6OCV
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6IQC
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![BU of 6iqc by Molmil](/molmil-images/mine/6iqc) | Wild-type Programmed Cell Death 5 protein from Sulfolobus solfataricus | Descriptor: | DNA-binding protein SSO0352, SODIUM ION, TETRAETHYLENE GLYCOL | Authors: | Chen, C.Y, Lin, K.F, Hsu, C.Y, Tsai, M.J. | Deposit date: | 2018-11-06 | Release date: | 2019-02-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Crystal structure of the programmed cell death 5 protein from Sulfolobus solfataricus. Acta Crystallogr F Struct Biol Commun, 75, 2019
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6IQO
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![BU of 6iqo by Molmil](/molmil-images/mine/6iqo) | Se-Met L45M Programmed Cell Death 5 protein from Sulfolobus solfataricus | Descriptor: | DNA-binding protein SSO0352, NONAETHYLENE GLYCOL | Authors: | Chen, C.Y, Lin, K.F, Hsu, C.Y, Tsai, M.J. | Deposit date: | 2018-11-08 | Release date: | 2019-02-20 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Crystal structure of the programmed cell death 5 protein from Sulfolobus solfataricus. Acta Crystallogr F Struct Biol Commun, 75, 2019
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6JD1
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![BU of 6jd1 by Molmil](/molmil-images/mine/6jd1) | Cryo-EM Structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) in complex with Mg2+, NADH, and CPD at pH7.5 | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MAGNESIUM ION, Putative ketol-acid reductoisomerase 2, ... | Authors: | Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D. | Deposit date: | 2019-01-30 | Release date: | 2019-04-17 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase. J. Am. Chem. Soc., 141, 2019
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6JD2
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![BU of 6jd2 by Molmil](/molmil-images/mine/6jd2) | Crystal structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) in complex with Mg2+ at pH8.5 | Descriptor: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, Putative ketol-acid reductoisomerase 2 | Authors: | Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D. | Deposit date: | 2019-01-30 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase. J.Am.Chem.Soc., 141, 2019
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6JCW
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![BU of 6jcw by Molmil](/molmil-images/mine/6jcw) | Cryo-EM Structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) with Mg2+ at pH8.5 | Descriptor: | MAGNESIUM ION, ketol-acid reductoisomerase | Authors: | Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D. | Deposit date: | 2019-01-30 | Release date: | 2019-04-17 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase. J. Am. Chem. Soc., 141, 2019
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6JCV
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![BU of 6jcv by Molmil](/molmil-images/mine/6jcv) | Cryo-EM structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) with Mg2+ at pH7.5 | Descriptor: | MAGNESIUM ION, Putative ketol-acid reductoisomerase 2 | Authors: | Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D. | Deposit date: | 2019-01-30 | Release date: | 2019-04-17 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase. J. Am. Chem. Soc., 141, 2019
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6JCZ
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![BU of 6jcz by Molmil](/molmil-images/mine/6jcz) | Cryo-EM Structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) in complex with Mg2+, NADPH, and CPD at pH7.5 | Descriptor: | MAGNESIUM ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative ketol-acid reductoisomerase 2, ... | Authors: | Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D. | Deposit date: | 2019-01-30 | Release date: | 2019-04-17 | Last modified: | 2019-05-01 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase. J. Am. Chem. Soc., 141, 2019
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6KQK
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![BU of 6kqk by Molmil](/molmil-images/mine/6kqk) | 323 K cryoEM structure of Sso-KARI in complex with Mg2+, NADH and CPD | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Ketol-acid reductoisomerase, MAGNESIUM ION, ... | Authors: | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | Deposit date: | 2019-08-18 | Release date: | 2020-03-25 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.17 Å) | Cite: | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions. J.Am.Chem.Soc., 141, 2019
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3O7L
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3UCI
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![BU of 3uci by Molmil](/molmil-images/mine/3uci) | Crystal structure of Rhodostomin ARLDDL mutant | Descriptor: | disintegrin | Authors: | Shiu, J.H, Chen, C.Y, Chen, Y.C, Chang, Y.T, Chang, Y.S, Huang, C.H, Chuang, W.J. | Deposit date: | 2011-10-27 | Release date: | 2012-11-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Design of Integrin AlphaVbeta3-Specific Disintegrin for Cancer Therapy To be Published
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1Q7J
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1Q7I
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7YPL
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5ITM
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![BU of 5itm by Molmil](/molmil-images/mine/5itm) | The structure of truncated histone-like protein | Descriptor: | AbrB family transcriptional regulator | Authors: | Lin, B.L, Chen, C.Y, Huang, C.H, Ko, T.P, Chiang, C.H, Lin, K.F, Chang, Y.C, Lin, P.Y, Tsai, H.H.G, Wang, A.H.J. | Deposit date: | 2016-03-17 | Release date: | 2017-01-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The Arginine Pairs and C-Termini of the Sso7c4 from Sulfolobus solfataricus Participate in Binding and Bending DNA. PLoS ONE, 12, 2017
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5ITJ
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![BU of 5itj by Molmil](/molmil-images/mine/5itj) | The structure of histone-like protein | Descriptor: | AbrB family transcriptional regulator, SULFATE ION, TETRAETHYLENE GLYCOL | Authors: | Lin, B.L, Chen, C.Y, Huang, C.H, Ko, T.P, Chiang, C.H, Lin, K.F, Chang, Y.C, Lin, P.Y, Tsai, H.H.G, Wang, A.H.J. | Deposit date: | 2016-03-17 | Release date: | 2017-01-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | The Arginine Pairs and C-Termini of the Sso7c4 from Sulfolobus solfataricus Participate in Binding and Bending DNA. PLoS ONE, 12, 2017
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2PJF
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![BU of 2pjf by Molmil](/molmil-images/mine/2pjf) | Solution structure of rhodostomin | Descriptor: | Rhodostoxin-disintegrin rhodostomin | Authors: | Chuang, W.J, Chen, Y.C, Chen, C.Y, Chang, Y.T. | Deposit date: | 2007-04-16 | Release date: | 2007-05-08 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Effect of D to E mutation of the RGD motif in rhodostomin on its activity, structure, and dynamics: Importance of the interactions between the D residue and integrin Proteins, 2009
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2PJG
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![BU of 2pjg by Molmil](/molmil-images/mine/2pjg) | Solution structure of rhodostomin D51E mutant | Descriptor: | Rhodostoxin-disintegrin rhodostomin | Authors: | Chuang, W.J, Chen, Y.C, Chen, C.Y, Chou, L.J. | Deposit date: | 2007-04-16 | Release date: | 2007-05-08 | Last modified: | 2021-11-10 | Method: | SOLUTION NMR | Cite: | Effect of D to E mutation of the RGD motif in rhodostomin on its activity, structure, and dynamics: Importance of the interactions between the D residue and integrin Proteins, 2009
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4M4C
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![BU of 4m4c by Molmil](/molmil-images/mine/4m4c) | Crystal structure of Rhodostomin ARGDP mutant | Descriptor: | SULFATE ION, Zinc metalloproteinase/disintegrin | Authors: | Chang, Y.T, Jeng, W.Y, Shiu, J.H, Chen, C.Y, Chuang, W.J. | Deposit date: | 2013-08-07 | Release date: | 2014-08-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Effect of C-terminal proline residue adjacent to the RGD motif in rhodostomin on its activity and structure To be Published
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5YEQ
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![BU of 5yeq by Molmil](/molmil-images/mine/5yeq) | The structure of Sac-KARI protein | Descriptor: | 1,2-ETHANEDIOL, Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION, ... | Authors: | Ko, T.P, Chen, C.Y, Lin, K.F, Lin, B.L, Huang, C.H, Chiang, C.H, Horng, J.C, Tsai, M.D. | Deposit date: | 2017-09-19 | Release date: | 2018-07-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | NADH/NADPH bi-cofactor-utilizing and thermoactive ketol-acid reductoisomerase from Sulfolobus acidocaldarius Sci Rep, 8, 2018
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4JVA
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![BU of 4jva by Molmil](/molmil-images/mine/4jva) | Crystal Structure of RIIbeta(108-402) bound to HE33, a N6 di-propyl substituted cAMP analog | Descriptor: | (2R,4aR,6R,7R,7aS)-6-[6-(dipropylamino)-9H-purin-9-yl]tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide, cAMP-dependent protein kinase type II-beta regulatory subunit | Authors: | Brown, S.H.J, Cheng, C.Y, Saldanha, A.S, Wu, J, Cottam, H, Sankaran, B, Taylor, S.S. | Deposit date: | 2013-03-25 | Release date: | 2013-09-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs. Acs Chem.Biol., 8, 2013
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4JV4
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![BU of 4jv4 by Molmil](/molmil-images/mine/4jv4) | Crystal Structure of RIalpha(91-379) bound to HE33, a N6 di-propyl substituted cAMP analog | Descriptor: | (2R,4aR,6R,7R,7aS)-6-[6-(dipropylamino)-9H-purin-9-yl]tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide, cAMP-dependent protein kinase type I-alpha regulatory subunit | Authors: | Brown, S.H.J, Cheng, C.Y, Saldanha, A.S, Wu, J, Cottam, H, Sankaran, B, Taylor, S.S. | Deposit date: | 2013-03-25 | Release date: | 2013-09-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.952 Å) | Cite: | Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs. Acs Chem.Biol., 8, 2013
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2QCS
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![BU of 2qcs by Molmil](/molmil-images/mine/2qcs) | A complex structure between the Catalytic and Regulatory subunit of Protein Kinase A that represents the inhibited state | Descriptor: | ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Kim, C, Cheng, C.Y, Saldanha, A.S, Taylor, S.S. | Deposit date: | 2007-06-19 | Release date: | 2007-11-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation. Cell(Cambridge,Mass.), 130, 2007
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