resistant SARS-CoV2 Omicrons BA.1 valiant.
To Be Published
3RJ2
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BU of 3rj2 by Molmil
Structural and functional characterization of a novel histone H3 binding protein ORF158L from the Singapore grouper iridovirus (SGIV)
分子名称: Putative uncharacterized protein
著者Chen, L, Liu, Y, Sivaraman, J, Hew, C.L.
登録日2011-04-15
公開日2012-02-29
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Novel histone H3 binding protein ORF158L from the Singapore grouper iridovirus
J.Virol., 85, 2011
3MQ0
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BU of 3mq0 by Molmil
Crystal Structure of Agobacterium tumefaciens repressor BlcR
分子名称: Transcriptional repressor of the blcABC operon
著者Chen, L.
登録日2010-04-27
公開日2011-03-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.793 Å)
主引用文献The Agrobacterium tumefaciens Transcription Factor BlcR Is Regulated via Oligomerization.
J.Biol.Chem., 286, 2011
4HOM
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BU of 4hom by Molmil
Crystal structure of porcine aminopeptidase-N complexed with substance P
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, L, Lin, Y.L, Peng, G, Li, F.
登録日2012-10-22
公開日2012-10-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for multifunctional roles of mammalian aminopeptidase N.
Proc.Natl.Acad.Sci.USA, 109, 2012
3JUA
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BU of 3jua by Molmil
Structural basis of YAP recognition by TEAD4 in the Hippo pathway
分子名称: 65 kDa Yes-associated protein, Transcriptional enhancer factor TEF-3
著者Chen, L, Song, H.
登録日2009-09-15
公開日2010-02-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of YAP recognition by TEAD4 in the hippo pathway.
Genes Dev., 24, 2010
3LLP
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BU of 3llp by Molmil
1.8 Angstrom human fascin 1 crystal structure
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BROMIDE ION, Fascin, ...
著者Chen, L, Yang, S, Jakoncic, J, Zhang, J.J, Huang, X.-Y.
登録日2010-01-29
公開日2010-04-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Migrastatin analogues target fascin to block tumour metastasis.
Nature, 464, 2010
3RPT
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BU of 3rpt by Molmil
Crystal structure of the anti-HIV b12 scaffold protein
分子名称: Endoglucanase E-2, SULFATE ION
著者Chen, L, Kwong, P.D.
登録日2011-04-27
公開日2011-12-21
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.303 Å)
主引用文献Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold.
Science, 334, 2011
4NAQ
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BU of 4naq by Molmil
Crystal structure of porcine aminopeptidase-N complexed with poly-alanine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ...
著者Chen, L, Lin, Y.L, Peng, G, Li, F.
登録日2013-10-22
公開日2013-12-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for multifunctional roles of mammalian aminopeptidase N.
Proc.Natl.Acad.Sci.USA, 109, 2012
8HBW
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BU of 8hbw by Molmil
Structure of human UCP1 in the ATP-bound state
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CARDIOLIPIN, ...
著者Chen, L, Kang, Y.
登録日2022-10-31
公開日2023-06-21
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (2.57 Å)
主引用文献Structural basis for the binding of DNP and purine nucleotides onto UCP1.
Nature, 620, 2023
8HBV
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BU of 8hbv by Molmil
Structure of human UCP1 in the nucleotide-free state
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CARDIOLIPIN, Mitochondrial brown fat uncoupling protein 1, ...
著者Chen, L, Kang, Y.
登録日2022-10-31
公開日2023-06-21
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Structural basis for the binding of DNP and purine nucleotides onto UCP1.
Nature, 620, 2023
8HBH
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BU of 8hbh by Molmil
Structure of human soluble guanylate cyclase in the NO-activated state at 3.1 angstrom
分子名称: Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, MAGNESIUM ION, ...
著者Chen, L, Liu, R.
登録日2022-10-28
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献NO binds to the distal site of haem in the fully activated soluble guanylate cyclase.
Nitric Oxide, 134-135, 2023
8HBE
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BU of 8hbe by Molmil
Structure of human soluble guanylate cyclase in the inactive state at 3.1 angstrom
分子名称: Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, PROTOPORPHYRIN IX CONTAINING FE
著者Chen, L, Liu, R.
登録日2022-10-28
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献NO binds to the distal site of haem in the fully activated soluble guanylate cyclase.
Nitric Oxide, 134-135, 2023
8HBF
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BU of 8hbf by Molmil
Structure of human soluble guanylate cyclase in the NO+Rio state at 3.1 angstrom
分子名称: Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, MAGNESIUM ION, ...
著者Chen, L, Liu, R.
登録日2022-10-28
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献NO binds to the distal site of haem in the fully activated soluble guanylate cyclase.
Nitric Oxide, 134-135, 2023
4NZ8
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BU of 4nz8 by Molmil
Crystal structure of porcine aminopeptidase-N complexed with cleaved poly-alanine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ...
著者Chen, L, Lin, Y.L, Peng, G, Li, F.
登録日2013-12-11
公開日2013-12-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for multifunctional roles of mammalian aminopeptidase N.
Proc.Natl.Acad.Sci.USA, 109, 2012
2ICU
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BU of 2icu by Molmil
Crystal Structure of Hypothetical Protein YedK From Escherichia coli
分子名称: Hypothetical protein yedK
著者Chen, L, Liu, Z.J, Li, Y, Zhao, M, Rose, J, Ebihara, A, Yokoyama, S, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-09-13
公開日2006-11-07
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Hypothetical Protein YedK From Escherichia coli
To be Published
8J1N
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BU of 8j1n by Molmil
Structure of human UCP1 in the DNP-bound state
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2,4-DINITROPHENOL, CARDIOLIPIN, ...
著者Chen, L, Kang, Y.
登録日2023-04-13
公開日2023-06-21
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Structural basis for the binding of DNP and purine nucleotides onto UCP1.
Nature, 620, 2023
2JTK
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BU of 2jtk by Molmil
A functional domain of a Wnt signal protein
分子名称: Dickkopf-related protein 2
著者Chen, L, Shao, Y, Huang, J, Zheng, J.
登録日2007-08-02
公開日2008-07-08
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structural insight into the mechanisms of wnt signaling antagonism by dkk
J.Biol.Chem., 283, 2008
2KNO
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BU of 2kno by Molmil
NMR Solution Structure of SH2 Domain of the Human Tensin Like C1 Domain Containing Phosphatase (TENC1)
分子名称: Tensin-like C1 domain-containing phosphatase
著者Chen, L, Feng, R, Liu, C, Zhu, G.
登録日2009-08-27
公開日2010-09-01
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of SH2 Domain of the Human Tensin Like C1 Domain Containing Phosphatase (TENC1)
To be Published
5CH9
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BU of 5ch9 by Molmil
Gkap mutant B12
分子名称: COBALT (II) ION, Phosphotriesterase
著者Chen, L.-Q.
登録日2015-07-10
公開日2015-09-09
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Active site loop architecture enhance the promiscuous PTE activity in lactonase from Geobacillus kaustophilus HTA426
To Be Published
2LHK
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BU of 2lhk by Molmil
Structural analysis of a chaperone in type III secretion system
分子名称: L0052
著者Chen, L, Economou, A, Kalodimos, C.G.
登録日2011-08-11
公開日2011-12-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural instability tuning as a regulatory mechanism in protein-protein interactions.
Mol.Cell, 44, 2011

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件を2024-05-29に公開中

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