6JD2
Crystal structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) in complex with Mg2+ at pH8.5
Summary for 6JD2
Entry DOI | 10.2210/pdb6jd2/pdb |
Descriptor | Putative ketol-acid reductoisomerase 2, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | bi-specific, thermostable, reductoisomerase, magnesium-dependent, dodecamer, knotted protein, isomerase |
Biological source | Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) |
Total number of polymer chains | 12 |
Total formula weight | 448279.18 |
Authors | Chen, C.Y.,Chang, Y.C.,Lin, K.F.,Huang, C.H.,Lin, B.L.,Ko, T.P.,Hsieh, D.L.,Tsai, M.D. (deposition date: 2019-01-30, release date: 2019-08-14, Last modification date: 2023-11-22) |
Primary citation | Chen, C.Y.,Chang, Y.C.,Lin, B.L.,Lin, K.F.,Huang, C.H.,Hsieh, D.L.,Ko, T.P.,Tsai, M.D. Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase. J.Am.Chem.Soc., 141:6136-6140, 2019 Cited by PubMed: 30921515DOI: 10.1021/jacs.9b01354 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.53 Å) |
Structure validation
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